Cresols
Akina Inc Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-carboxylic acid endcap (per 100mg)
PLGA-PEG-COOH LG 50:50 (Mw ~40,000:5,000 Da) Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-carboxylic acid endcap (per 100mg)
Akina Inc Poly(lactide-co-glycolide)-b-Poly(ethylene glycol)-b-Poly(lactide-co-glycolide) (per g)
PLGA-PEG-PLGA (Mw ~1,700:1,500:1,700 Da) LA:GA 3:1 Poly(lactide-co-glycolide)-b-Poly(ethylene glycol)-b-Poly(lactide-co-glycolide) (per g)
Akina Inc Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) (per g)
PLGA-PEG-PLGA (Mw ~1,750-1,500-1,750 Da) LA:GA 15:1 Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) (per g)
Medchemexpress LLC Methoxy polyethylene glycol (mPEG) 13 carboxylic acid | 2170098-33-4 | MFCD28385486 | 95.0% | 632.74 g/mol | C28H56O15 | 1 G
m-PEG13-acid is a methoxy-terminated polyethylene glycol (PEG) linker bearing a terminal carboxylic acid. It is used as a flexible, hydrophilic spacer for bioconjugation and PEGylation; the carboxylic acid can be activated for amide formation with primary amines, making it suitable for linker construction in medicinal chemistry and PROTAC synthesis.
- Provides terminal carboxylic acid for facile amide coupling to primary amines
- Methoxy-terminated (monofunctional) PEG to limit crosslinking
- Flexible, hydrophilic spacer suitable for PEGylation and linker design
- Molecular weight ≈ 632.74 g/mol; formula C28H56O15
- Common applications include bioconjugation and PROTAC linker synthesis
- Supplied as a powder; follow supplier storage and handling guidance
Medchemexpress LLC M-PEG37-acid | 2924199-92-6 | N/A | >96.0% | C76H152O39 | 10MG
m-PEG37-acid is a carboxyl-terminated methoxy-polyethylene glycol (mPEG) linker with an average chain length of approximately 37 ethylene glycol units. It is designed for use as a PEG-based PROTAC linker or spacer in medicinal chemistry and bioconjugation workflows, providing hydrophilicity and flexible spacing between binding motifs while offering a reactive carboxyl terminus for conjugation.
- Carboxyl-terminated mPEG linker with ~37 ethylene glycol units.
- Enhances solubility and hydrophilicity of conjugates.
- Provides flexible spacer for PROTAC synthesis and bioconjugation.
- Terminal carboxyl enables standard amide or ester coupling reactions.
- Reported purity greater than 96% for research applications.
Medchemexpress LLC m-PEG5-acid | 81836-43-3 | 95.0% | 280.31 g/mol | C12H24O7 | 5 G
m-PEG5-acid is a methoxy-terminated polyethylene glycol linker (five ethylene glycol units) with a terminal carboxylic acid that provides a short, flexible spacer for PROTAC and bioconjugation chemistry.
- provides a short, flexible peg spacer for linker design
- contains a terminal carboxylic acid for coupling reactions
- methoxy-terminated to cap one end and prevent further reaction
- useful in synthesis of PROTACs and other bioconjugates
- available in small laboratory pack sizes for research use
Medchemexpress LLC M-PEG10-acid | 2409969-94-2 | 98.0% | 500.58 | C22H44O12 | 25 MG
m-PEG10-acid is a non-cleavable polyethylene glycol (PEG) linker containing 10 ethylene glycol units. It is supplied as an oil and is used as a hydrophilic spacer in the synthesis of antibody-drug conjugates (ADCs) and proteolysis targeting chimeras (PROTACs).
- Non-cleavable 10-unit PEG structure suitable for linker applications.
- Molecular weight 500.58 g·mol⁻¹ and formula C22H44O12.
- Purity 98.0% by NMR.
- Storage at -20°C under nitrogen; in solvent: -80°C (6 months) or -20°C (1 month).
- Available in small research quantities, e.g., 25 mg.
Medchemexpress LLC M-PEG13-acid | 2170098-33-4 | 99.9% | 632.74 g/mol | C28H56O15 | 5 G
m-PEG13-acid is a methoxy polyethylene glycol (mPEG) linker bearing a terminal carboxylic acid. It functions as a hydrophilic spacer for bioconjugation and biochemical assays; the terminal carboxyl can be activated (for example with EDC or HATU) and coupled to primary amines to form stable amide bonds, while the PEG spacer enhances aqueous solubility.
