Aminophenols
Medchemexpress LLC Cal-130 hydrochloride | 1431697-78-7 | 98.7% | 462.93 g/mol | C23H23ClN8O | 10 MG
Cal-130 hydrochloride is the hydrochloride salt of a small-molecule inhibitor selective for PI3Kδ (p110δ) and PI3Kγ (p110γ). It is supplied as a solid research reagent and shows low-nanomolar potency against its primary targets, with weaker activity toward other PI3K isoforms.
- Selective inhibition of PI3Kδ and PI3Kγ, low-nanomolar IC50 values
- Demonstrates activity against additional PI3K isoforms at higher concentrations
- High chemical purity suitable for in vitro and preclinical research
- Supplied as a solid, with common pack sizes suitable for laboratory studies
- Provided with documentation that includes molecular formula, molecular weight, and CAS number
Medchemexpress LLC Nefopam (hydrochloride) | 23327-57-3 | 99.9% | 1 ML
Nefopam hydrochloride is a centrally-acting, non-opioid analgesic drug used for the relief of moderate to severe pain. It targets β-catenin protein levels in mesenchymal cells both in-vitro and in-vivo. This non-opioid, non-steroidal analgesic is derived from benzoxazocine. Constitutively elevated β-catenin leads to delayed and fibrous fracture repair, and Nefopam inhibits β-catenin mediated signaling during skin wound repair.
- Centrally-acting, non-opioid analgesic
- Relieves moderate to severe pain
- Targets β-catenin protein levels
- Inhibits β-catenin mediated signaling
Cayman Chemical N-formyl-2-AmInophenol 100mg
A bacterial secondary metabolite with antioxidant activity; scavenges DPPH radicals in a cell-free assay (IC50 = 3.23 UG/ml); has been used in the synthesis of compounds with antibacterial and antifungal activities
![eMolecules 2075-45-8 | 4-Bromopyrazole | Ambeed | MFCD00075602 | 146.975 | C3H3BrN2 | 98.000 | Brc1cn[nH]c1 | 1000g | 525129320](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000491465.jpg-250.jpg)
eMolecules 2075-45-8 | 4-Bromopyrazole | Ambeed | MFCD00075602 | 146.975 | C3H3BrN2 | 98.000 | Brc1cn[nH]c1 | 1000g | 525129320
4-Bromopyrazole | Ambeed | 2075-45-8 | MFCD00075602 | 146.975 | C3H3BrN2 | 98.000 | Brc1cn[nH]c1 | 1000g | 525129320
Medchemexpress LLC Riluzole hydrochloride | 850608-87-6 | MFCD02262214 | 99.9% | 100 MG
Riluzole hydrochloride is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
- Anticonvulsant agent
- Use-dependent Na+ channel blocker
- Inhibits GABA uptake
- Targets sodium channel
- IC50 of 43 μM (GABA receptor)
Medchemexpress LLC Scopine hydrochloride | 85700-55-6 | 99.7% | 1 ML
Scopine hydrochloride, also known as 6,7-Epoxytropine hydrochloride, is a metabolite of Scopolamine and a brain-targeting compound. It significantly increases the brain exposure of Chlorambucil and enhances its anti-glioma activity. It can be utilized in targeted therapy research for brain gliomas.
- Metabolite of Scopolamine
- Brain-targeting compound
- Increases brain exposure of Chlorambucil
- Enhances anti-glioma activity
- Suitable for targeted therapy research for brain gliomas
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.2% | 10 MG
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It demonstrates broad antiviral activities against various viruses, including human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. Its antiviral spectrum extends to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. This compound is suitable for research related to infection.
- Selective inhibitor of CDK7
- Inhibits human cytomegalovirus (HCMV) replication
- Shows broad antiviral activities against multiple virus families
- Exhibits anti-proliferative activity against human fibroblast primary cultures
- Interferes with virus-induced Rb phosphorylation
- Demonstrates promising pharmacokinetic properties in CD1 mice
TARGETMOL CHEMICALS INC CB-5083 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CB-5083 is a potent selective and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM). purity: 99%
eMolecules 2-(4-Tolyl)-4-(4-hydroxyphenyl)thiazole | 1500577-50-3 | MFCD27919676 | 1g
Oakwood Chemical | 2-(4-Tolyl)-4-(4-hydroxyphenyl)thiazole | 1g | 537706252 | 098246 | | 1500577-50-3 | MFCD27919676 | 267.350 | C16H13NOS
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Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.2% | 50 MG
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. This compound demonstrates broad antiviral activities against Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. It is suitable for research related to infection.
- Selective inhibitor of CDK7
- Inhibits human cytomegalovirus (HCMV) replication
- Broad antiviral activities against various viruses
- Suitable for infection research
- Exhibits anti-proliferative activity in human fibroblasts
- Demonstrates good oral bioavailability and half-life in vivo
Cayman Chemical N-formyl-2-AmInophenol 500mg
A bacterial secondary metabolite with antioxidant activity; scavenges DPPH radicals in a cell-free assay (IC50 = 3.23 UG/ml); has been used in the synthesis of compounds with antibacterial and antifungal activities
Chemscene ChemScene | (S)-Ethyl 2-ethoxy-3-(4-hydroxyphenyl)propanoate | 250MG | CS-0151952 | 0.98 | 222555-06-8| MFCD06796580 | 238.28
ChemScene | (S)-Ethyl 2-ethoxy-3-(4-hydroxyphenyl)propanoate | 250MG | CS-0151952 | 0.98 | 222555-06-8| MFCD06796580 | 238.28
TARGETMOL CHEMICALS INC E7016 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. E7016 (GPI 21016) is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo. purity: 98%