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R-1 Methanandamide Phosphate is a water-soluble prodrug analog of arachidonylethanolamide (AEA), an endogenous cannabinoid compound. It is intended for research use only and not for patient use.
Water-soluble prodrug analog of arachidonylethanolamide (AEA)
Endogenous cannabinoid compound
Appears as a viscous liquid
Yellow to brown color
For research use only
Store at -20°C, protected from light
When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
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R-1 Methanandamide Phosphate is a water-soluble phosphate prodrug analog of arachidonylethanolamide (AEA), an endogenous cannabinoid. Provided for research use, it enables aqueous handling and delivery compared with the parent lipid AEA and is supplied both as a solid and as ready-to-use DMSO solution for biochemical and cellular studies.
Water-soluble phosphate prodrug of arachidonylethanolamide (AEA).
Facilitates aqueous handling and administration compared with lipid AEA.
Suitable for in vitro research on cannabinoid receptor signaling.
Available as powder and as 10 mM solution in DMSO.
High purity reported (≥98%).
Molecular weight 441.54 g·mol⁻¹; formula C23H40NO5P.
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A sulfate conjugate of p-cresol; increases migration and proliferation of isolated rat aortic VSMCs at 500 µM; increases aortic atherosclerotic plaques lesion area in nephrectomized ApoE-/- mice fed a high-fat diet when administered at 100 mg/kg per day via the drinking water; serum levels are increased in patients with advanced stage chronic kidney disease and positively associated with vascular calcification
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A sulfate conjugate of p-cresol; increases migration and proliferation of isolated rat aortic VSMCs at 500 µM; increases aortic atherosclerotic plaques lesion area in nephrectomized ApoE-/- mice fed a high-fat diet when administered at 100 mg/kg per day via the drinking water; serum levels are increased in patients with advanced stage chronic kidney disease and positively associated with vascular calcification
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A sulfate conjugate of p-cresol; increases migration and proliferation of isolated rat aortic VSMCs at 500 µM; increases aortic atherosclerotic plaques lesion area in nephrectomized ApoE-/- mice fed a high-fat diet when administered at 100 mg/kg per day via the drinking water; serum levels are increased in patients with advanced stage chronic kidney disease and positively associated with vascular calcification
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A sulfate conjugate of p-cresol; increases migration and proliferation of isolated rat aortic VSMCs at 500 µM; increases aortic atherosclerotic plaques lesion area in nephrectomized ApoE-/- mice fed a high-fat diet when administered at 100 mg/kg per day via the drinking water; serum levels are increased in patients with advanced stage chronic kidney disease and positively associated with vascular calcification
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Potassium p-nitrophenyl sulfate is a chromogenic substrate used for arylsulfatase. It is released by arylsulfonase cleavage, allowing the activity of arylsulfonase to be quantitatively determined by colorimetric detection at 400 nm.
Chromogenic substrate for arylsulfatase
Supports quantitative determination of arylsulfonase activity
Solid appearance
Off-white to yellow color
Soluble in H2O at 25 mg/mL
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p-APMSF is used as a serine protease activity inhibitor Since it specifically suppresses the activity of blood coagulation factor Xa it is used for the study of blood coagulation mechanism Compared to DFP diisopropylfluorophosphate it is easy to handle because it is powder and soluble to water In addition it is reported that serine protease inhibitory activity is several hundred times higher than DFP and PMSF It inhibits the activity of trypsin thrombin plasmin kallikrein and others It does not affect chymotrypsin or acetylcholinesterase For research use only RUO
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Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant the water-soluble N-phosphorylated prodrug of aprepitant with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis. purity: 98%
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C-Type Natriuretic Peptide (1-53), human TFA is the 1-53 fragment of C-Type Natriuretic Peptide. This natriuretic peptide family peptide is involved in the maintenance of electrolyte-fluid balance and vascular tone.
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Atrial natriuretic peptide (1-28), human, porcine, biotin-labeled, is one of three mammalian natriuretic peptides (NPs) and has endocrine effects on fluid homeostasis and blood pressure. It has potential for cardiovascular diseases research.