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Filtered Search Results
eMolecules 367-27-1 | 2,4-Difluorophenol | Oakwood Chemical | MFCD00009715 | 130.094 | C6H4F2O | 98.000 | Oc1ccc(F)cc1F | 1g | 537662793
2,4-Difluorophenol | Oakwood Chemical | 367-27-1 | MFCD00009715 | 130.094 | C6H4F2O | 98.000 | Oc1ccc(F)cc1F | 1g | 537662793
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eMolecules 367-27-1 | 2,4-Difluorophenol | Accela ChemBio (ASD) | MFCD00009715 | 130.094 | C6H4F2O | 97.000 | Oc1ccc(F)cc1F | 10g | 510408906
2,4-Difluorophenol | Accela ChemBio (ASD) | 367-27-1 | MFCD00009715 | 130.094 | C6H4F2O | 97.000 | Oc1ccc(F)cc1F | 10g | 510408906
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eMolecules 367-27-1 | 2,4-Difluorophenol | ChemScene | MFCD00009715 | 130.094 | C6H4F2O | 98.000 | Oc1ccc(F)cc1F | 100g | 572239541
2,4-Difluorophenol | ChemScene | 367-27-1 | MFCD00009715 | 130.094 | C6H4F2O | 98.000 | Oc1ccc(F)cc1F | 100g | 572239541
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eMolecules 163734-01-8 | Ambeed | 2-Amino-45-difluorophenol | 1g | 490504208 | A129617 | MFCD03094185 | 145.109 | C6H5F2NO
Ambeed | (4S4S)-Di-tert-butyl 22-(cyclopropane-11-diyl)bis(45-dihydrooxazole-4-carboxylate) | 100mg | 771330817 | A1281557 | 2328084-27-9 | 380.441 | C19H28N2O6
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Medchemexpress LLC Edaravone | 89-25-8 | MFCD00003138 | 99.9% | C10H10N2O | 25 G
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Edaravone is a potent free radical scavenger and neuroprotective agent. It exhibits preventative and therapeutic effects against glutamate toxicity by reducing apoptosis and necrosis. It also inhibits MMP-9-related brain hemorrhage and ameliorates neuronal damage in brain ischemia. This compound is intended for research use only, supporting studies on neuroprotection and free radical scavenging.
- Strong free radical scavenger
- Inhibits MMP-9-related brain hemorrhage
- Demonstrates neuroprotective activity against H2O2-induced cell damage
- Shows neuroprotective activity against glutamate-induced toxicity
- Inhibits arachidonic acid and adenosine diphosphate-induced platelet aggregation
- Reduces astrogliosis and apoptosis
- Increases protein expression of TGF-β1, VEGF, and MMP9
- Suppresses TNF-α expression
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Medchemexpress LLC Menin-MLL inhibitor MI-2 | 1271738-62-5 | C18H25N5S2 | 1 ML
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Menin-MLL inhibitor MI-2 is a competitive and selective Menin-MLL interaction inhibitor. It effectively downregulates target genes like HOXA9 and MEIS1, leading to inhibition of leukemia cell proliferation and induction of apoptosis and differentiation. This compound shows promise in the research of MLL-rearranged acute leukemias, including AML and ALL, with an IC50 of 446 nM and a Ki value of 158 nM.
- Competitive and selective Menin-MLL interaction inhibitor
- Downregulates expression of target genes (HOXA9, MEIS1)
- Inhibits proliferation of leukemia cells
- Induces apoptosis and differentiation
- Promising for research of MLL-rearranged acute leukemias
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Medchemexpress LLC Carbamodithioic acid, N,N-diethyl-, sodium salt (1:1) | 148-18-5 | 25 G
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Ditiocarb sodium (Sodium diethyldithiocarbamate) is an orally active copper reagent. It exhibits various activities including antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. This compound is suitable for research in tumors, inflammatory, and immune-related diseases.
- Orally active copper reagent
- Exhibits antioxidation properties
- Shows chelation capabilities
- Has anti-tumor effects
- Provides immunomodulation
- Demonstrates anti-HIV properties
- Useful for research of tumors
- Applicable for inflammatory disease research
- Suitable for immune-related disease research
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Medchemexpress LLC 1H-1,2,4-Triazol-3-amine, 5-[4-[(2S,5S)-5-[(4-chlorophenyl)methyl]-2-methyl-4-morpholinyl]... | 2088453-21-6 | 99.9% | 390.91 | 1 ML
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OATD-01 is a highly potent, first-in-class, orally active, and selective chitinase inhibitor. It demonstrates low nanomolar activity towards CHIT1 and exhibits an excellent pharmacokinetic profile across multiple species. This compound shows significant antifibrotic efficacy in vivo and is being investigated for pulmonary fibrosis (IPF) research.
