Carboxylic acid esters

Organic compounds that are directly derived from carboxylic acid, and contain an ester functional group substitution; ester groups contain an oxygen atom that is bonded to two carbon atoms or organic groups via single bonds.

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676 – 690 of 1,398 results

676

Medchemexpress LLC Neratinib maleate | 915942-22-2 | 99.7% | 673.11 | 25 MG

Neratinib maleate is an orally available, irreversible, and highly selective inhibitor of HER2 and EGFR, intended for research use only. It inhibits the proliferation of cell lines expressing high levels of HER-2 and demonstrates anticancer activities in vivo by reducing tumor growth in a dose-dependent manner in various xenografts.

Orally available, irreversible, highly selective HER2 and EGFR inhibitor.
Inhibits proliferation of cell lines with high HER-2 levels.
Arrests cell cycle at G1-S phase.
Inhibits MAPK and Akt phosphorylation.
Down-regulates cyclin D1 levels and induces p27.
Shows anticancer activities against HER-2 or EGFR expressing cancer cells in vivo.

Pricing & Availability

677

Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.8% | 391.42 | 25 MG

Omigapil maleate (CGP3466B) is an orally active GAPDH nitrosylation inhibitor that abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. It has potential for Alzheimer's disease research and is also an apoptosis inhibitor. Additionally, it can be used for congenital muscular dystrophy (CMD) research.

Orally active GAPDH nitrosylation inhibitor.
Abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice.
Potential for Alzheimer's disease research.
Apoptosis inhibitor.
Can be used for congenital muscular dystrophy (CMD) research.
Click chemistry reagent with an alkyne group for CuAAc reactions.

Pricing & Availability

678

TARGETMOL CHEMICALS INC DIZOCILPINE MALEATE 50MG

Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membranes. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. purity: 99%

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679

Medchemexpress LLC Quipazine maleate 500mg | 500MG

Quipazine maleate 500mg | 500MG

Pricing & Availability

680

Medchemexpress LLC BRL-44408 maleate | 681806-46-2 | MFCD02262218 | 99.0% | 331.37 g/mol | C17H21N3O4 | 5 MG

BRL-44408 maleate is a small-molecule α2A-adrenoceptor antagonist used in preclinical pharmacology research. It shows high affinity for α2A receptors (Ki ≈ 8.5 nM) and has demonstrated antidepressant and analgesic activity in animal studies.

Selective α2A-adrenoceptor antagonist with Ki ≈ 8.5 nM.
Demonstrates antidepressant and analgesic activity in preclinical models.
Solid, light brown to brown appearance.
Molecular weight 331.37 g/mol; formula C17H21N3O4.
Purity 99.0% (HPLC).
Soluble in DMSO at 30 mg/mL; may require ultrasonic and warming.
Store sealed, away from moisture at -20 °C; in solution, store at -80 °C for long-term stability.

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681

eMolecules 5089-70-3 | (3-Chloropropyl)triethoxysilane | Ambeed | MFCD00018985 | 240.800 | C9H21ClO3Si | 97.000 | CCO[Si](CCCCl)(OCC)OCC | 25g | 491684614

(3-Chloropropyl)triethoxysilane | Ambeed | 5089-70-3 | MFCD00018985 | 240.800 | C9H21ClO3Si | 97.000 | CCO[Si](CCCCl)(OCC)OCC | 25g | 491684614

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682

eMolecules 922-67-8 | Methyl propiolate | Ambeed | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 25g | 552720844

Methyl propiolate | Ambeed | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 25g | 552720844

Pricing & Availability

683

eMolecules 1150114-53-6 | (5-((tert-Butyldimethylsilyl)oxy)-2-fluorophenyl)boronic acid | Ambeed | MFCD11855846 | 270.180 | C12H20BFO3Si | 98.000 | CC(C)(C)[Si](C)(C)Oc1ccc(F)c(c1)B(O)O | 100mg | 717401769

(5-((tert-Butyldimethylsilyl)oxy)-2-fluorophenyl)boronic acid | Ambeed | 1150114-53-6 | MFCD11855846 | 270.180 | C12H20BFO3Si | 98.000 | CC(C)(C)[Si](C)(C)Oc1ccc(F)c(c1)B(O)O | 100mg | 717401769

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684

Medchemexpress LLC IMMH-010 maleate | 2541982-47-0 | 99.8% | 756.04 | 1 MG

IMMH-010 maleate is a prodrug that serves as a novel PD-L1 inhibitor, exhibiting potential antitumor activity for the treatment of neurological disorders and advanced malignant solid tumors. It is rapidly converted to its active form, YPD-29B, following oral administration. IMMH-010 maleate is poised for advancing research in the field of PD-L1 inhibitors and related therapeutic applications.

Novel PD-L1 inhibitor
Exhibits potential antitumor activity for neurological disorders and advanced malignant solid tumors
Prodrug that rapidly converts to its active form, YPD-29B, following oral administration
Poised for advancing research in the field of PD-L1 inhibitors and related therapeutic applications

Pricing & Availability

685

Medchemexpress LLC U-99194 maleate | 234757-41-6 | 99.2% | 10 MG

U-99194 maleate is a selective, potent dopamine D3 receptor antagonist with a Ki of 160 nM. It inhibits the activation of the D3 receptor mediated by endogenously released dopamine or exogenous D3 agonists. This compound can be used for the study of dopamine D3 receptor-mediated motor disorders, particularly kinetic tremors.

