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Filtered Search Results
Medchemexpress LLC (4-(Thiazol-2-ylcarbamoyl)piperidine-1-carbonyl)-L-leucine | 1814897-92-1 | 99.6% | 368.45 | 5 MG
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This chemical compound, (4-(Thiazol-2-ylcarbamoyl)piperidine-1-carbonyl)-L-leucine, is designed for laboratory use and the manufacture of substances. It is stable under recommended storage conditions and offers high purity.
- High purity of 99.64%
- Suitable for laboratory applications
- Stable under recommended storage conditions
- Not classified as a hazardous substance or mixture
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BIOHIPPO AAV-TH-3XFlag-WPRE-hGH-polyA
Recombinant adeno associated virus expressing 3XFlag under the TH promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Medchemexpress LLC 4-[2-(2-fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyridine | 1784751-19-4 | MFCD29924749 | 99.9% | 333.33 g/mol | C20H13F2N3 | 50 MG
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TA-02 is a small-molecule p38 MAPK inhibitor used in biochemical and cell-based research. As an analog of SB 203580, it exhibits potent activity (IC50 ≈ 20 nM) and preferential inhibition of TGFBR-2. The compound is supplied as a high-purity solid suitable for laboratory studies involving kinase signaling modulation.
- Potent p38 MAPK inhibition (IC50 ≈ 20 nM).
- Preferential inhibition of TGFBR-2.
- High purity solid suitable for research applications.
- Compact pack sizes available for small-scale studies.
- Molecular weight ~333.33 g/mol; formula C20H13F2N3.
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Medchemexpress LLC Pyrazoline-based chloroacetamide | 99.6% | 404.89 g·mol⁻¹ | C24H21ClN2O2 | 10 MG
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MM-02-57 is a covalent small-molecule recruiter that targets the DDB1 adaptor to engage the CUL4A ubiquitin ligase complex for targeted protein degradation studies. It is provided as a solid powder intended for laboratory research use only.
- Covalent recruiter of DDB1 for CUL4A adaptor engagement.
- Designed for use in targeted protein degradation and chemoproteomics research.
- Pyrazoline-based chloroacetamide scaffold with cysteine-reactive electrophile.
- Molecular weight 404.89 g·mol⁻¹; chemical formula C24H21ClN2O2.
- Supplied as a solid powder with cold storage recommendations for stability.
- High reported purity from distributor analyses, suitable for biochemical assays.
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Medchemexpress LLC (R)-Phenyl (5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)carbamate | 2135871-21-3 | 99.48% | 435.43 | 5 MG
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(R)-Phenyl (5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)carbamate is a drug intermediate used for the synthesis of various active compounds.
- For research use only
- Drug intermediate for synthesis
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eMolecules 189333-03-7 | tert-Butyl 2,9-diazaspiro[5.5]undecane-2-carboxylate | Ambeed | MFCD11223510 | 254.374 | C14H26N2O2 | 98.000 | CC(C)(C)OC(=O)N1CCCC2(CCNCC2)C1 | 250mg | 586028511
tert-Butyl 2,9-diazaspiro[5.5]undecane-2-carboxylate | Ambeed | 189333-03-7 | MFCD11223510 | 254.374 | C14H26N2O2 | 98.000 | CC(C)(C)OC(=O)N1CCCC2(CCNCC2)C1 | 250mg | 586028511
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Medchemexpress LLC 4-(2-(4-(benzyloxy)phenyl)acetamido)-1-(3'-chloro-[1,1'-biphenyl]-4-carbonyl)piperidine-4-COOH | 100.0% | 583.07 g/mol | C34H31ClN2O5 | 10 MG
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YL-365 is a small-molecule GPR34 agonist used in preclinical research on pain and cancer. It has molecular formula C34H31ClN2O5, a molecular weight of 583.07 g/mol, and an analytical purity of 99.96%. The compound is supplied as a solid in milligram quantities and should be stored at 4°C protected from light; in solvent, store at -80°C for up to 6 months or -20°C for up to 1 month.
- Acts as a GPR34 agonist to probe lysophosphatidylserine receptor signaling.
- Suitable for pain and cancer preclinical studies.
- High analytical purity for consistent experimental outcomes.
- Available in small milligram quantities for dosing flexibility.
- Stable when stored under recommended conditions and protected from light.
