Aminophenols
Medchemexpress LLC RGX-104 hydrochloride | 610318-03-1 | 99.9% | 632.54 | 10 MG
RGX-104 hydrochloride is a small-molecule LXR agonist that modulates innate immunity through the transcriptional activation of the ApoE gene. It is intended for research use only.
- Modulates innate immunity via transcriptional activation of the ApoE gene.
- Potential anti-cancer activity through suppression of various cancer types, including lung cancer, melanoma, glioblastoma, ovarian, renal cell, triple-negative breast, and colon cancer.
- Induces tumor regression in some cases.
- Available in various quantities.
Medchemexpress LLC L-NAME (hydrochloride) | 51298-62-5 | 99.9% | 269.69 | 5 G
L-NAME hydrochloride is an inhibitor of nitric oxide synthase (NOS) with an IC50 of 70 μM. It acts as a precursor to the NOS inhibitor L-NOARG, which has an IC50 value of 1.4 μM. It is used for research purposes only and is not sold to patients.
- Inhibits NOS with an IC50 of 70 μM.
- Precursor to the more potent NOS inhibitor L-NOARG (IC50 = 1.4 μM).
- Can be used to induce hypertension models in animals.
- Can be used to induce preeclampsia models in animals.
Medchemexpress LLC R 59-022 (hydrochloride) | 93076-98-3 | MFCD34676749 | 98.9% | 496.04 | C27H27ClFN3OS | 5 MG
R 59-022 (hydrochloride) is a research-grade small-molecule inhibitor used to probe diacylglycerol kinase (DGK) activity and downstream lipid signaling pathways in biochemical and cellular studies. The compound is supplied as a hydrochloride salt with reported molecular weight 496.04 and high analytical purity appropriate for laboratory research applications.
- Selective diacylglycerol kinase inhibitor activity.
- Potentiates protein kinase C activation in cellular assays.
- High purity suitable for biochemical and cell-based studies.
- Supplied as a hydrochloride salt to aid solubility in polar solvents.
- Provided in small research pack sizes for laboratory use.
Medchemexpress LLC Guvacine hydrochloride | 6027-91-4 | MFCD00055191 | 99.9% | 163.60 g/mol | C6H10ClNO2 | 25 MG
Guvacine hydrochloride is the hydrochloride salt of guvacine, a pyridine alkaloid that acts as a GABA uptake inhibitor. Supplied as a high-purity research reagent, it is used in biochemical and neuropharmacological studies to probe GABA transporter activity. The substance is intended for laboratory research use only and is not for human or veterinary use.
- High purity (99.93%) for reliable experimental results.
- Molecular weight 163.60 g/mol.
- Molecular formula C6H10ClNO2.
- CAS number 6027-91-4 for unambiguous identification.
- Available in multiple pack sizes and solution formats for flexible use.
- Suitable for in vitro biochemical and pharmacology research.
Medchemexpress LLC RS100329 hydrochloride | 1215654-26-4 | 99.6% | 462.89 g/mol | C20H26ClF3N4O3 | 25 MG
RS100329 hydrochloride is the hydrochloride salt of RS100329, a potent and selective α1A-adrenoceptor antagonist used in pharmacological research, including studies of urethral reflex contractions and benign prostatic hyperplasia. It is supplied as a solid research chemical with high reported purity and defined storage recommendations.
- Potent, selective α1A-adrenoceptor antagonist (pKi 9.6 for α1A).
- High purity (≈99.6% by HPLC), suitable for biochemical assays.
- Well-characterized small molecule: molecular weight 462.89 g/mol, formula C20H26ClF3N4O3.
- Provided as a solid hydrochloride salt for accurate dosing in experiments.
- Recommended storage: 4°C protected from light; in solvent, -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Bi-9627 (hydrochloride) | 1422252-46-7 | 98.01% | 392.80 | 1 ML
BI-9627 hydrochloride is a potent inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1), exhibiting high selectivity over NHE2 and no measurable activity against NHE3. This compound shows low agent-agent interaction potential, excellent pharmacokinetics, and potent activity in isolated heart models of ischemia-reperfusion injury. It is intended for research use only.
- Decreases autophagy in HTR-8/SVneo cells.
- Significantly reduces the pHi of human sperm and partially reverses the effect of DMA.
- Prolongs Ca2+ recovery time in KO hiPSC-CMs.
- Shows low DDI potential.
- Excellent pharmacokinetics in rat and dog.
- Potent activity in isolated heart models of ischemia-reperfusion injury.
Medchemexpress LLC His-pro (hydrochloride) | 2415727-78-3 | 99.8% | 288.73 | 10 MG
His-Pro hydrochloride, also known as Histidyl-proline hydrochloride, is a dipeptide composed of histidyl and proline. This compound is commonly used in laboratory research.
- Dipeptide
- Solid appearance
- White to off-white color
Medchemexpress LLC Metixene hydrochloride hydrate | 7081-40-5 | ≥95.0% | 5MG
Metixene hydrochloride hydrate | 7081-40-5 | ≥95.0% | 5MG
Medchemexpress LLC L-NAME hydrochloride (NG-Nitroarginine methyl ester hydrochloride) | 51298-62-5 | 99.9% | 269.69 | 500 MG
L-NAME hydrochloride is a nitric oxide synthase (NOS) inhibitor with an IC50 of 70 μM. It acts as a precursor to the more potent NOS inhibitor L-NOARG (IC50 of 1.4 μM), making it valuable in studies of L-arginine analogues that inhibit NOS activity. Its efficacy can increase with prolonged incubation at neutral or alkaline pH, correlating with its hydrolysis to L-NOARG. This compound is also used to induce hypertension and preeclampsia models in animal studies.
- Inhibits NOS with an IC50 of 70 μM.
- Precursor to NOS inhibitor L-NOARG.
- Used to induce hypertension and preeclampsia models in animal studies.
- Appearance: solid, white to off-white.
- Storage: -20°C, sealed, away from moisture.
- In solvent: -80°C for 6 months; -20°C for 1 month.
Medchemexpress LLC CX-6258 hydrochloride | 1353859-00-3 | 99.0% | 498.40 | 100 MG
CX-6258 hydrochloride is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively. For research use only. We do not sell to patients.
- Potent and kinase selective pan-Pim kinases inhibitor.
- Inhibits phosphorylation of pro-survival proteins Bad and 4E-BP1 at specific Pim kinase sites.
- Exhibits robust in vivo efficacy in Pim kinases driven tumor models.