Thiazoles
=O)NC(=O)OC(C)(C)C | 250mg | 537700092](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000127964.jpg-250.jpg)
eMolecules 72086-72-7 | (S)-4-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid | Oakwood Chemical | MFCD00076931 | 261.274 | C11H19NO6 | 95.000 | COC(=O)[C@H](CCC(O)=O)NC(=O)OC(C)(C)C | 250mg | 537700092
(S)-4-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid | Oakwood Chemical | 72086-72-7 | MFCD00076931 | 261.274 | C11H19NO6 | 95.000 | COC(=O)[C@H](CCC(O)=O)NC(=O)OC(C)(C)C | 250mg | 537700092
Medchemexpress LLC S-methyl-KE-298 | 143584-75-2 | MFCD31382145 | 98.0% | 252.33 g/mol | C13H16O3S | 10 MG
S-methyl-KE-298 is the active metabolite of KE-298 reported to inhibit matrix metalloproteinase-1 (MMP-1) production in rheumatoid arthritis synovial cells. Supplied as a solid research chemical, it is intended for in vitro studies and characterization and is provided with defined purity and storage conditions.
- Active metabolite of KE-298.
- Inhibits MMP-1 production in rheumatoid arthritis synovial cells.
- High purity (98.0%).
- Solid, white to off-white appearance.
- Molecular formula C13H16O3S; molecular weight 252.33 g/mol.
- Recommended storage conditions for powder and for solutions.
Medchemexpress LLC phospho-ERK1 + 2 (Thr183/Tyr185) Antibody | 50 UL
phospho-ERK1 + 2 (Thr183/Tyr185) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting phospho-ERK1 + 2 (Thr183/Tyr185). It is supplied in 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. This antibody targets the MAP kinase family, involved in cellular processes like proliferation, differentiation, and cell cycle progression. It is activated by upstream kinases, phosphorylating nuclear targets.
- Host: Rabbit
- Clonality: Polyclonal
- Species reactivity: Human, Mouse
- Purity: Affinity purified
- Conjugation: Non-conjugated
- Modification: Phosphorylated
- Isotype: IgG
- Appearance: Liquid
- Applications: WB, ELISA, IHC-P, IHC-F, ICC/IF
eMolecules 72914-19-3 | DTBBPY | Ambeed | MFCD01863731 | 268.404 | C18H24N2 | 98.000 | CC(C)(C)c1ccnc(c1)-c1cc(ccn1)C(C)(C)C | 5g | 524992408
DTBBPY | Ambeed | 72914-19-3 | MFCD01863731 | 268.404 | C18H24N2 | 98.000 | CC(C)(C)c1ccnc(c1)-c1cc(ccn1)C(C)(C)C | 5g | 524992408
eMolecules 76596-53-7 | ChemScene | 1-(3-Bromoisoxazol-5-yl)ethanone | 100mg | 795362638 | CS-0436819 | MFCD18801045 | 189.996 | C5H4BrNO2
ChemScene | 1-(3-Bromoisoxazol-5-yl)ethanone | 100mg | 795362638 | CS-0436819 | 76596-53-7 | MFCD18801045 | 189.996 | C5H4BrNO2
eMolecules 88796-28-5 | AstaTech | ETHYL 5-AMINO-3-METHYLTHIOPHENE-2-CARBOXYLATE | 0.25g | 718066345 | E78251 | 95 | MFCD02257685 | 185.24 | C8H11NO2S
AstaTech | ETHYL 5-AMINO-3-METHYLTHIOPHENE-2-CARBOXYLATE | 0.25g | 718066345 | E78251 | 95.000 | 88796-28-5 | MFCD02257685 | 185.240 | C8H11NO2S
Medchemexpress LLC N-benzyl-N-butyl-4-(phenylsulfamoyl)benzamide | 2244678-29-1 | 98.4% | 50 MG
TH-257 (CAS 2244678-29-1) is a small-molecule allosteric inhibitor of LIM kinase 1 and 2 used as a biochemical research probe to study LIMK-mediated signaling pathways in vitro.
- Potent inhibitor of LIMK1 and LIMK2 with IC50 values of 84 nM and 39 nM.
- Molecular formula C24H26N2O3S and molecular weight 422.54 g/mol.
- High purity (98.36%) suitable for in vitro biochemical studies.
- Supplied as a solid powder and as a 10 mM solution in DMSO; common pack sizes include 5 mg, 10 mg, 50 mg, and 100 mg.
