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Filtered Search Results
Medchemexpress LLC Alisol F | 155521-45-2 | 488.70 | 1 ML
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Alisol F is a triterpene isolated from *Alisma orientale* that possesses immunosuppressive and anti-virus functions. It exhibits inhibitory activity against hepatitis B virus (HBV) surface antigen (HBsAg) secretion in the HepG2.2.15 cell line with an IC50 of 0.6 μM.
- Exhibits an EC50 of 15.1 μM in the transactivation of FXR in HepG2 cells.
- Shows an IC50 of 0.6 μM for antiviral activity against Hepatitis B virus in human HepG2.2.15 cells.
- Isolated from plants, Alismataceae, *Alisma orientale* (Samuel.) Juz.
- Classified as a triterpene.
- Appears as a white to off-white solid.
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Medchemexpress LLC Methacrylic anhydride | 760-93-0 | MFCD00008586 | 98.8% | 154.17 g·mol⁻¹ | C8H10O3 | 100 MG
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Methacrylic anhydride is a reactive methacrylate derivative used to introduce methacrylate functionality onto polymers, biomolecules, and surfaces. It functions as an acylating reagent in polymer synthesis and surface modification, and is commonly used in free-radical polymerization and biochemical reagent preparation. Handle and store according to safety data recommendations.
- Reactive methacrylate monomer for acylation and methacrylation of polymers and biomolecules.
- Enables free-radical polymerization to introduce polymerizable groups.
- High purity suitable for research and synthesis applications.
- Available as neat material and as solution formats for ease of use.
- Stable under recommended storage conditions; follow SDS for handling.
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eMolecules PRETOMANID 0.1G
5000188108 PRETOMANID 0.1G
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eMolecules PYAOP 100G
5000189029 PYAOP 100G
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Medchemexpress LLC PA-915 (PAC1R antagonist 1) | 2305204-24-2 | 99.2% | 372.81 | 1 ML
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PA-915 (PAC1R antagonist 1), also known as compound 3d, is a potent and orally active antagonist of the PAC1 receptor. It can inhibit pituitary adenylate cyclase-activating polypeptide (PACAP)- and nerve injury-induced allodynia.
- Potent and orally active antagonist
- Inhibits pituitary adenylate cyclase-activating polypeptide (PACAP)
- Inhibits nerve injury-induced allodynia
- For research use only
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Medchemexpress LLC Palladium (II) acetate | 3375-31-3 | 224.51 | 10 G
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Palladium (II) acetate is a catalyst that catalyzes aromatic substitution reactions. It is a yellow to brown solid, intended for research use only.
- Catalyst for aromatic substitution reactions
- For research use only
- Shipped at room temperature in the continental US
- Store at 4°C, protected from light, and under nitrogen
- In solvent, store at -80°C for 6 months or -20°C for 1 month (protected from light, stored under nitrogen)
- Solubility of 100 mg/mL in DMSO (445.41 mM)
- Recommended use of freshly opened DMSO due to hygroscopic properties
- Appearance: Yellow to brown solid
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Apexbio Technology LLC Cysteamine HCl 156-57-0 10mM (in 1mL DMSO)
Cysteamine HCl (156-57-0) is a small-molecule modulator designed to facilitate cystine export from lysosomes by lowering intracellular cystine levels Cysteamine HCl exerts its biological activity primarily through cleaving cystine disulfide bonds and forming mixed disulfides enabling cystine transport out of lysosomes In in vitro assays Cysteamine HCl demonstrates antioxidant activity with reported IC50 values typically ranging between 30 80 M depending on cell type and assay conditions Based on these pharmacological properties Cysteamine HCl holds research potential in studies of cystinosis lysosomal storage disorders oxidative stress-related models and cystine metabolic pathway analysis
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Apexbio Technology LLC Ivacaftor (VX-770)(Synonyms: Kalydeco, VX-770, Ivacaftor, CFTR Potentiator VX-770, Ivacaftor VX-770), 25mg, CAS: 873054-44-5.
