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Filtered Search Results
Medchemexpress LLC AZ10606120 dihydrochloride | 607378-18-7 | 99.9% | 495.48 | 5 MG
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AZ10606120 dihydrochloride | 607378-18-7 | 99.9% | 495.48 | 5 MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429441 3-ACETAMIDOPHTHALIC 10G
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Apexbio Technology LLC Butenafine HCl 101827-46-7 10mM (in 1mL DMSO)
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Butenafine HCl (CAS 101827-46-7) is a small-molecule inhibitor targeting squalene epoxidase It is designed to inhibit this enzyme thereby disrupting fungal sterol biosynthesis Butenafine HCl exerts its biological activity primarily through inhibition of squalene epoxidase leading to impaired ergosterol synthesis and accumulation of squalene which disrupts fungal cell membrane integrity and results in cell death In biochemical studies Butenafine HCl demonstrates inhibitory activity with reported IC50 values ranging from approximately 0 03 M to 0 1 M depending on fungal species and experimental conditions Based on these pharmacological properties Butenafine HCl holds research potential in biomedical antifungal studies including investigations into fungal physiology antifungal efficacy and drug resistance mechanisms
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Apexbio Technology LLC Valnemulin HCl 133868-46-9 10mM (in 1mL DMSO)
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Valnemulin HCl (CAS 133868-46-9) is a small-molecule inhibitor targeting bacterial protein synthesis It is designed to inhibit the peptidyl transferase activity of the bacterial 50S ribosomal subunit thereby disrupting peptide bond formation and bacterial growth Valnemulin HCl exerts its biological activity primarily through specific binding to the peptidyl transferase region within the 50S ribosomal subunit In experimental animal models valnemulin HCl demonstrates inhibitory effects on Mycoplasma bovis proliferation in calf lung tissues with reported IC50 values against various bacterial isolates ranging from approximately 0 03 to 0 5 g/mL depending on the bacterial strain Based on these pharmacological properties valnemulin HCl holds research potential in the management of bacterial infections including applications in epizootic rabbit enteropathy and respiratory diseases in livestock
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Research Products International Corp 4NitroPhos bisCyclohexylam 25G
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Free PNP: <250ppm
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Apexbio Technology LLC HyperScript™ IV First-Strand cDNA Synthesis SuperMix 50rxn
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HyperScript IV First-Strand cDNA Synthesis SuperMix is a reagent kit incorporating an engineered reverse transcriptase derived from M-MLV Reverse Transcriptase It is designed to efficiently catalyze first-strand cDNA synthesis from RNA templates thereby enabling reverse transcription required for downstream molecular analyses HyperScript IV First-Strand cDNA Synthesis SuperMix exhibits high activity enhanced inhibitor resistance extended elongation capability improved reaction kinetics and reduced RNase H activity supporting efficient full-length cDNA synthesis Synthesized cDNA is compatible with downstream applications such as PCR amplification and quantitative PCR (qPCR)
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429358 1-ACETYLNAPHTHALENE 250G
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Medchemexpress LLC Benzenepropanamide, a-[[(1,2-dihydro-2-oxo-6-quinolinyl)sulfonyl)amino]-N-(2-furanylmethyl)-N-(2-thienylmethyl)- | 1681056-62-1 | 98.0% | 547.65 | 25 MG
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PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor with an IC50 of 68 μM and a close structural analog of OSMI-1. In vitro studies show that PG34, at concentrations up to 50 μM for 24 hours, does not detectably inhibit OGT in CHO cells, nor does it affect apoptotic signaling. A moderate effect on cell viability was observed only at the highest concentration of 50 μM.
- Weak O-GlcNAc transferase (OGT) inhibitor
- IC50 of 68 μM
- Structural analog of OSMI-1
- Does not inhibit OGT in CHO cells (0.5-50 μM)
- No effect on apoptotic signaling
- Moderate effect on cell viability at 50 μM
- No reduction in global O-GlcNAcylation (10, 25, 50 μM)
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Apexbio Technology LLC Tetrahydro-β-carboline 16502-01-5 1g
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Tetrahydro- -carboline (CAS 16502-01-5) is a -carboline alkaloid derivative characterized by a tetrahydroindole fused to a pyridine ring This compound modulates neurotransmitter dynamics in the central nervous system by interacting with specific receptors and enzymes thereby influencing neurotransmitter release and metabolism Tetrahydro- -carboline has been utilized in studies on drug dependence neuroprotection and cognitive function within neuropharmacology Its molecular framework supports applications in the development of lead compounds and the investigation of neurobiological pathways involved in central nervous system disorders
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Medchemexpress LLC 2-phenylmelatonin | 151889-03-1 | MFCD00673896 | 99.2% | 308.37 g/mol | C19H20N2O2 | 10 MG
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UCM 608 (2-Phenylmelatonin) is a high-affinity melatonin (MT) receptor agonist supplied as a purified solid for laboratory research. It binds MT1 and MT2 receptors with reported pKi values of 10.7 and 10.4, respectively, and is used in pharmacology and receptor-binding studies. Handle and store according to safety data and laboratory protocols.
- High affinity for MT1 and MT2 receptors.
- Reported pKi values: MT1 10.7, MT2 10.4.
- Molecular formula C19H20N2O2.
- Molecular weight 308.37 g/mol.
- Purity approximately 99.18% (reported).
- Solid, off-white to yellow appearance.
- Store powder at -20°C or 4°C per stability guidance.
- Intended for research use only.
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eMolecules HEXADECYLTRIMETHOXYSILANE 25G
5000160171 HEXADECYLTRIMETHOXYSILANE 25G
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Medchemexpress LLC Bis(dibenzylideneacetone)palladium | 32005-36-0 | 575.00 | 500 MG
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Bis(dibenzylideneacetone)palladium is a biochemical reagent used as a biological material or organic compound for life science related research. It serves as a reagent for preparing allylic substituted cyclopentadienes, and acts as a homogeneous catalyst for the alkylation of allyl acetates by various nucleophiles. It is also utilized in Suzuki reactions.
- Utilized in hydrogenation
- Utilized in isomerization
- Utilized in carbonylation
- Utilized in oxidation
- Utilized in C-C bond formation reactions
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Medchemexpress LLC Pardoprunox hydrochloride | 269718-83-4 | 99.5% | 269.73 | 25 MG
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Pardoprunox hydrochloride (SLV-308) is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist. It demonstrates potent partial agonism at D2 receptors and partial agonism at D3 receptors, while also acting as a full agonist for 5-HT1A receptors.
- Partial dopamine D2 and D3 receptor agonist
- Serotonin 5-HT1A receptor agonist
- Potent partial D2 receptor agonist with 50% efficacy on forskolin stimulated cAMP accumulation
- Partial agonist at human recombinant dopamine D3 receptors, inducing [(35)S]GTPgammaS binding
- Full 5-HT1A receptor agonist on forskolin induced cAMP accumulation
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Medchemexpress LLC Arc186 sodium | 1 MG
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ARC186 sodium is an unconjugated 40KDa PEG aptamer with a sequence identical to ARC1905 sodium. This highly potent complement inhibitor functions by blocking the convertase-catalyzed activation of C5.
- Purity: 94.13%
- Appearance: Solid
- Color: White to off-white
- Active in immunology and inflammation pathways
- Inhibits the complement system
- Relevant for inflammation or immune system disease research
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000376961 ILORASERTIB HYDROCH 10MM 1ML
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