Selleck Chemical LLC (R)-Nepicastat HCl S4926-10mg
(R)-Nepicastat HCl (RS-25560-198) the R-enantiomer of Nepicastat HCl is a potent and selective inhibitor with IC50 of 25 1 nM and 18 3 nM for bovine and human dopamine- -hydroxylase with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors
Medchemexpress LLC YL-939 | 3023925-68-7 | 99.0% | 426.51 g/mol | C25H26N6O | 10 MG
YL-939 is a small-molecule ferroptosis inhibitor that prevents iron-dependent cell death by modulating the PHB2/ferritin/iron axis. It has been characterized as a non-classical ferroptosis inhibitor with demonstrated protective activity in cellular assays.
- Inhibits ferroptosis via the PHB2/ferritin/iron axis.
- Demonstrated cellular activity in vitro against ferroptotic insults.
- High chemical purity (~99.0%) and defined physical properties.
- Off-white to light-yellow solid, molecular weight 426.51 g/mol.
- CAS number 3023925-68-7 for unambiguous identification.
- Soluble in DMSO (100 mg/mL) and amenable to in vivo formulations.
- Store as powder at -20°C; limited stability in solution.
Medchemexpress LLC JH-VIII-157-02 | 1639422-97-1 | 99.0% | 465.55 | 10 MG
JH-VIII-157-02 is a structural analogue of alectinib, functioning as an ALK inhibitor. It demonstrates potent inhibitory activity against various EML4-ALK variants, including those with resistance mutations, and shows selectivity against other kinases. This compound inhibits the growth of several cancer cell lines and exhibits good oral bioavailability, with the ability to penetrate the central nervous system in mice.
- Potent inhibitor of EML4-ALK variants, including G1202R resistance mutation
- Selective against various other kinases such as IRAK1, CLK4, and RET
- Inhibits the growth of cancer cell lines like H3122 and DFCI76
- Good oral bioavailability in mice
- Penetrates the central nervous system in mice
Medchemexpress LLC Blue Tetrazolium | 1871-22-3 | MFCD00040933 | 99.8% | 100 MG
Blue Tetrazolium is a blue dye used in microbial research that can be reduced into blue tetrazolium formazan (BTF). It acts as a substrate to determine the activity of succinate dehydrogenase (SDH) in yeast strains. BTF can be extracted from cells using DMSO, and its absorption spectrum can be analyzed with a broad wavelength range of 480-600 nm, and a maximal absorbance at 540 nm.
- Used as a blue dye in microbial research.
- Reducible to blue tetrazolium formazan (BTF).
- Determines succinate dehydrogenase (SDH) activity in yeast strains.
- Absorption spectrum of BTF shows maximal absorbance at 540 nm.
- Functions as a novel corrosion inhibitor for cold-rolled steel in hydrochloric acid solutions.
Medchemexpress LLC Tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate | 571188-59-5 | 99.97% | 278.36 | 50 G
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is a drug intermediate used for the synthesis of various active compounds. It is for research use only and not sold to patients.
- Drug intermediate
- For synthesis of various active compounds
eMolecules 1251929-90-4 | 2-hydroxy-2-(4-methylthiazol-2-yl)propanehydrazide | 250mg
Pharmablock | O3-tert-butyl O8-methyl 3-azabicyclo[3.2.1]octane-38-dicarboxylate | 25mg | 590288775 | PBLG0009 | 1403766-87-9 | MFCD23106312 | 269.341 | C14H23NO4
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eMolecules 71574-33-9 | 4,5-Dimethylthiazol-2-amine hydrochloride | Oakwood Chemical | MFCD00012711 | 164.650 | C5H9ClN2S | 98.000 | Cl.Cc1nc(N)sc1C | 1g | 537714270
4,5-Dimethylthiazol-2-amine hydrochloride | Oakwood Chemical | 71574-33-9 | MFCD00012711 | 164.650 | C5H9ClN2S | 98.000 | Cl.Cc1nc(N)sc1C | 1g | 537714270
Medchemexpress LLC N-benzyl-4-(N-benzylsulfamoyl)benzamide | 313520-94-4 | MFCD00990583 | 99.0% | C21H20N2O3S | 10MG
TH-263 is a diaryl sulfonamide derivative (CAS 313520-94-4) that is inactive toward both LIMK1 and LIMK2 and is used as a negative control for the LIMK inhibitor TH-257. It is supplied as a high-purity solid (molecular formula C21H20N2O3S, MW 380.46 g/mol), soluble in DMSO, and intended for use as a selectivity control in biochemical and cell-based assays.
- Diaryl sulfonamide derivative inactive toward LIMK1 and LIMK2.
- High purity: 99.0%.
- Suitable as a negative control in biochemical and cell-based assays.
- Soluble in DMSO for in vitro applications.
- Powder stable at -20°C; solutions stored at -80°C for extended stability.