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Filtered Search Results
Apexbio Technology LLC Cinepazide maleate 26328-04-1 10mM (in 1mL DMSO)
Cinepazide maleate (CAS 26328-04-1) is the maleate salt of cinepazide classified as a vasodilatory agent It exerts its effects primarily through inhibition of calcium influx in vascular smooth muscle cells leading to vessel relaxation and increased blood flow This mechanism is associated with reduced peripheral resistance and enhanced microcirculation Cinepazide maleate has been utilized in research exploring vascular tone modulation cerebral blood flow and ischemia models providing a tool for investigating mechanisms of vasodilation and circulatory disorders in preclinical settings
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Medchemexpress LLC Indacaterol maleate | 753498-25-8 | MFCD20526769 | 99.8% | 508.56 g/mol | C28H32N2O7 | 5 MG
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Indacaterol maleate is the maleate salt of indacaterol, an ultra-long-acting β2-adrenergic receptor agonist. Supplied as an analytical standard, this solid reference material is intended for research use in assay development, method validation, and quality control testing.
- High purity (99.8%).
- Suitable for assay development and method validation.
- Confirmed identity by LC-MS consistent with structure.
- Stable solid form for accurate weighing and storage.
- Includes CAS 753498-25-8 and molecular weight 508.56 g/mol.
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Medchemexpress LLC Ro 25-6981 Maleate | 1312991-76-6 | 99.3% | 455.54 | 1 ML
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Ro 25-6981 Maleate is a potent, selective, and activity-dependent antagonist of the NMDA receptor containing the NR2B subunit. It demonstrates anticonvulsant and anti-parkinsonian activity, making it a valuable compound for Parkinson's disease research.
- Potent and selective NMDA receptor antagonist
- Specific for NR2B subunit
- Demonstrates anticonvulsant activity
- Demonstrates anti-parkinsonian activity
- Useful for Parkinson's disease research
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eMolecules 91388-25-9 | 1-Bromo-2-(2-methyl-propenyl)-benzene | J & W PharmLab LLC | MFCD29034263 | 211.102 | C10H11Br | 96.000 | CC(C)=Cc1ccccc1Br | 1g | 448727036
1-Bromo-2-(2-methyl-propenyl)-benzene | J & W PharmLab LLC | 91388-25-9 | MFCD29034263 | 211.102 | C10H11Br | 96.000 | CC(C)=Cc1ccccc1Br | 1g | 448727036
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Medchemexpress LLC Filgotinib (maleate) | 1802998-75-9 | 99.88% | 541.58 | 1 ML
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Filgotinib maleate (GLPG0634 maleate) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. It can effectively inhibit the activities of JAK1, JAK2, JAK3, and TYK2. This compound also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. It can be used in the study of rheumatoid arthritis and inflammatory bowel disease.
- Selective, orally available JAK1 inhibitor
- Anti-inflammatory and antiviral activities
- Inhibits activities of JAK1, JAK2, JAK3, and TYK2
- Inhibits HIV-1 driven gene transcription
- Reduces proliferation of HIV-1 infected cells
- Suitable for research in rheumatoid arthritis and inflammatory bowel disease
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Medchemexpress LLC Flupirtine (maleate) | 75507-68-5 | 99.97% | 420.39 | 10 MG
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Flupirtine (maleate) | 75507-68-5 | 99.97% | 420.39 | 10 MG
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Medchemexpress LLC Cediranib maleate | 857036-77-2 | MFCD09954115 | 100.0% | C29H31FN4O7 | 10MG
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Cediranib maleate is the maleate salt of cediranib (AZD-2171), a potent orally available vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor supplied for research use. It is provided as a high-purity solid and is also available in ready-to-use DMSO stock solutions for biochemical and cell-based assays.
- High purity 99.95%.
- Potent VEGFR inhibitor with low-nanomolar activity against Flt1, KDR, Flt4, PDGFRα/β, and c-Kit.
- Suitable for in vitro and in vivo research applications.
- Supplied as a solid and as 10 mM DMSO solutions.
- Molecular formula C29H31FN4O7; molecular weight 566.58 Da.