Ivacaftor (VX-770 CAS 873054-44-5) is an orally bioavailable small molecule potentiator targeting the cystic fibrosis transmembrane conductance regulator (CFTR) Ivacaftor enhances CFTR-mediated chloride ion transport especially in cells expressing G551D- or F508del-CFTR mutations In vitro studies demonstrated that Ivacaftor in combination with forskolin significantly increased CFTR-dependent chloride secretion (EC50 100 nM in G551D- 25 nM in F508del-expressing cells) Similarly Ivacaftor reduced ENaC-mediated sodium reabsorption and increased airway surface liquid volume in human cystic fibrosis bronchial epithelial cells Ivacaftor is utilized in research to investigate CFTR function restoration and associated ion transport processes
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Medchemexpress LLC O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate | 94790-37-1 | MFCD00075445 | >=98.0% | 379.24 g·mol⁻¹ | C11H16F6N5OP | 1kg
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HBTU is a coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis[1]
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Medchemexpress LLC 1,1'-(9,9-dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | 161265-03-8 | MFCD00233866 | 99.9% | 578.62 g/mol | C39H32OP2 | 25g
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Xantphos (9 9-Dimethyl-4 5-bis(diphenylphosphino)xanthene) is a bisphosphine ligand Xantphos coordinates to metals in either cis or trans chelation mode Xantphos acts as a key ligand in palladium or platinum catalyzed reactions Xantphos can be used in the construction of heterocyclic compounds in organic synthesis[1][2][3]
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Medchemexpress LLC (E)-Fenpyroximate | 134098-61-6 | MFCD00274596 | 99.8% | 1 ML
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(E)-Fenpyroximate is a potent acaricide that functions as a mitochondrial NADH:ubiquinone reductase inhibitor. This compound is widely used as an acaricide, miticide, and insecticide, and is registered for various plant commodities. It is also approved in the EU as an active substance and is currently being investigated for malaria control.
- Potent acaricide
- Functions as a mitochondrial NADH:ubiquinone reductase inhibitor
- Used as a miticide and insecticide
- Registered for use on various plant commodities
- Approved in the EU as an active substance
- Investigated for malaria control
- Appearance as a white to off-white solid
- Molecular formula C24H27N3O4
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Medchemexpress LLC hsa-miR-21-5p mimic 20nmol | 20nmol
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hsa-miR-21-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
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eMolecules 98-08-8 | Benzotrifluoride | Oakwood Chemical | MFCD00000372 | 146.112 | C7H5F3 | 99.000 | FC(F)(F)c1ccccc1 | 500g | 537665256
Benzotrifluoride | Oakwood Chemical | 98-08-8 | MFCD00000372 | 146.112 | C7H5F3 | 99.000 | FC(F)(F)c1ccccc1 | 500g | 537665256
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Medchemexpress LLC E-64 (proteinase inhibitor E 64) | 66701-25-5 | C15H27N5O5 | 1 ML
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E-64 is a potent irreversible inhibitor against general cysteine proteases, with an IC50 of 9 nM for papain. It acts as a cathepsin B-specific inhibitor and its binding modes have been studied at an atomic level with various proteases including papain, actinidin, cathepsin L, and cathepsin K. This compound is widely utilized as a potent and irreversible covalent-type inhibitor for a range of cysteine proteases.
- Potent irreversible inhibitor against general cysteine proteases
- IC50 of 9 nM for papain
- Cathepsin B-specific inhibitor
- Inhibits various cysteine proteases including papain, ficin, actinidin, cathepsin B, and L
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Aobchem 2-Bromo-7-isopropoxynaphthalene | 97% | CAS 2969334-22-1 | C13H13BrO | 10g
2-Bromo-7-isopropoxynaphthalene | 97% | CAS 2969334-22-1 | C13H13BrO | 10g
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