Medchemexpress LLC M-PEG13-acid | 2170098-33-4 | MFCD28385486 | >95.0% | 632.74 g·mol⁻¹ | C28H56O15 | 100 MG
m-PEG13-acid is a polyethylene glycol (PEG) linker bearing a terminal carboxylic acid used in bioconjugation and PEGylation chemistry. It provides a hydrophilic spacer that facilitates formation of amide bonds to primary amines after activation, improving solubility and flexibility of conjugates. Typical identifiers: molecular weight ~632.74 g·mol⁻¹, formula C28H56O15, CAS 2170098-33-4, purity >95.0%.
- Acts as a hydrophilic spacer for bioconjugation.
- Contains a terminal carboxylic acid for amide bond formation with primary amines.
- Improves solubility and flexibility of conjugated molecules.
- Compatible with common coupling agents such as EDC and HATU.
- Supplied at >95.0% purity for research applications.
Medchemexpress LLC m-PEG2-Tos | 50586-80-6 | MFCD13184964 | 97.0% | 274.33 | C12H18O5S | 5 G
m-PEG2-Tos is an uncleavable polyethylene glycol (PEG) linker used for assembling antibody-drug conjugates (ADCs) and as a PEG-based linker for proteolysis targeting chimeras (PROTACs). It has a methoxy-capped PEG spacer and a tosylate reactive terminus for conjugation to nucleophiles.
- Used as an uncleavable ADC linker for attaching cytotoxins to antibodies.
- Suitable as a PEG-based PROTAC linker for connecting protein ligands.
- Methoxy-capped PEG spacer with a tosylate reactive end for conjugation.
- Reported molecular weight 274.33 and formula C12H18O5S.
- High reported purity (about 97%).
- Available in multiple package sizes for synthetic workflows.
Medchemexpress LLC m-PEG10-acid | 2409969-94-2 | >98.0% | 500.58 g/mol | C22H44O12 | 50 MG
m-PEG10-acid is a 10-unit methoxy polyethylene glycol (PEG) carboxylic acid used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as a PEG-based PROTAC linker. It provides a hydrophilic spacer terminating in a carboxyl group for covalent coupling to amines or other nucleophiles.
- Provides a 10-unit PEG spacer with terminal carboxyl for conjugation.
- Suitable as a non-cleavable ADC linker and as a PROTAC linker.
- Improves solubility and reduces aggregation as a hydrophilic spacer.
- Molecular weight approximately 500.58 g/mol.
- Reported purity greater than 98.0%.
- Available in small laboratory pack sizes such as 50 MG.
Medchemexpress LLC m-PEG13-acid | 2170098-33-4 | MFCD28385486 | >95.0% | 632.74 g·mol⁻¹ | C28H56O15 | 500 MG
m-PEG13-acid is a methoxy-terminated polyethylene glycol (PEG) linker bearing a terminal carboxylic acid. It provides a hydrophilic spacer and a reactive carboxyl group for conjugation chemistry, facilitating amide bond formation with primary amines. The product is supplied as a powder for use in chemical synthesis and bioconjugation.
- Provides a methoxy-terminated PEG13 spacer to increase solubility and reduce steric hindrance.
- Terminal carboxylic acid enables amide bond formation with primary amines (EDC/DCC/HATU coupling).
- Suitable for bioconjugation and linker assembly in medicinal chemistry and biochemical research.
- Supplied as a powder for straightforward weighing and handling.
- Typical supplier purity >95% for synthetic applications.
Medchemexpress LLC m-PEG2-acid | 149577-05-9 | >98% | 1 G
m-PEG2-acid is a polyethylene glycol (PEG)-based PROTAC linker. It is primarily used in the synthesis of Proteolysis-Targeting Chimeras (PROTACs), which are molecules designed to exploit the intracellular ubiquitin-proteasome system. PROTACs achieve selective degradation of target proteins by linking them to an E3 ubiquitin ligase.
- PEG-based PROTAC linker
- Facilitates the synthesis of PROTACs
- Molecular weight of 148.16
- Chemical formula C6H12O4
- Appears as a colorless to light yellow liquid
- Density of 1.098 ±0.06 g/cm³
- Storage for pure form: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month