Carboxylic acid esters
Apexbio Technology LLC Flupirtine maleate 75507-68-5 100mg
Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
Medchemexpress LLC Quipazine maleate | 5786-68-5 | 100 MG
Quipazine maleate is a laboratory chemical from MedChemExpress, identified by catalog number HY-B1495 and CAS number 5786-68-5. It is intended for research use only and for experienced personnel. This product is classified as toxic if swallowed, requiring careful handling.
- Used for laboratory research and manufacturing of substances.
- Stable under recommended storage conditions.
- Shipping at room temperature is acceptable if less than 2 weeks.
- Recommended storage at 4°C, sealed, away from moisture and light.
- If in solvent, store at -80°C for 6 months or -20°C for 1 month.
- Appearance is a solid.
- Melting/freezing point is 151-154 °C.
Apexbio Technology LLC Flupirtine maleate 75507-68-5 1g
Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
Medchemexpress LLC Quipazine (maleate) | 5786-68-5 | 250 MG
Quipazine maleate is a 5-HT agonist that causes behavioral changes such as hyperactivity. It also exhibits weak reversible MAO inhibitory activity.
- Functions as a 5-HT receptor agonist.
- Affects neuronal signaling.
- Induces behavioral changes like hyperactivity.
- Shows weak reversible MAO inhibitory activity.
Medchemexpress LLC Quipazine maleate | 5786-68-5 | >98% | 50 MG
Quipazine maleate is a 5-HT agonist that causes behavioral changes such as hyperactivity. It also shows a weak reversible MAO inhibitory activity. This piperazine-based nonselective serotonin receptor agonist targets several 5-HT receptor subtypes, including 5-HT₂A (pKi ≈ 6.9), 5-HT₂C (≈ 7.27), and 5-HT₂B, as well as showing marked agonist activity at 5-HT₃ (EC₅₀ ≈ 1.0 nM). It has been explored for anti-parkinsonian potential in preclinical settings and is a valuable pharmacological tool for studying serotonin receptor functions.
- 5-HT agonist
- Causes behavioral changes such as hyperactivity
- Weak reversible MAO inhibitory activity
- Nonselective serotonin receptor agonist
- Targets 5-HT₂A, 5-HT₂C, 5-HT₂B, and 5-HT₃ receptors
- Explored for anti-parkinsonian potential
- Valuable pharmacological tool for studying serotonin receptor functions
Medchemexpress LLC Flupirtine (maleate) | 75507-68-5 | 100.0% | 420.39 | 5 MG
Flupirtine (maleate) | 75507-68-5 | 100.0% | 420.39 | 5 MG
Medchemexpress LLC Flupirtine (maleate) | 75507-68-5 | 99.97% | 420.39 | 10 MG
Flupirtine (maleate) | 75507-68-5 | 99.97% | 420.39 | 10 MG
Medchemexpress LLC Flupirtine Maleate | 75507-68-5 | 100.0% | 420.39 | 100 MG
Flupirtine Maleate is an orally active, blood-brain barrier-crossing non-opioid analgesic and neuroprotective agent. It functions as a neuronal potassium channel opener (Kv7 activator), an NMDA receptor antagonist, and a GABA receptor activator. This agent is suitable for research related to focal cerebral ischemia, pain, Alzheimer's disease, or multiple sclerosis.
- Stabilizes blood-brain barrier integrity.
- Reduces oxidative stress and brain leukocyte infiltration.
- Enhances angioneurogenesis.
- Suppresses calcium influx.
- Stabilizes neuronal resting membrane potential.
- Counteracts focal cerebral ischemia.
- Exhibits analgesic and muscle relaxant properties.
- Protects neurons from excitotoxic, ischemic, or cytokine-mediated death.
Medchemexpress LLC Flupirtine Maleate | 75507-68-5 | 99.97% | 420.39 | 500 MG
Flupirtine Maleate | 75507-68-5 | 99.97% | 420.39 | 500 MG
Medchemexpress LLC Flupirtine (Maleate) | 75507-68-5 | 99.9% | 420.39 | 1 ML
Flupirtine Maleate is an orally active, blood-brain barrier-crossing non-opioid analgesic and neuroprotective agent. It exhibits analgesic and muscle relaxant properties, and protects neurons from excitotoxic, ischemic, or cytokine-mediated death.
- Neuronal potassium channel opener (Kv7 activator).
- NMDA receptor antagonist.
- GABA receptor activator.
- Stabilizes blood-brain-barrier integrity.
- Reduces oxidative stress and brain leukocyte infiltration.
- Enhances angioneurogenesis.
- Suppresses calcium influx.
- Stabilizes neuronal resting membrane potential.
- Counteracts focal cerebral ischemia.
- Functions as a non-opioid analgesic without antipyretic or antiphlogistic properties.
- Shows no relevant affinity to opiate receptor.
Medchemexpress LLC Flupirtine maleate | 75507-68-5 | 100.0% | 420.39 | 50 MG
Flupirtine Maleate is an orally active, blood-brain barrier-crossing non-opioid analgesic and neuroprotective agent. It functions as a neuronal potassium channel opener (Kv7 activator), an NMDA receptor antagonist, and a GABA receptor activator. It stabilizes blood-brain-barrier integrity and protects neurons.
- Stabilizes blood-brain-barrier integrity and reduces oxidative stress
- Enhances angioneurogenesis and suppresses calcium influx
- Stabilizes neuronal resting membrane potential
- Counteracts focal cerebral ischemia
- Exhibits analgesic and muscle relaxant properties
- Protects neurons from excitotoxic, ischemic, or cytokine-mediated death
- Functions as a non-opioid analgesic
- Used for research on focal cerebral ischemia, pain, Alzheimer's disease, or multiple sclerosis
Apexbio Technology LLC Flupirtine maleate 75507-68-5 10mM (in 1mL DMSO)
Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
Medchemexpress LLC BGT226 (maleate) | 1245537-68-1 | MFCD22124895 | 99.9% | 650.60 g/mol | C32H29F3N6O6 | 5 MG
BGT226 maleate is a small-molecule PI3K/mTOR dual inhibitor used for research into PI3K signaling and oncology. It shows low-nanomolar potency against PI3K isoforms and mTOR and is used in cell-based and preclinical studies to evaluate antiproliferative and apoptotic effects.
- Inhibits PI3Kα, PI3Kβ, PI3Kγ, and mTOR.
- Exhibits low nanomolar potency in enzymatic assays.
- Demonstrates growth-inhibitory activity in cancer cell models.
- Supplied as the maleate salt for stability.
- High purity suitable for biochemical and cellular assays.
- Available in multiple small pack sizes for research use.