Selective, potent dopamine D3 receptor antagonist
Inhibits activation of D3 receptor
Abrogates IPSC-suppressive effect of D3 agonist PD 128907 in rat hippocampal slices
Significantly suppresses nicotine-induced tremor in mice

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686

Medchemexpress LLC Lisuride maleate | 19875-60-6 | 454.52 | 1 ML

Lisuride maleate is a potent dopamine agonist that directly acts on dopaminergic receptors. This ergot derivative can release premenstrual mastalgia without significant side effects. Research indicates its in vivo potency, demonstrating effectiveness in antagonizing motor depression and hypothermia. It has also been involved in clinical trials for conditions such as Parkinson's Disease, Restless Legs Syndrome, and Cocaine-Related Disorders.

Potent dopamine agonist
Releases premenstrual mastalgia
Antagonizes motor depression and hypothermia
Used in clinical trials for neurological disorders
Stable under recommended storage conditions
Soluble in various solvents for research applications

Pricing & Availability

687

Medchemexpress LLC Edonerpic maleate | 519187-97-4 | 99.8% | 407.48 | C20H25NO6S | 10 MG

Edonerpic maleate is a research-grade neurotrophic agent reported to inhibit amyloid-β (Aβ) peptides. Supplied as a white to off-white solid and available in small milligram pack sizes or as a DMSO solution, it is intended for laboratory research use only and not for human or clinical applications.

Inhibits amyloid-β peptide activity in reported studies.
Solid form suitable for storage and versatile for in vitro use.
High chemical purity: 99.8% (LCMS).
Molecular weight 407.48 g/mol.
Available as small milligram quantities and a 10 mM DMSO solution.
For research use only; not for human consumption.

Pricing & Availability

688

Medchemexpress LLC Filgotinib maleate | 1802998-75-9 | 99.88% | 541.58 | 25 MG

Filgotinib maleate (GLPG0634 maleate) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. It effectively inhibits the activities of JAK1, JAK2, JAK3, and TYK2 with IC50 values of 10 nM, 28 nM, 810 nM, and 116 nM, respectively. It also inhibits HIV-1 driven gene transcription and reduces the proliferation of HIV-1 infected cells. It can be used in the study of rheumatoid arthritis and inflammatory bowel disease.

Selective, orally available JAK1 inhibitor
Exhibits anti-inflammatory activities
Demonstrates antiviral activities
Inhibits HIV-1 driven gene transcription
Reduces proliferation of HIV-1 infected cells
Potential for use in rheumatoid arthritis research
Potential for use in inflammatory bowel disease research

Pricing & Availability

689

Medchemexpress LLC Vicriviroc maleate | 599179-03-0 | MFCD09833218 | 99.9% | 649.70 | 1 ML

Vicriviroc maleate is a potent, selective, and orally bioavailable CCR5 antagonist. It is CNS penetrated with a Ki of 2.5 nM. This compound effectively inhibits HIV-1 in PBMC cells across various strains.

Potent and selective CCR5 antagonist
Oral bioavailable and CNS penetrated
Inhibits HIV-1 in PBMC cells
Active against multiple HIV-1 strains

Pricing & Availability

690

Medchemexpress LLC 4-PPBP maleate | 201216-39-9 | 99.6% | 409.52 g/mol | C25H31NO4 | 50 MG

4-PPBP maleate is a research-grade sigma-1 (σ1) receptor ligand and agonist used in neuroscience studies. It acts as a non-competitive, selective antagonist of NR1a/2B NMDA receptors and has been used in models of neuroprotection. The compound is supplied as a solid with high reported purity and defined storage recommendations for stability.

Potent sigma-1 receptor ligand and agonist.
Non-competitive, selective NR1a/2B NMDA receptor antagonist.
Used in neuroprotection research models.
High purity (99.6%).
Supplied as a solid for convenient handling.
Stable when stored sealed at 4°C; solvent storage conditions applicable.

Pricing & Availability

Carboxylic acid esters

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Medchemexpress LLC Neratinib maleate | 915942-22-2 | 99.7% | 673.11 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.8% | 391.42 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC DIZOCILPINE MALEATE 50MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Quipazine maleate 500mg | 500MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BRL-44408 maleate | 681806-46-2 | MFCD02262218 | 99.0% | 331.37 g/mol | C17H21N3O4 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC IMMH-010 maleate | 2541982-47-0 | 99.8% | 756.04 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC U-99194 maleate | 234757-41-6 | 99.2% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Lisuride maleate | 19875-60-6 | 454.52 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Edonerpic maleate | 519187-97-4 | 99.8% | 407.48 | C20H25NO6S | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Filgotinib maleate | 1802998-75-9 | 99.88% | 541.58 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Vicriviroc maleate | 599179-03-0 | MFCD09833218 | 99.9% | 649.70 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4-PPBP maleate | 201216-39-9 | 99.6% | 409.52 g/mol | C25H31NO4 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More