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Medchemexpress LLC Met kinase-IN-2 | 2101241-90-9 | 98.4% | 50 MG
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MET kinase-IN-2 is a potent, selective, and orally bioavailable MET kinase inhibitor with an IC50 of 7.4 nM. It exhibits antitumor activity.
- Potent and selective MET kinase inhibitor
- Orally bioavailable
- Exhibits antitumor activity
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eMolecules 1089724-08-2 | 4-(ethylamino)-2-(methylthio)-5-Pyrimidinecarboxylic acid | MFCD12911522 | 1g
Medchem Express | Pyr3 | 5mg | 446259346 | HY-108465 | 1160514-60-2 | MFCD00178741 | 456.630 | C16H11Cl3F3N3O3
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Medchemexpress LLC Methyltetrazine-amine hydrochloride | 1596117-29-1 | MFCD32061909 | 99.7% | C10H12ClN5 | 10MG
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Methyltetrazine-amine hydrochloride is a tetrazine-containing small-molecule reagent used for inverse electron demand Diels-Alder (iEDDA) bioorthogonal click chemistry. It facilitates rapid and selective conjugation to strained dienophiles for site-specific labeling and bioconjugation of biomolecules.
- High chemical purity (99.7%) suitable for analytical and preparative workflows.
- Hydrochloride salt form improves stability and handling as a solid.
- Reactive tetrazine moiety enables fast, catalyst-free iEDDA reactions with dienophiles.
- Suitable for site-specific biomolecule labeling and bioconjugation.
- Available in small research pack sizes for laboratory use.
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Medchemexpress LLC TH-6 | 3031349-25-1 | 95.0% | 429.44 | 50 MG
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TH-6 is a potent HDAC inhibitor that shows anti-tumor activity. It inhibits cell migration and invasion, and induces apoptosis and cell cycle arrest at G2/M phase.
- Potent HDAC inhibitor with specific IC50s for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8.
- Inhibits cell migration and invasion.
- Induces apoptosis and cell cycle arrest at G2/M phase.
- Shows anti-tumor activity in mice models.
- Exhibits antiproliferative activities in various cancer cell lines and normal human lung cells.
- Inhibits tubulin polymerization.
- Increases expression of Ac-α-Tubulin and AC-Histone H3 in HepG2 cells.
- Shows favorable liver microsomal stability in vitro.
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Medchemexpress LLC R -2- Thiazol-2-Yl 250Mg | 250MG-HY-W077686A
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R -2- Thiazol-2-Yl 250Mg
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eMolecules 224311-51-7 | JOHNPHOS | AstaTech | MFCD01862440 | 298.410 | C20H27P | 98.000 | CC(C)(C)P(c1ccccc1-c1ccccc1)C(C)(C)C | 5g | 392629757
JOHNPHOS | AstaTech | 224311-51-7 | MFCD01862440 | 298.410 | C20H27P | 98.000 | CC(C)(C)P(c1ccccc1-c1ccccc1)C(C)(C)C | 5g | 392629757
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eMolecules 111769-26-7 | (R)-Tetrahydrofuran-3-amine | Accela ChemBio | MFCD08234424 | 87.122 | C4H9NO | 97.000 | N[C@@H]1CCOC1 | 0.25g | 778445128
(R)-Tetrahydrofuran-3-amine | Accela ChemBio | 111769-26-7 | MFCD08234424 | 87.122 | C4H9NO | 97.000 | N[C@@H]1CCOC1 | 0.25g | 778445128
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Medchemexpress LLC Jh-viii-157-02 | 1639422-97-1 | 98.98% | 465.55 | 25 MG
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JH-VIII-157-02 is a structural analogue of alectinib, functioning as an ALK inhibitor. It exhibits an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells. It also potently inhibits various EML4-ALK mutants and shows selectivity at other kinases.
- Inhibits EML4-ALK G1202R (IC50, 2 nM).
- Potent inhibition of EML4-ALKwt, EAC1156Y, EAF1174L, EAS1206Y (IC50, 2 nM), EAG1269A (IC50, 3 nM), EAL1196M (IC50, 58 nM), EA1151Tins (IC50, 107 nM), and EAL1152R (IC50, 196 nM).
- Selective inhibition of other kinases including IRAK1, CLK4, RET, RET V804L, RET V804M and IRAK 4.
- Inhibits growth in cancer cell lines like H3122 and DFCI76 (L1152R) with EC50s of 5 and 19 nM.
- Good oral bioavailability at 10 mg/kg in mice.
- Penetrates the CNS of mice.
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