Aminophenols
TARGETMOL CHEMICALS INC TALOTREXIN AMMONIUM 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Talotrexin ammonium is a non-polyglutamic acid antifolate. Talotrexin ammonium inhibits tumor growth by targeting dihydrofolate reductase (DHFR) thereby improving anti-tumor activity in a wide range of cancer models helping to inhibit tumor growth. purity: 97%
TARGETMOL CHEMICALS INC CGS 15435 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CGS 15435 is a potent thromboxen (TxA2) synthetase inhibitor (IC50 1 nM). CGS 15435 acts on PGI2 synthase cyclooxygenase and liposynthase with much less selectivity than on thromboxin synthase. purity: 99%
Apexbio Technology LLC BODIPY 581/591 C11(Synonyms: BODIPY-C11, BODIPY 581/591 lipid peroxidation sensor, BODIPY 581/591 undecanoic acid), 1mg, CAS: 217075-36-0.
BODIPY 581/591 C11 (CAS 217075-36-0) is a cell-permeable ratiometric fluorescent probe used to detect lipid peroxidation and evaluate antioxidant capacity in biological membranes or live cells Under reduced conditions it displays red fluorescence at excitation/emission wavelengths of approximately 581/591 nm Upon oxidation of its polyunsaturated butadienyl segment by reactive oxygen species (e g hydroxyl radicals peroxynitrite) emission shifts from 590 nm to 510 nm resulting in green fluorescence (excitation/emission around 488/510 nm) Its specificity and photostability make BODIPY 581/591 C11 suitable for quantifying lipid oxidative stress in biomedical research
Medchemexpress LLC Dtagv-1 hydrochloride | 2624313-16-0 | 99.9% | C68H91ClN6O14S | 25 MG
dTAGV-1 hydrochloride is a potent and selective PROTAC degrader designed for FKBP12F36V-tagged proteins. This compound is capable of inducing degradation of FKBP12F36V-Nluc both in vitro and in vivo.
- Potent and selective degrader of FKBP12F36V-tagged proteins
- Induces degradation of FKBP12F36V-Nluc in vivo
- Composed of a Target Protein Ligand, a Linker, and a VHL Ligand
- Intended for research use only
Medchemexpress LLC Verbenalin | 548-37-8 | MFCD00017414 | 99.9% | 388.37 | C17H24O10 | 10 MG
Verbenalin is a terpenoid glycoside research compound reported to have anti-inflammatory, antiviral, and neuroprotective activities. It is supplied as a white to off-white solid and is used in biological research on inflammatory pathways, neuroprotection, and viral protein interactions. Store and handle according to the supplier's recommended conditions.
Medchemexpress LLC Oxysanguinarine | 548-30-1 | 1 MG
Oxysanguinarine is a protoberberine alkaloid derived from Meconopsis simplicifolia. It exhibits antimalarial activity and is primarily intended for laboratory research and the manufacture of substances.
- Purity: 99.34%
- Molecular formula: C20H13NO5
- Molecular weight: 347.32
- Appearance: Solid
- Color: White to off-white
- Classified as a protoberberine alkaloid
- Derived from Meconopsis simplicifolia
- Exhibits antimalarial activity against Plasmodium
- Shows antiproliferative activity against A549 and NCI-H1975 cells
- Stable under recommended storage conditions
- Recommended storage: -20°C, protect from light
- Storage in solvent: -80°C for 6 months, or -20°C for 1 month (protect from light)
- Shipping: Room temperature if less than 2 weeks
TARGETMOL CHEMICALS INC SMARCA-BD LIGAND 1 FOR P 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2 the BAF ATPase subunit based on the Protac technology for degrading SMARCA2purity: 100%
Medchemexpress LLC ICCB-19 hydrochloride | 1803605-68-6 | 99.3% | 291.84 | 25 MG
ICCB-19 hydrochloride is an indirect inhibitor of RIPK1 kinase activity and a TRADD (TNFRSF1A associated via death domain) inhibitor. It functions by binding with the N-terminal domain of TRADD (TRADD-N), which disrupts its binding to both TRADD-C and TRAF2. This compound effectively induces autophagy and the degradation of long-lived proteins.
- Inhibits Bortezomib-induced apoptosis and RIPK1-dependent apoptosis (RDA) with an IC50 of about 1 μM.
- Promotes autophagy via K63-linked ubiquitination of beclin 1.
- Reduces inflammatory responses in Tradd-/- mice.
- Reduces expression of TNF-induced inflammatory target gene products and cytokines.
TARGETMOL CHEMICALS INC GLPG0492 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GLPG0492 is a novel selective androgen receptor modulator. After oral dosing it showed anabolic activity on muscle strongly dissociated from the androgenic activity on the prostate. purity: 98%
Medchemexpress LLC DI-82 | 1638148-50-1 | >98.0% | 510.65 | 25 MG
DI-82 is a potent deoxycytidine kinase (dCK) inhibitor with an IC50app of 27.8 nM and Kiapp of 9.2 nM. It exhibits antitumor activity, making it suitable for various research applications in oncology and cell biology.
- Potent deoxycytidine kinase (dCK) inhibitor
- Exhibits antitumor activity
- IC50 of 3.7 nM in CCRF-CEM acute lymphoblastic leukemia cells
- NADPH-dependent CLint of 22.7 μL/min·mg and T1/2 of 102 minutes in microsomal liver clearance assay
- Completely blunts the ability of decitabine to bind human thymidylate synthase (TS)
Medchemexpress LLC Riluzole hydrochloride | 850608-87-6 | MFCD02262214 | 99.9% | 100 MG
Riluzole hydrochloride is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
- Anticonvulsant agent
- Use-dependent Na+ channel blocker
- Inhibits GABA uptake
- Targets sodium channel
- IC50 of 43 μM (GABA receptor)
eMolecules 487-68-3 | Mesitaldehyde | Ambeed | MFCD00003341 | 148.205 | C10H12O | 95.000 | Cc1cc(C)c(C=O)c(C)c1 | 1000g | 600833343
Mesitaldehyde | Ambeed | 487-68-3 | MFCD00003341 | 148.205 | C10H12O | 95.000 | Cc1cc(C)c(C=O)c(C)c1 | 1000g | 600833343