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Filtered Search Results
MEDCHEMEXPRESS LLC Interleukin-2 receptor subunit beta (IL-2R beta/CD122) protein, canine (recombinant, HEK293 hFc) | >95.0% | 2 UG
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Recombinant canine interleukin-2 receptor beta (IL-2Rβ/CD122) extracellular domain expressed in HEK293 cells and provided as a C-terminal human Fc fusion. Supplied as a lyophilized powder for receptor-ligand binding, immunoassays, and functional studies requiring the extracellular portion of canine IL-2Rβ.
- Recombinant extracellular domain of canine IL-2Rβ for biologically relevant binding studies.
- Expressed in HEK293 cells for mammalian glycosylation.
- C-terminal human Fc fusion enhances stability and enables Fc-based detection.
- Supplied lyophilized for long-term storage and convenient reconstitution.
- High purity (>95.0%) suitable for biochemical and immunological assays.
- Low endotoxin (<1 EU/μg) for sensitive cell-based experiments.
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MEDCHEMEXPRESS LLC Interleukin-2 receptor beta (canine), recombinant, Fc-tagged | >95.0% | 50 UG
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Recombinant canine interleukin-2 receptor beta (CD122) extracellular domain produced in HEK293 cells with a C-terminal human Fc tag, supplied lyophilized for research use in immunology and cell signaling. The protein is provided at high purity and formulated for stability and convenient storage and handling.
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MEDCHEMEXPRESS LLC HDHODH-IN-1 100 mg
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HDHODH-IN-1 100MG
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MEDCHEMEXPRESS LLC Tenofovir amibufenamide | 1571076-26-0 | 99.67% | 490.49 | 100 MG
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Tenofovir amibufenamide (HS-10234) is a Tenofovir prodrug, functioning as an orally active antiviral agent. It effectively inhibits HBV and is utilized in studies concerning chronic hepatitis B (CHB). This compound also regulates hepatocyte metabolism.
- Inhibits HBV DNA replication
- Corrects metabolic disorders caused by HBV infection
- Regulates hepatocyte metabolism
- Used for chronic hepatitis B (CHB) study
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MEDCHEMEXPRESS LLC Methyl carnosate | 82684-06-8 | 97.6% | 346.46 | 1 ML
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Methyl carnosate is a diterpene isolated from *Salvia officinalis* or *Rosmarinus officinalis*. It exhibits potent antioxidant and anti-bacterial activity.
- Isolated from natural sources like sage and rosemary.
- Acts as a powerful antioxidant.
- Demonstrates antibacterial properties.
- Has cytotoxic effects on certain cancer cell lines such as MIA PaCa-2 and PANC-1.
- Available in various quantities for research needs.
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MEDCHEMEXPRESS LLC YM-244769 dihydrochloride | 1780390-65-9 | 516.39 | 100 MG
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YM-244769 dihydrochloride is a potent, selective, and orally active Na+/Ca2+ exchanger (NCX) inhibitor. It preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2+ entry mode). This compound efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage.
- Potent, selective, and orally active Na+/Ca2+ exchanger (NCX) inhibitor
- Preferentially inhibits NCX3
- Suppresses unidirectional outward NCX current (Ca2+ entry mode) with IC50s of 18 nM and 50 nM
- Efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage
- Increases urine volume and urinary excretion of electrolytes in mice
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MEDCHEMEXPRESS LLC 1H-Imidazole, 1-dodecyl- | 4303-67-7 | 99.78% | 236.40 | 1 ML
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1H-Imidazole, 1-dodecyl- | 4303-67-7 | 99.78% | 236.40 | 1 ML
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MEDCHEMEXPRESS LLC YM-244769 dihydrochloride | 1780390-65-9 | 516.39 | 50 MG
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YM-244769 dihydrochloride is a potent, selective, and orally active Na+/Ca2+ exchanger (NCX) inhibitor. It preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2+ entry mode). This compound efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage and increases urine volume and urinary excretion of electrolytes in mice.
