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Filtered Search Results
Ambeed AMBEED
5000870288 2-FLUOROBENZYLHYDRAZINE HY 5GR
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Ambeed AMBEED
5000882793 256-TRIAMINOPYRIMIDIN-43 25G
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Medchemexpress LLC Vernakalant hydrochloride | 748810-28-8 | MFCD09833303 | 99.3% | C20H32ClNO4 | 10MG
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Vernakalant hydrochloride is a research chemical that acts as a mixed voltage- and frequency-dependent sodium channel blocker and an atria-preferred potassium channel blocker, used to investigate atrial electrophysiology and arrhythmia mechanisms. It is supplied in solid and DMSO solution formats and is characterized by defined molecular properties for in vitro studies.
- High purity (99.33%).
- Available as solid and 10 mM DMSO solution.
- Suitable for in vitro electrophysiology and pharmacology studies.
- Molecular formula C20H32ClNO4; molecular weight 385.93 g·mol⁻¹.
- For research use only; not for human or veterinary use.
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Aobchem (3-(Cyclohexylmethoxy)phenyl)(methyl)sulfane | 95% | C14H20OS | 1g
(3-(Cyclohexylmethoxy)phenyl)(methyl)sulfane | 95% | C14H20OS | 1g
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Aobchem (3-(Cyclohexylmethoxy)phenyl)(methyl)sulfane | 95% | C14H20OS | 250mg
(3-(Cyclohexylmethoxy)phenyl)(methyl)sulfane | 95% | C14H20OS | 250mg
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Ambeed AMBEED
5000883630 AI 3-09536 500G
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Medchemexpress LLC Guretolimod hydrochloride | 00-00-0 | 98.7% | C24H35ClF3N5O4 | 10MG
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Guretolimod hydrochloride is a Toll-like receptor 7 (TLR7) agonist supplied as the hydrochloride salt for research use. It is intended for laboratory studies probing TLR7-mediated immune activation and innate immune signaling; not for human or clinical use.
- High chemical purity (98.67%).
- Molecular formula C24H35ClF3N5O4 with molecular weight 550.01 Da.
- Selective TLR7 agonist activity for immune-response research.
- Provided as a hydrochloride salt to aid solubility in common solvents.
- Available in small milligram pack sizes suitable for screening.
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Medchemexpress LLC Luvixasertib hydrochloride | 1610677-37-6 | 99.6% | 535.04 g/mol | C28H31ClN6O3 | 50 MG
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Luvixasertib hydrochloride is a selective, orally bioavailable small-molecule inhibitor of TTK/Mps1 used for preclinical research. It inhibits TTK/Mps1 with an in vitro IC50 of 1.7 nM and has demonstrated anticancer activity in cell-based studies.
- Selective TTK/Mps1 inhibition with IC50 of 1.7 nM.
- Orally bioavailable scaffold suitable for in vivo studies.
- Hydrochloride salt form improves solubility and handling.
- High reported purity (≈99.6%) for research reproducibility.
- Supplied in small research quantities for assay development and compound characterization.
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Medchemexpress LLC Gsk 3008348 hydrochloride | 1629249-40-6 | 99.9% | 25 MG
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GSK 3008348 hydrochloride is a small molecule antagonist of integrin αvβ6. It inhibits TGF-β activation, alleviating the fibrotic process, and prevents foot-and-mouth disease virus entry by targeting the αvβ6 integrin receptor. This compound is used in research for pulmonary fibrosis and various types of cancer.
- Antagonizes integrin αvβ6
- Inhibits TGF-β activation
- Alleviates the fibrotic process
- Prevents foot-and-mouth disease virus binding to the αvβ6 integrin receptor
- Supports research on pulmonary fibrosis
- Supports research on various types of cancer
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Medchemexpress LLC Parsaclisib hydrochloride | 1995889-48-9 | 99.3% | 469.34 | 25 MG
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Parsaclisib hydrochloride is a potent, selective, and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. It exhibits approximately 20000-fold selectivity over other PI3K class I isoforms. It is used for the research of relapsed or refractory B-cell malignancies.