- Highly potent and selective chitinase inhibitor
- Low nanomolar activity towards CHIT1 (hCHIT1, IC50=23 nM)
- Excellent pharmacokinetic profile across multiple species
- Selective against a panel of off-targets
- Significant antifibrotic efficacy in vivo
- Suitable for pulmonary fibrosis (IPF) research
- Exhibits high affinity toward h/mCHIT1 and h/mAMCase
- Reduced lung fibrosis in animal models
- Clinical trials are underway for pulmonary sarcoidosis (Phase 2)
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Medchemexpress LLC N-Phenylbenzamide 100g
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N-Phenylbenzamide (N-Benzoylaniline) is a compound skeleton N-Phenylbenzamide can be used for the researches of cancer and infection such as enterovirus and cervical cancer[1][2]
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Medchemexpress LLC Pentanehydrazide (Valeric acid hydrazide) | 38291-82-6 | ≥95.0% | 116.16 | 100 G
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Pentanehydrazide, also known as Valeric acid hydrazide, is a biochemical reagent. It functions as an effective alkylating agent in the copper-catalyzed oxidative cyclization of N-arylacrylamides and participates in tandem acylation reactions.
- Acts as an effective alkylating agent.
- Involved in copper-catalyzed oxidative cyclization reactions.
- Participates in tandem acylation reactions.
- Suitable for research use only.
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Medchemexpress LLC Tamoxifen Citrate | 54965-24-1 | 99.88% | 10 G
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Tamoxifen Citrate is an orally active, selective estrogen receptor modulator (SERM) that blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. It is a potent Hsp90 activator, enhancing its molecular chaperone ATPase activity. Tamoxifen Citrate potently inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 values of 0.1 μM and 1.8 μM, respectively.
- Activates autophagy
- Induces apoptosis
- Can be used to induce gene knockout in CreER transgenic mice
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Medchemexpress LLC 2-acetyl-N-(4-(hexafluoro-2-hydroxypropan-2-yl)phenyl)-5-methylsulfonyl-dihydroisoindole carboxamide | 2101291-07-8 | 99.9% | 100MG
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2-acetyl-N-(4-(hexafluoro-2-hydroxypropan-2-yl)phenyl)-5-methylsulfonyl-dihydroisoindole carboxamide | 2101291-07-8 | 99.9% | 100MG
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Medchemexpress LLC Benzisothiazolone | 2634-33-5 | MFCD00044001, MFCD00127753 | 99.8% | 151.19 g/mol | C7H5NOS | 25 G
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Benzisothiazolone (1,2-benzisothiazol-3(2H)-one; CAS 2634-33-5) is a heterocyclic isothiazolone used as a biocide and preservative in industrial and laboratory contexts. It is supplied as a solid powder intended for formulation, analytical, and research use.
- Broad-spectrum antimicrobial activity against bacteria and fungi.
- Suitable as a preservative in aqueous and solvent-based systems.
- Solid powder form for easy handling and formulation.
- High purity for analytical and research applications (typical >99.8%).
- Molecular formula C7H5NOS and molecular weight 151.19 g/mol.
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Medchemexpress LLC 2-Methoxyphenylboronic acid | 5720-06-9 | 151.96 | 100 G
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2-Methoxyphenylboronic acid is a biochemical reagent used in life science research. It functions as a biological material or organic compound.
- Can be used as a biological material or organic compound
- Suitable for life science related research
- Appears as a solid
- Color is white to off-white
- Stores at -20°C for 3 years or 4°C for 2 years (powder)
- Stores at -80°C for 6 months or -20°C for 1 month (in solvent)
- Highly soluble in DMSO (100 mg/mL)
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Medchemexpress LLC Activin Receptor Type IIB Antibody (YA2345) | 10 UL
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Activin Receptor Type IIB (ACVR2B) is a transmembrane serine/threonine kinase that forms an activin receptor complex with type I receptors. It functions as the primary receptor for activin-A, activin-B, and inhibin-A, regulating diverse processes including neuronal differentiation/survival, hair follicle cycling, pituitary FSH production, wound healing, extracellular matrix formation, immunosuppression and carcinogenesis. Upon activation, ACVR2B phosphorylates type I receptors to initiate SMAD2/SMAD3-SMAD4-mediated transcriptional regulation.
- Derived from rabbit host
- Reacts with human, mouse, and rat samples
- Non-conjugated
- SwissProt ID: Q13705
- Research field: Signal Transduction
- Liquid appearance
- Application: WB (1:500-1:1000 dilution)
- Storage at -20°C for 1 year; avoid repeated freeze/thaw cycles
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