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eMolecules 92511-12-1 | tert-Butyl(4-iodobutoxy)diMethylsilane | Ambeed | MFCD01863695 | 314.282 | C10H23IOSi | 95.000 | CC(C)(C)[Si](C)(C)OCCCCI | 250mg | 600839556
tert-Butyl(4-iodobutoxy)diMethylsilane | Ambeed | 92511-12-1 | MFCD01863695 | 314.282 | C10H23IOSi | 95.000 | CC(C)(C)[Si](C)(C)OCCCCI | 250mg | 600839556
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Medchemexpress LLC Enalapril (maleate) | 76095-16-4 | 99.99% | 5 G
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Enalapril (MK-421) maleate is an angiotensin-converting enzyme (ACE) inhibitor and the active metabolite of enalapril. This prodrug is rapidly metabolized in the liver to enalaprilat after oral administration. It is a potent, competitive inhibitor of ACE, an enzyme crucial for converting angiotensin I to angiotensin II, which regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).
- Treats essential or renovascular hypertension
- Treats symptomatic congestive heart failure
- Functions as a potent, competitive ACE inhibitor
- Metabolized to enalaprilat in the liver
- For research use only
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Medchemexpress LLC Filgotinib (maleate) | 1802998-75-9 | 50 MG
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Filgotinib maleate (GLPG0634 maleate) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. It inhibits JAK1, JAK2, JAK3, and TYK2 with varying IC50 values. This compound also demonstrates the ability to inhibit HIV-1 driven gene transcription and reduce the proliferation of HIV-1 infected cells, making it suitable for studies related to rheumatoid arthritis and inflammatory bowel disease.
- Selectively inhibits JAK1
- Possesses anti-inflammatory and antiviral properties
- Inhibits HIV-1 driven gene transcription
- Reduces proliferation of HIV-1 infected cells
- Applicable for rheumatoid arthritis research
- Applicable for inflammatory bowel disease research
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Medchemexpress LLC Cediranib maleate | 857036-77-2 | 99.95% | 100 MG
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Cediranib maleate is a highly potent, orally available VEGFR inhibitor. It inhibits VEGF-stimulated proliferation and KDR phosphorylation, reducing vessel area, length, and branching. It ablates experimental angiogenesis and inhibits endochondral ossification and corpora luteal development. It also inhibits the growth of established human tumor xenografts in athymic mice, showing a reduction in microvessel density within tumors.
- Highly potent, orally available VEGFR inhibitor
- Inhibits VEGF-stimulated proliferation and KDR phosphorylation
- Reduces vessel area, length, and branching
- Ablates experimental angiogenesis
- Inhibits endochondral ossification and corpora luteal development
- Inhibits growth of established human tumor xenografts
- Reduces microvessel density within tumors
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eMolecules 2828446-92-8 | Ambeed | 2-(((tert-Butyldimethylsilyl)oxy)methyl)-5-(4455-tetramethyl-132-dioxaborolan-2-yl)thiazole | 100mg | 491657158 | A307802 | MFCD19689425 | 355.38 | C16H30BNO3SSi
Ambeed | 1-Methyl-2-oxo-12-dihydropyridine-4-carbonitrile | 100mg | 518523937 | A126143 | 70411-83-5 | MFCD27923636 | 134.138 | C7H6N2O
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eMolecules 77758-51-1 | Methyl 5-hexynoate | Combi-Blocks | MFCD00671366 | 126.155 | C7H10O2 | 95.000 | COC(=O)CCCC#C | 1g | 415500572
Methyl 5-hexynoate | Combi-Blocks | 77758-51-1 | MFCD00671366 | 126.155 | C7H10O2 | 95.000 | COC(=O)CCCC#C | 1g | 415500572
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eMolecules 7283-69-4 | Diisobutyl fumarate | Combi-Blocks, Inc. | MFCD00152430 | 228.288 | C12H20O4 | 98.000 | CC(C)COC(=O)\C=C\C(=O)OCC(C)C | 25g | 603134297
Diisobutyl fumarate | Combi-Blocks, Inc. | 7283-69-4 | MFCD00152430 | 228.288 | C12H20O4 | 98.000 | CC(C)COC(=O)\C=C\C(=O)OCC(C)C | 25g | 603134297
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Apexbio Technology LLC NB-598 Maleate 155294-62-5 50mg
NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
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