- Potent, selective, and orally active PI3Kδ inhibitor
- Exhibits approximately 20000-fold selectivity over other PI3K class I isoforms
- Inhibits proliferation of MCL and DLBCL cell lines
- Inhibits anti-IgM-induced pAKT (Ser473) in Ramos Burkitt's lymphoma cell line
- Inhibits proliferation of human, dog, rat, and mouse primary B cells
- Inhibits tumor growth in BALB/c mice bearing A20 murine lymphoma cells
- Slows Pfeiffer xenograft tumor growth in a dose-dependent manner
- Reduces percentage of Tregs (CD4+CD25+FOXP3+) in tumors and spleens
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Cayman Chemical 8piperazin1ylIsoquinoline hy
A synthetic intermediate useful for pharmaceutical synthesis.
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Medchemexpress LLC Epetraborole hydrochloride | 1234563-16-6 | 99.6% | 273.52 g·mol⁻1 | C11H17BClNO4 | 50MG
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Epetraborole hydrochloride is a boron-containing leucyl-tRNA synthetase inhibitor supplied for laboratory research into antibacterial mechanisms. The material is provided in small pack sizes for experimental use and is accompanied by batch COA and safety documentation for handling and quality verification.
- Boron-containing leucyl-tRNA synthetase inhibitor used in antibacterial research.
- Chemical name: Epetraborole hydrochloride.
- CAS number: 1234563-16-6.
- Molecular formula: C11H17BClNO4; molecular weight: 273.52 g·mol⁻1.
- Purity (LCMS): 99.6%.
- Reported bioactivity: leucyl-tRNA synthetase IC50 ≈ 0.31 μM.
- Supplied in small research pack sizes, with batch COA and SDS available.
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Medchemexpress LLC Pardoprunox hydrochloride | 269718-83-4 | 99.5% | 269.73 | 50 MG
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Pardoprunox (SLV-308) hydrochloride is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively. For research use only. We do not sell to patients.
- Pardoprunox hydrochloride acts as a potent but partial D2 receptor agonist (pEC50= 8.0 and pA2=8.4) with 50% efficacy on forskolin stimulated cAMP accumulation.
- At human recombinant dopamine D3 receptors, Pardoprunox hydrochloride acts as a partial agonist (intrinsic activity of 67%; pEC50=9.2) and antagonized dopamine induction of [(35)S]GTPgammaS binding (pA2=9.0).
- Pardoprunox hydrochloride acts as a full 5-HT1A receptor agonist on forskolin induced cAMP accumulation at cloned human 5-HT1A receptors but with low potency (pEC50=6.3).
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Medchemexpress LLC Tracazolate hydrochloride | 1135210-68-2 | 99.24% | 50 MG
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Tracazolate hydrochloride is a potent GABAA receptor modulator, demonstrating selectivity for β3 and potentiating α1β1γ2s (EC50=13.2 μM) and α1β3γ2 (EC50=1.5 μM). Its potency is influenced by the nature of the third subunit within the receptor complex. This compound also exhibits anxiolytic and anticonvulsant properties.
- Potent GABAA receptor modulator
- Selectivity for β3
- Potentiates α1β1γ2s and α1β3γ2
- Possesses anxiolytic and anticonvulsant activity
- Interacts with GABAA receptors, adenosine receptors, and phosphodiesterases
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Medchemexpress LLC Mavorixafor hydrochloride | 880549-30-4 | 99.6% | C21H28ClN5 | 100 MG
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Mavorixafor hydrochloride (AMD-070) is a potent, selective, and orally available CXCR4 antagonist with an IC50 value of 13 nM against CXCR4 125I-SDF binding. It also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with IC50 values of 1 nM and 9 nM, respectively. This compound can be used for the study of WHIM syndrome.
- Potent and selective CXCR4 antagonist.
- Orally available.
- Inhibits replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs.
- Used for the study of WHIM syndrome.
- Shows no effect on other chemokine receptors (CCR1, CCR2b, CCR4, CCR5, CXCR1, and CXCR2).
- Significantly suppresses anchorage-dependent growth of B88-SDF-1 cells.
- Impairs motility and inhibits migration and Matrigel invasion of B88-SDF-1 cells.
- Inhibits lung metastasis of B88 SDF 1 cells in nude mice.
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