Aminophenols
Medchemexpress LLC CX-6258 hydrochloride hydrate | 1353858-99-7 | 99.2% | 516.42 | 1 ML
CX-6258 hydrochloride hydrate is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively.
- Potent and kinase selective pan-Pim kinases inhibitor
- IC50s of 5 nM (Pim-1), 25 nM (Pim-2), 16 nM (Pim-3)
- Causes dose-dependent inhibition of the phosphorylation of pro-survival proteins Bad and 4E-BP1 at specific Pim kinase sites (S112, S65, T37/46)
- Diminishes steady-state levels and reduces half-life of ectopic NKX3.1 in PC3 cells
- Exhibits robust in vivo efficacy in two Pim kinases driven tumor models (e.g., MV-4-11 xenograft models in nude mice)
Medchemexpress LLC RS 67333 (hydrochloride) | 168986-60-5 | MFCD00938576 | 99.7% | 389.36 | C19H30Cl2N2O2 | 25 MG
RS 67333 hydrochloride is a research-grade, selective 5-HT4 receptor partial agonist used in preclinical and in vitro neuroscience studies to investigate serotonergic signaling and neuroprotective mechanisms.
- Potent, selective 5-HT4 receptor partial agonist for neuroscience research.
- High purity, 99.7% (as listed by manufacturer).
- Molecular weight 389.36 g/mol; formula C19H30Cl2N2O2.
- Solid, light yellow to yellow appearance supplied as a dry powder.
- Storage: 4°C, sealed and away from moisture; in solvent store at -80°C for long-term.
- Available as a 25 MG vial for laboratory use.
- CAS number 168986-60-5.
Medchemexpress LLC CGP71683 hydrochloride | 192322-50-2 | MFCD07783999 | 99.4% | 512.07 g/mol | C26H30ClN5O2S | 1 ML
CGP71683 hydrochloride is a selective, non-peptide neuropeptide Y (NPY) Y5 receptor antagonist (Ki = 1.3 nM) commonly used in receptor pharmacology and signaling research. It demonstrates substantially reduced activity at Y1 and Y2 receptors and is supplied both as a solid and as a pre-made DMSO solution for ready-to-use assays.
- Selective NPY Y5 receptor antagonist (Ki = 1.3 nM).
- High selectivity over Y1 and Y2 receptors.
- Available as solid or 10 mM solution in DMSO, 1 mL.
- High purity suitable for research applications.
- Intended for receptor pharmacology and signaling studies.
Medchemexpress LLC CSRM617 hydrochloride | 1353749-74-2 | 100.0% | 5MG
CSRM617 hydrochloride | 1353749-74-2 | 100.0% | 5MG
Medchemexpress LLC OATD-02 hydrochloride | 2146132-73-0 | 99.9% | 308.61 g/mol | C12H26BClN2O4 | 10 MG
OATD-02 hydrochloride is the hydrochloride salt form of an orally active, competitive, reversible, noncovalent dual inhibitor of arginase 1 and arginase 2, intended for preclinical cancer research. It is supplied as a high-purity, water-soluble solid suitable for in vitro and in vivo studies.
- High purity: 99.9%.
- White to off-white solid physical form.
- High aqueous solubility: 250 mg/mL in water (may require ultrasonic).
- Dual arginase 1 and 2 inhibitory activity for tumor immunology research.
- Available in small research pack sizes for preclinical use.
eMolecules 125697-91-8 | Medchem Express | Lavendustin B | 5mg | 596608002 | HY-108935 | MFCD00133446 | 365.385 | C21H19NO5
Medchem Express | S-acetyl-PEG4-propargyl | 50mg | 752823151 | HY-141350 | 1422540-88-2 | MFCD29764347 | 290.370 | C13H22O5S
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eMolecules Building Block Tool<|a>
eMolecules 51-78-5 | 4-Aminophenol hydrochloride | Combi-Blocks | MFCD00012996 | 145.590 | C6H8ClNO | 97.000 | Cl.Nc1ccc(O)cc1 | 25g | 537622500
4-Aminophenol hydrochloride | Combi-Blocks | 51-78-5 | MFCD00012996 | 145.590 | C6H8ClNO | 97.000 | Cl.Nc1ccc(O)cc1 | 25g | 537622500
Medchemexpress LLC MRT-83 (hydrochloride) | 1359944-60-7 | 99.6% | 575.05 | 25 MG
MRT-83 (hydrochloride) is a potent antagonist of the Smoothened (Smo) receptor. It inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. MRT-83 (hydrochloride) has potential for researching cancer disease.
- Potent antagonist of Smoothened (Smo) receptor.
- Inhibits the Hedgehog (Hh) signaling pathway.
- Inhibits BODIPY-cyclopamine binding to human Smo.
- Potential for researching cancer disease.
Medchemexpress LLC Nefopam (hydrochloride) | 23327-57-3 | 99.9% | 500 MG
Nefopam hydrochloride is a centrally-acting, non-opioid analgesic drug used for the relief of moderate to severe pain. It also targets β-catenin protein levels in mesenchymal cells both in-vitro and in-vivo.
- Functions as a pain reliever for moderate to severe pain.
- Is a non-opioid drug.
- Targets β-catenin protein levels in mesenchymal cells.
Medchemexpress LLC LMP744 hydrochloride | 308246-57-3 | 488.92 | 5 MG
LMP744 hydrochloride (MJ-III65 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor exhibiting antitumor activity. It is a solid, light brown to brown in appearance, with a purity of 99.08%.
- DNA intercalator
- Topoisomerase I (Top1) inhibitor
- Exhibits antitumor activity
- Induces dose-dependent accumulation of cells in the S and G2 phases of the cell cycle
- Moderately active against human A253 and FaDu tumor xenografts in vivo