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Filtered Search Results
Medchemexpress LLC Noggin Human CHO 100ug
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Recombinant human Noggin protein, expressed in CHO cells and supplied as a lyophilized, tag-free powder for in vitro research use. Noggin binds BMP-2/4/7 to antagonize BMP signaling and is provided with high purity and formulation components to support stability and storage.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Apparent molecular weight ~27-36 kDa due to glycosylation.
- Lyophilized formulation with trehalose for improved stability.
- Mammalian expression (CHO) for relevant post-translational modifications.
- Suitable for in vitro research applications; not for clinical use.
- Multiple pack sizes available, including 100 μg.
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Medchemexpress LLC Advanced glycation end products | 1 MG
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Advanced glycation end products (AGEs) are stable compounds formed by non-enzymatic reactions of reducing sugars with proteins, lipids, or nucleic acids. They are frequently utilized as a target for assessing the inhibitory effects of anti-glycosylation compounds.
- Used for research purposes
- Supplied as a liquid
- Light yellow to yellow appearance
- Concentration of 50 mg/mL
- Formulated in 0.01 M PBS, pH 7.4
- Store at -20°C for 2 years
- Not classified as a hazardous substance or mixture
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Medchemexpress LLC Highly purified type III collagen, from bovine skin | 90.0% | 300000.00 | 1 MG
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Highly purified Type III collagen, from bovine skin, is an immune grade collagen derived from bovine skin. It is designed to stimulate the animal's immune system to produce specific antibodies against this collagen and also functions as a substrate for hydrolysis by Matrix Metalloproteinases (MMPs).
- Immune grade collagen
- Derived from bovine skin
- Stimulates specific antibody production
- Substrate for Matrix Metalloproteinase (MMP) hydrolysis
- For research use only
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Bioss Klebsiella sp.
Klebsiella sp
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Medchemexpress LLC DUP-532 | 100MG
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DUP-532 | 100MG
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eMolecules Oakwood Chemicals Sodium triacetoxyborohydride 1kg 480132049 044864 0 000 56553-60-7 MFCD00012211 211 940 C6H10BNaO6
Oakwood Chemicals Sodium triacetoxyborohydride 1kg 480132049 044864 0 000 56553-60-7 MFCD00012211 211 940 C6H10BNaO6
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Medchemexpress LLC N-[4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]phenyl]-1-(2-furanylmethyl)-5-oxo-pyrrolidinecarboxamide | 2784577-71-3 | MFCD00701047 | C24H19ClN4O4 | 1 ML
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RLX-33 is a potent, selective, and blood-brain barrier (BBB) penetrant relaxin family peptide 3 (RXFP3) antagonist. This compound blocks relaxin-3-induced ERK1/2 phosphorylation and can prevent the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats, making it suitable for metabolic syndrome research.
- Potent and selective RXFP3 antagonist
- Blood-brain barrier penetrant
- Blocks relaxin-3-induced ERK1/2 phosphorylation
- Attenuates R3/I5-induced feeding
- Good brain penetration
- Highly protein-bound in rat plasma
- Useful for metabolic syndrome research
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Cambridge Isotope Laboratories 1 2 4 7-TetraCN (PCN-34) (unlabeled) 100 ug/mL in nonane 1 2 mL
1 2 4 7-TetraCN (PCN-34) (unlabeled) 100 ug/mL in nonane 1 2 mL
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Apexbio Technology LLC Lansoprazole sodium 226904-00-3 10mM (in 1mL Ethanol)
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Lansoprazole sodium is a small-molecule inhibitor targeting gastric H /K -ATPase and several human cytochrome P450 (CYP) isoforms including CYP2C9 and CYP2C19 It is designed to inhibit acid secretion by selectively modulating H /K -ATPase activity in parietal cells and to modulate CYP-mediated metabolism pathways Lansoprazole sodium exerts its biological activity primarily through inhibition of its targets In human liver microsome studies it inhibits CYP2C9 and CYP2C19 with Ki values of approximately 21 M and 1 M respectively its inhibitory effect on CYP2D6 and CYP3A4 is weaker with IC values above 200 M Based on these pharmacological properties Lansoprazole sodium holds research potential in the investigation of gastric acid secretion disorders and drug drug interaction profiles involving CYP-mediated metabolism
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Medchemexpress LLC Sodium Glucoheptonate | 31138-65-5 | 98.0% | 248.16 | 25 G
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Sodium Glucoheptonate is used as a kit for radio-labeling with Tc-99m. Tc-99m glucoheptonate is a kidney- and brain-imaging agent, and can be used in brain-tumor detection. It exhibits rapid blood clearance and a quite stable blood level.
- Used as a kit for radio-labeling with Tc-99m
- Can be used in brain-tumor detection
- Exhibits rapid blood clearance
- Has a stable blood level
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Medchemexpress LLC 1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane | 35638-19-8 | >98% | C17H28O12 | 5 G
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1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- Purity >98%
- Solid appearance
- White to off-white color
- Molecular weight: 424.40
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Medchemexpress LLC Xalnesiran sodium | 2538784-49-3 | 95.9% | C664H814F17N231Na57O415P57S6 | 1 MG
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Xalnesiran sodium is a siRNA used for the study of chronic hepatitis B (HBV). It is intended for research use only and is not sold to patients.
- siRNA for chronic hepatitis B (HBV) studies
- Available in various unit sizes (1 mg, 5 mg, 10 mg, 25 mg, 50 mg)
- High purity (95.90%)
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Medchemexpress LLC OARV-771 | 2683008-37-7 | 98.8% | C49H59ClN8O8S2 | 25 MG
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OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. It shows DC50s of 6 nM for Brd4, 1 nM for Brd2, and 4 nM for Brd3. It also exhibits an antiproliferative effect with an EC50 value of 4 nM in MV4;11 cells.
- VHL-based BET degrader (PROTAC)
- Enhanced cell permeability
- Demonstrates DC50s of 6 nM for Brd4, 1 nM for Brd2, and 4 nM for Brd3
- Exhibits an antiproliferative effect with an EC50 value of 4 nM in MV4;11 cells
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Medchemexpress LLC HaloPROTAC-E | 2365478-58-4 | 98.76% | C39H56ClN5O8S | 1 MG
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HaloPROTAC-E is a potent Halo PROTAC degrader that reversibly induces degradation of two Halo-tagged endoplasmic reticulum-localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM. It significantly and selectively induces degradation of endogenous VPS34 complexes (VPS34, VPS15, Beclin1, and ATG14) labeled with Halo and inhibits autophagy.
- Potent Halo PROTAC degrader
- Reversibly induces degradation of Halo-tagged SGK3 and VPS34
- DC50 of 3-10 nM
- Significantly and selectively degrades endogenous VPS34 complexes
- Inhibits autophagy
- Rapid and complete depletion of Halo-tagged SGK3 in vitro
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Medchemexpress LLC L-Serine ethyl ester hydrochloride | 26348-61-8 | MFCD00012594 | ≥98.0% | 169.61 g/mol | C5H12ClNO3 | 100 G
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L-Serine ethyl ester hydrochloride is the ethyl ester hydrochloride salt of the amino acid L-serine. Supplied as a white to off-white solid with high purity, it is used as an amino acid derivative in peptide synthesis, biochemical studies, and related research applications.
- High purity ≥98.0% (NMR).
- White to off-white solid for easy handling and weighing.
- Suitable for peptide synthesis and biochemical studies.
- Hydrochloride salt form to improve solubility in polar solvents.
- Recommended storage at 4°C, protected from moisture.
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