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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences HuR-ARE Interaction Inhibi
A cell-permeable 2H-chromen-2-one based compound that competitively binds to Hu antigen R (HuR Ki 350 nM) and disrupts the interaction of HuR and adenine- and uridine-rich element (ARE) of target mRNAs. Displays dose-dependent binding to full-length HuR protein and to RRM1/2 fragment. Exhibits cytotoxicity towards tumor cells and reduces their viability (IC50 28.9 and 18.2 181M for HCT-116 and MioPaCa2 cells respectively). Has much reduced effect on normal WI-38 and CCD 841 CoN cells. Shown to induce cleavage of poly (ADP-ribose) polymerase and pro-caspase 3 (~ 50 181M) and reduce the half-life of Bcl-2 Msi1 and XIAP in HCT-116 cells (~20 181M) treated with actinomycin D (5 181g/ml).Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Sigma Aldrich Fine Chemicals Biosciences sequence 9-deoxyribonucleotide
Random Nonamers are random sequences of nine deoxyribonucleotides (9-mers) used to prime mRNA with or without a poly(A) tail. Random nonamers may be used as universal non-specific primers.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Sigma Aldrich Fine Chemicals Biosciences DuranR GL 45 connection sy
GL 45 screw cap with either two or three ports that have GL 14 thread. This is a flexible modular system which has four different hose diameters available 1.6 mm 3.0 mm 3.2 mm and 6.0 mm that can be connected.Sterile pressure equalization is possible through use of membrane filter.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Sigma Aldrich Fine Chemicals Biosciences AccumaxTM solution sterile
AccumaxTM SOLUTIONon sterile
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Sigma Aldrich Fine Chemicals Biosciences PKCalpha Protein active 10
Recombinant full-length human PKCalpha containing N-terminal His6 tagPKC Lipid activator (Catalog 20-133) is required for use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Med Vet International Set Solution interlink Continu-Flo 3 in Ea
Continu-Flo solution sets help you administer necessary fluids to patients Single use to prevent cross-contamination
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Sigma Aldrich Fine Chemicals Biosciences Accessory for CorningR Coo1EA
Accessory for CorningR Coo1EA
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Grainger Auto Drain Valve 208-240V 3/8
Auto Drain Valve 208-240V 3/8 In.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Lauda Brinkmann Lp LAUDA BRINKMANN LP
NC3909849 MC600 MICROCOOL NATREF 115V
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Sigma Aldrich Fine Chemicals Biosciences HiTrapR Protein G High Per
HiTrap(R) Protein G HP columns are prepacked with Protein G Sepharose(R) High Performance for fast easy separations of IgG from different species and subclasses.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Cerulean BUBBLEMETER 60-150ML BRUGHAR
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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NC2742027 BUBBLEMETER 60-150ML BRUGHAR
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Julabo USA Inc PRESTO W40 Circulator 208V
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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JULABO PRESTO Highly Dynamic Temperature Control Systems for highly precise temperature control of external applications Systems offer rapid heating and cooling rates The hydraulically sealed heat exchanger design affords a wide working temperature range without changing fluids All units feature a color TFT touch screen interface for unit operation external integration and programming Instruments cover a working temperature range of -85 to 250C Up to three user levels with password management Systems incorporate USB (host and device) Ethernet SD-card slot RS232 port stand-by input and Pt100 external temperature sensor port The graphite bearing centrifugal pressure pump is lubricated by the bath fluid All models (except for A30) can operate under pressure control to safeguard pressure sensitive applications (such as jacketed glass reactors) Air and water-cooled versions available Additional accessories available
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Julabo USA Inc PRESTO A80 Circulator
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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JULABO PRESTO Highly Dynamic Temperature Control Systems for highly precise temperature control of external applications Systems offer rapid heating and cooling rates The hydraulically sealed heat exchanger design affords a wide working temperature range without changing fluids All units feature a color TFT touch screen interface for unit operation external integration and programming Instruments cover a working temperature range of -85 to 250C Up to three user levels with password management Systems incorporate USB (host and device) Ethernet SD-card slot RS232 port stand-by input and Pt100 external temperature sensor port The graphite bearing centrifugal pressure pump is lubricated by the bath fluid All models (except for A30) can operate under pressure control to safeguard pressure sensitive applications (such as jacketed glass reactors) Air and water-cooled versions available Additional accessories available
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Research Products International Corp Replacmnt Lid Iso Frze Chiller
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Replacement lid for Iso-Freeze PCR Tube Chiller (248004)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Grainger Sulfate LR Mini Kit
Sulfate LR Mini Kit
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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