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Filtered Search Results
eMolecules 7283-69-4 | Diisobutyl fumarate | Combi-Blocks, Inc. | MFCD00152430 | 228.288 | C12H20O4 | 98.000 | CC(C)COC(=O)\C=C\C(=O)OCC(C)C | 25g | 603134297
Diisobutyl fumarate | Combi-Blocks, Inc. | 7283-69-4 | MFCD00152430 | 228.288 | C12H20O4 | 98.000 | CC(C)COC(=O)\C=C\C(=O)OCC(C)C | 25g | 603134297
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Apexbio Technology LLC NB-598 Maleate 155294-62-5 50mg
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NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
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Apexbio Technology LLC Flupirtine maleate 75507-68-5 100mg
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Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
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Medchemexpress LLC Avitinib maleate | 1557268-88-8 | 99.9% | 603.60 | 25 MG
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Avitinib maleate is a third-generation, irreversible, and orally active selective EGFR inhibitor. It has IC50 values of 0.18 nM against both EGFR L858R and EGFR T790M, and 7.68 nM against wild-type EGFR. It is also a BTK inhibitor, inducing apoptosis and inhibiting BTK phosphorylation in mantle cell lymphoma. It exhibits anticancer effects.
- Third-generation, irreversible, and orally active selective EGFR inhibitor.
- Potent against EGFR L858R, EGFR T790M, and wild-type EGFR.
- BTK inhibitor.
- Induces apoptosis.
- Inhibits phosphorylation of BTK in mantle cell lymphoma.
- Exhibits anticancer effects.
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eMolecules 217300-17-9 | Ambeed | (Triisopropylsiloxy)methyl chloride | 100mg | 589771798 | A991979 | MFCD05865265 | 222.83 | C10H23ClOSi
ChemScene | Imidazo[12-a]pyrimidin-7-amine | 25mg | 801475938 | CS-0094347 | 462651-80-5 | MFCD09909665 | 134.142 | C6H6N4
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Medchemexpress LLC Setiptiline maleate | 85650-57-3 | 99.9% | 377.43 | 50 MG
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Setiptiline maleate is a serotonin receptor antagonist and a tetracyclic antidepressant (TeCA) that acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).
- Functions as a norepinephrine reuptake inhibitor.
- Acts as an α2-adrenergic receptor antagonist.
- Serves as a serotonin receptor antagonist, targeting 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes.
- Acts as an H1 receptor inverse agonist/antihistamine.
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TARGETMOL CHEMICALS INC ACEPROMAZINE MALEATE 50MG
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Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ACEPROMAZINE MALEATE is a dopamine receptor antagonistpurity: 99%
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Apexbio Technology LLC Rosiglitazone maleate(Synonyms: Avandia, BRL 49653, BRL49653C, Rosiglitazone maleate salt, BRL49653, RGZ, Rosiglizole maleate), 10mM (in 1mL DMSO), CAS: 155141-29-0.
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Rosiglitazone maleate (CAS 155141-29-0) is the maleate salt formulation of rosiglitazone a thiazolidinedione compound targeting the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR ) By selective activation of PPAR rosiglitazone increases insulin sensitivity of peripheral tissues facilitating glucose uptake and reduction of blood glucose levels Due to its insulin-sensitizing activity rosiglitazone maleate serves as an important research tool in diabetes and metabolic syndrome investigations However recent clinical studies also report associations with adverse cardiovascular events fluid retention and anemia underscoring considerations for risk-benefit evaluation in ongoing research
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Medchemexpress LLC Way-100635 maleate | 1092679-51-0 | MFCD01321056 | 99.6% | 538.64 g/mol | C29H38N4O6 | 100 MG
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WAY-100635 maleate is the maleate salt of WAY-100635, a potent and selective 5-HT1A receptor antagonist used for pharmacology and receptor-binding research. It is provided as a high-purity analytical standard suitable for in vitro and in vivo studies.
- Potent 5-HT1A receptor antagonist (IC50 = 0.91 nM; Ki = 0.39 nM).
- High purity: 99.6% (HPLC).
- Molecular weight 538.64 g/mol.
- Molecular formula C29H38N4O6.
- Supplied as a 100 mg vial for research use.
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Medchemexpress LLC Diethyl maleate | 141-05-9 | MFCD00009191 | 98.1% | 172.18 | C8H12O4 | 1g
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Diethyl maleate (DEM) is an orally available effective glutathione (GSH) depletor that crosses the blood-brain barrier Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0 1-0 5 mM Diethyl maleate selectively depletes GSH in liver lung and brain tissues exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO- Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3]
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Medchemexpress LLC Quipazine maleate | 5786-68-5 | 100 MG
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Quipazine maleate is a laboratory chemical from MedChemExpress, identified by catalog number HY-B1495 and CAS number 5786-68-5. It is intended for research use only and for experienced personnel. This product is classified as toxic if swallowed, requiring careful handling.
- Used for laboratory research and manufacturing of substances.
- Stable under recommended storage conditions.
- Shipping at room temperature is acceptable if less than 2 weeks.
- Recommended storage at 4°C, sealed, away from moisture and light.
- If in solvent, store at -80°C for 6 months or -20°C for 1 month.
- Appearance is a solid.
- Melting/freezing point is 151-154 °C.
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eMolecules 147816-23-7 | Medchem Express | Cefcapene pivoxil (hydrochloride) | 25mg | 495800492 | HY-135221 | MFCD00883711 | 604.09 | C23H30ClN5O8S2
Medchem Express | Benzothiohydrazide | 50mg | 533802448 | HY-129943 | 20605-40-7 | MFCD00463358 | 152.220 | C7H8N2S
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Revvity Health Sciences Inc AlphaLISA SureFire Ultra Human Phospho-DAP12 (Tyr91) Detection Kit, 10,000 Assay Points
AlphaLISA SureFire Ultra Human Phospho-DAP12 (Tyr91) Detection Kit, 10,000 Assay Points
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Cayman Chemical BetulIn 3 28-dIacetate 10mg
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A triterpene with antiviral and hepatoprotective activities; inhibits SFV replication in virus-infected Huh7 cells (IC50 = 9.1 µM); improves hepatic function in various rat models of hepatitis at 20 mg/kg
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Selleck Chemical LLC Menadiol Diacetate S4779-25mg
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Menadiol Diacetate (Vitamin K4 Acetomenaphthone Kapilin) is a synthetic hydrophilic menadione compound which is clinically used as hemostasis medicine It induces caspase-3-related apoptosis pathway via mitochondrial dysfunction and DNA fragmentation
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