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Filtered Search Results
AdipoGen Dihydrofluorescein diacetate
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Chemical. CAS 35340-49-9. Formula C24H18O7. MW 418.4. Synthetic. Dihydrofluorescein diacetate is a fluorescent probe for detecting intracellular oxidants. It is hydrolyzed by cellular esterases to dihydrofluorescein and is then oxidized to fluorescein primarily by H2O2. Dihydrofluorescein diacetate might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. Cell-loading studies indicate that dihydrofluorescein achieves higher intracellular concentrations than the other redox sensors such as Dihydrorhodamine 123 Ex/Em 490/514nm.
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Cayman Chemical FluoresceIn dIacetate 10g
A cell-permeable fluorogenic cell viability probe; cleaved by intracellular esterases to produce fluorescein which displays excitation/emission maxima of 490/520 nm, respectively
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Medchemexpress LLC Cefcapene pivoxil hydrochloride hydrate | 147816-24-8 | MFCD01682041 | 99.4% | 622.11 g/mol | C23H32ClN5O9S2 | 100 MG
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Cefcapene pivoxil hydrochloride hydrate is a cephalosporin-class antibiotic research compound supplied as a hydrochloride hydrate salt. It is used in in vitro and preclinical studies to evaluate antibacterial activity and related pharmacology, and is distributed with supporting quality and safety documentation.
- High reported purity suitable for analytical and research use.
- Provided with data sheet, certificate of analysis, and safety data sheet for traceability and handling.
- Suitable for in vitro antibacterial and pharmacological research applications.
- Available in multiple small pack sizes for laboratory studies.
- Storage and handling information supplied to maintain stability and safety.
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Cayman Chemical FluoresceIn dIacetate 25g
A cell-permeable fluorogenic cell viability probe; cleaved by intracellular esterases to produce fluorescein which displays excitation/emission maxima of 490/520 nm, respectively
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AdipoGen Fluoresdiacetate 5maleimide
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Chemical. CAS 150322-01-3. Formula C28H17NO9. MW 511.4. Synthetic. Fluorescent marker used extensively in microscopy studies. Can be used in photoluminometric immunoassays for the formation of conjugates with immunoreactants by fluorescent energy transfer.
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eMolecules 3-Propoxy-2,4,6-trifluorophenylboronic acid | 871125-70-1 | 1G | Purity: 95%
Combi-Blocks | 3-Propoxy-2,4,6-trifluorophenylboronic acid | 1G | 871125-70-1 | MFCD07784389
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Medchemexpress LLC PTP1B-IN-4 | 765317-72-4 | 99.6% | 741.45 g/mol | C26H19Br2N3O7S3 | 10 MG
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PTP1B-IN-4 is a small-molecule, non-competitive allosteric inhibitor of protein tyrosine phosphatase 1B (PTP1B) with a reported IC50 of approximately 8 μM. It is intended for biochemical and cellular research into PTP1B-related signaling pathways, including studies of metabolism, obesity, and diabetes. The compound is supplied as a powder or as a DMSO solution for research use.
- Non-competitive allosteric inhibitor of PTP1B (IC50 ≈ 8 μM).
- High purity (99.55%).
- Available as powder and as 10 mM solution in DMSO.
- Pack sizes suitable for small-scale research (1-100 mg).
- Recommended storage: powder at -20°C; in solvent at -80°C (long term).
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Medchemexpress LLC HY-111139 10mg Medchemexpress, MS417 CAS:916489-36-6 Purity:>98%
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Medchemexpress, HY-111139 10mg MS417 CAS:916489-36-6 MS417 is a BET-specific BRD4 inhibitor, binds to BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively, with weak selectivity at CBP BRD (IC50, 32.7 μM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Chemscene ChemScene | Methyl benzimidazole-5-carboxylate | 25G | CS-W022885 | 0.98 | 26663-77-4| MFCD03407310 | 176.18
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ChemScene | Methyl benzimidazole-5-carboxylate | 25G | CS-W022885 | 0.98 | 26663-77-4| MFCD03407310 | 176.18
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Apexbio Technology LLC NB-598 Maleate 155294-62-5 200mg
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NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
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Cayman Chemical Thioperamide maleate
A selective histamine H3 receptor antagonist that crosses the blood-brain barrier; binds to rat cerebral cortical cells in vitro with a pKi value of 8.4
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Apexbio Technology LLC Flupirtine maleate 75507-68-5 1g
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Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
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Medchemexpress LLC Avitinib maleate | 1557268-88-8 | MFCD29089376 | 99.9% | 603.60 | C30H30FN7O6 | 10 MG
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Avitinib maleate is a third-generation, irreversible, orally active EGFR inhibitor supplied as the maleate salt for research use. It exhibits potent activity against EGFR L858R and T790M mutations, with reported BTK inhibitory activity, and is provided with analytical data confirming high purity. Typical formats include small solid quantities and DMSO solutions for laboratory studies.
- Third-generation, irreversible EGFR inhibitor suitable for targeted research.
- Potent activity against EGFR L858R and T790M mutants.
- Reduced potency against wild-type EGFR to aid selectivity studies.
- Maleate salt form for improved handling and stability.
- High purity with RP-HPLC documentation.
- Available in small solid pack sizes and solution formats for assays.
- Intended for in vitro and preclinical research applications.
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Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MM 1 ML
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Asenapine maleate (Org 5222 maleate) is a brain-penetrant atypical antipsychotic. It acts as an antagonist for serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4), and histamine receptors (pKi: 8.2-9.0). This compound is utilized in research for conditions such as schizophrenia and bipolar disorder.
- Antagonist of serotonin, adrenoceptors, dopamine, and histamine receptors.
- Brain-penetrant atypical antipsychotic.
- Used in schizophrenia and bipolar disorder research.
- Higher affinity for 5-HT2C, 5-HT2A, 5-HT2B, 5-HT7, 5-HT6, α2B and D3 receptors relative to D2.
- May offer superior therapeutic effects on anxiety.
- Demonstrates anxiolytic-like effects in animal models.
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Cambridge Isotope Laboratories METHYL METHACRYLATE (2-METHYL-D3, 98%) (+0.1% BHT), 1 G
METHYL METHACRYLATE (2-METHYL-D3, 98%) (+0.1% BHT), 1 G
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