- Potent and selective Na+/Ca2+ exchanger (NCX) inhibitor
- Preferentially inhibits NCX3 with an IC50 of 18 nM
- Suppresses unidirectional outward NCX current (Ca2+ entry mode)
- Protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage
- Increases urine volume and urinary excretion of electrolytes in mice
- Also inhibits NCX1 (IC50: 68 nM) and NCX2 (IC50: 96 nM)
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MEDCHEMEXPRESS LLC LOSARTAN CARBOXYLIC 50 mg
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LOSARTAN CARBOXYLIC 50MG
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MEDCHEMEXPRESS LLC Aftin-4 | 866893-90-5 | 98.4% | 368.48 | 1 ML
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Aftin-4 is an Amyloid-β42 (Aβ42) inducer. It selectively and potently increases Aβ1-42 in N2a cells, primary neurons, and brain lysates, with an EC50 value around 30 μM. It also increases Aβ1-42 levels in vivo in mice and can provoke sustained toxicity reminiscent of Alzheimer's disease (AD).
- Amyloid-β42 (Aβ42) inducer
- Selectively and potently increases Aβ1-42 in N2a cells, primary neurons, and brain lysates
- Increases Aβ1-42 levels in vivo in mice
- Available in various quantities from 2 mg to 100 mg for in-stock options
- Purity: 98.44%
- Solid appearance, white to off-white color
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years
- Recommended storage for in solvent: -80°C for 2 years, -20°C for 1 year
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MEDCHEMEXPRESS LLC Cgamp disodium | 2407516-83-8 | 98.5% | 718.37 | 10 MG
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Cgamp disodium | 2407516-83-8 | 98.5% | 718.37 | 10 MG
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MEDCHEMEXPRESS LLC YM-244769 | 838819-70-8 | 99.2% | 443.47 | 50 MG
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YM-244769 is a potent, selective, and orally active Na+/Ca2+ exchanger (NCX) inhibitor. It preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2+ entry mode) with IC50s of 18 nM and 50 nM, respectively. It efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage and can increase urine volume and urinary excretion of electrolytes in mice.
- Potent, selective, and orally active Na+/Ca2+ exchanger (NCX) inhibitor.
- Preferentially inhibits NCX3 (IC50 = 18 nM).
- Suppresses unidirectional outward NCX current (Ca2+ entry mode) with an IC50 of 50 nM.
- Efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage.
- Increases urine volume and urinary excretion of electrolytes in mice.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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MEDCHEMEXPRESS LLC 1-Dodecylimidazole | 4303-67-7 | 99.8% | 236.40 | 500 MG
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1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and cytotoxic agent that induces cell death by acid-dependent accumulation in lysosomes, followed by disruption of the lysosomal membrane and release of cysteine proteases into the cytoplasm. It also displays hypocholesterolaemic and broad-spectrum antifungal activities. In vitro studies show its cytotoxicity is pH-dependent, with significantly greater cell killing at pHe 6.0 than at pHe 7.0. In vivo, its hypocholesterolaemic effect is partly due to the inhibition of cholesterol biosynthesis.
- Lysosomotropic detergent
- Cytotoxic agent
- Induces cell death via lysosomal membrane disruption and cysteine protease release
- Exhibits hypocholesterolaemic activity
- Possesses broad-spectrum antifungal activities
- Shows pH-dependent cytotoxicity in vitro
- Inhibits cholesterol biosynthesis in vivo
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MEDCHEMEXPRESS LLC MEDI-570 1mg | 1mg
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MEDI-570 is a humanized antibody expressed in CHO that targets ICOS/CD278 MEDI-570 contains huIgG1 heavy chain and hu light chain with a predicted molecular weight (MW) of 145 kDa The isotype control for MEDI-570 can be referenced as Human IgG1 kappa Isotype Control (HY-P99001)
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MEDCHEMEXPRESS LLC 3-(1H-benzimidazol-1-yl)propan-1-amine | 73866-15-6 | MFCD03093044 | 99.9% | 175.24 | C10H13N3 | 250 MG
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3-(1H-Benzimidazol-1-yl)propan-1-amine is a benzimidazole-containing small-molecule intermediate used in medicinal chemistry and organic synthesis. It functions as a building block for the preparation of pharmacologically active compounds and research reagents. Supplied at high purity with batch-specific quality documentation, it is intended for laboratory research applications and should be handled per safety guidance.
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