Aminophenols
Medchemexpress LLC CBL0137 hydrochloride (Curaxin-137 hydrochloride) | 1197397-89-9 | 99.7% | 372.89 | 100 MG
CBL0137 hydrochloride (Curaxin-137 hydrochloride) | 1197397-89-9 | 99.7% | 372.89 | 100 MG
Medchemexpress LLC Metixene hydrochloride hydrate | 7081-40-5 | ≥95.0% | 5MG
Metixene hydrochloride hydrate | 7081-40-5 | ≥95.0% | 5MG
Medchemexpress LLC CBL0137 hydrochloride | 1197397-89-9 | 99.7% | 372.89 g/mol | C21H25ClN2O2 | 10 MG
CBL0137 hydrochloride is a research-grade small molecule that inhibits the histone chaperone FACT, activates p53, and suppresses NF-κB signaling. It is used in preclinical studies to probe chromatin regulation and anticancer mechanisms in cell-based and biochemical assays.
- Inhibits the histone chaperone FACT.
- Activates p53 in cell-based assays (IC50 ≈ 0.37 μM).
- Inhibits NF-κB signaling in cell-based assays (IC50 ≈ 0.47 μM).
- High chemical purity, typically reported as 99.7%.
- Available as solid packs and as a DMSO solution for in vitro use.
- Suitable for mechanistic studies, pathway modulation, and preclinical cancer research.
Medchemexpress LLC Zymostenol-d7 | 2260669-19-8 | 99.9% | 393.70 | 1 MG
Zymostenol-d7 is deuterium labeled 5a-Cholest-8-en-3b-ol.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC MRL-494 (hydrochloride) | 2699937-04-5 | 98.6% | 25 MG
MRL-494 hydrochloride is an antibacterial agent that acts as an inhibitor of β-barrel assembly machine A (BamA). It is impervious to efflux and the outer membrane permeability barrier, effectively inhibiting both Gram-positive and Gram-negative bacteria. The agent lethally disrupts the cytoplasmic membrane and inhibits outer membrane protein biogenesis by targeting BamA.
- Impervious to efflux and outer membrane permeability barrier
- Inhibits both Gram-positive and Gram-negative bacteria
- Lethally disrupts cytoplasmic membrane
- Inhibits outer membrane protein biogenesis
Medchemexpress LLC Ski V | 24418-86-8 | MFCD07772193 | 99.0% | 254.24 g/mol | C15H10O4 | 5 MG
SKI V is a small-molecule sphingosine kinase inhibitor reported to induce apoptosis and exhibit antitumor activity in vitro. The compound is supplied as a powder for laboratory research, with molecular formula C15H10O4 and molecular weight 254.24 g/mol. Solubility and activity data support formulation in DMSO and mixed aqueous vehicles for cell-based studies.
- Inhibits sphingosine kinase and PI3K signaling.
- Demonstrates in vitro activity (IC50 ≈ 2 μM for GST-hSK).
- Reported IC50 values for additional targets provide selectivity context.
- Supplied as a powder suitable for laboratory handling and storage.
- Soluble in DMSO (~50 mg/mL) and formulatable in aqueous vehicles with co-solvents.
- Molecular weight 254.24 g/mol; chemical formula C15H10O4.
- Intended for research use only.
Medchemexpress LLC Metixene hydrochloride hydrate | 7081-40-5 | 99.9% | 1 ML
Metixene hydrochloride hydrate is supplied as a 10 mM solution in DMSO for research use. It is the hydrochloride salt of metixene, an anticholinergic and antiparkinsonian agent, provided in a 1 mL vial.
- Ready-to-use 10 mM solution in DMSO.
- Compact 1 mL vial for small-scale assays.
- High purity suitable for research applications.
- Molecular formula C20H26ClNOS, molecular weight 363.94 g/mol.
- Suitable for in vitro pharmacology and receptor studies.
Medchemexpress LLC PZ703b hydrochloride | 2471970-56-4 | 99.2% | 1636.90 | 1 MG
PZ703b hydrochloride | 2471970-56-4 | 99.2% | 1636.90 | 1 MG
Medchemexpress LLC CX-6258 hydrochloride hydrate | 1353858-99-7 | 99.2% | 516.42 | 25 MG
CX-6258 hydrochloride hydrate is a potent and selective pan-Pim kinases inhibitor. It effectively inhibits Pim-1, Pim-2, and Pim-3, making it suitable for research into cancer and metabolic diseases.
- Potent and kinase selective pan-Pim kinases inhibitor
- Inhibits Pim-1 (IC50: 5 nM), Pim-2 (IC50: 25 nM), and Pim-3 (IC50: 16 nM)
- Causes dose-dependent inhibition of phosphorylation of pro-survival proteins, Bad and 4E-BP1
- Diminishes steady-state levels of ectopic NKX3.1 in PC3 cells
- Exhibits robust in vivo efficacy in Pim kinases driven tumor models
- Achieves 45% tumor growth inhibition at 50 mg/kg and 75% at 100 mg/kg in vivo
Medchemexpress LLC Riluzole hydrochloride | 850608-87-6 | 99.9% | 10 MM * 1 ML
Riluzole hydrochloride is an anticonvulsant agent that functions as a use-dependent Na+ channel blocker. It can also inhibit GABA uptake with an IC50 of 43 μM. This product is intended for research use only.
- Anticonvulsant agent
- Functions as a use-dependent Na+ channel blocker
- Inhibits GABA uptake
Medchemexpress LLC HY-15508 5mg Medchemexpress, JANEX-1 CAS:202475-60-3 Purity:>98%
Medchemexpress, HY-15508 5mg JANEX-1 CAS:202475-60-3 JANEX-1 (WHI-P131) is a potent and specific JAK3 inhibitor (estimated Ki=2.3 μM). JANEX-1 (WHI-P131) shows potent JAK3-inhibitory activity (IC50 of 78 μM), does not inhibit JAK1 and JAK2. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.