ELISA Substrates and Reagents
ABclonal Technology Phospho-AMPKα1-S485 Rabbit pAb
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
American Research Products Inc Human HSPA1A ELISA Kit
This Human Heat Shock 70kDa Protein 1A (HSPA1A) ELISA Kit is a precoated Sandwich ELISA assay designed to detect and quantify the target analyte in serum plasma tissue homogenates cell lysates cell culture supernatants and other biological fluids This product is for Research Use Only
Medchemexpress LLC Alpha-2-HS-glycoprotein (fetuin-A), recombinant mouse, His tag | >95.0% | 100UG
AHSG/Fetuin-A Protein, Mouse (HEK293, His) is a recombinant phosphorylated glycoprotein produced in HEK293 cells and supplied as a lyophilized His-tagged protein for research use. The protein exhibits mammalian glycosylation, high purity, and low endotoxin, and includes recommended reconstitution and storage conditions to preserve activity and reproducibility.
- Expressed in HEK293 cells to retain mammalian post-translational modifications.
- C-terminal His tag for detection and purification applications.
- Purity greater than 95% by reducing SDS-PAGE.
- Endotoxin level less than 1 EU/μg for low immunogenic interference.
- Lyophilized formulation with defined buffer for stability and handling.
- Recommended storage at -20°C and aliquoting for extended stability.
- Not recommended to reconstitute below 100 μg/mL; add carrier protein for long-term storage.
ABclonal Technology Phospho-ERK1-T202 + ERK2-T185 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Cayman Chemical DecorIn Long Isoformhumn100ug
Source: Recombinant human C-terminal His-tagged decorin expressed in HEK293 cells • Amino acids: 17-359 • MW: 39.4 kDa
ABclonal Technology Phospho-PPP1R12A-S668 Rabbit pAb
Myosin phosphatase target subunit 1 (MBS) is a subunit of myosin phosphatase, which regulates the actin-myosin interaction downstream of the GTPase Rho. RhoA, in its active GTP-bound form, interacts with MBS to control myosin light chain (MLC) phosphorylation, affecting smooth muscle contraction and nonmuscle cell function. RhoA activates Rho-kinase, which phosphorylates MBS and inactivates myosin phosphatase. Overexpression or activation of RhoA increases MBS and MLC phosphorylation. This pathway regulates the balance of actin and myosin interaction. Several isoforms of this gene have been identified due to alternative splicing.
ABclonal Technology Phospho-GSK3α-S21 Rabbit pAb
This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimers disease.
ABclonal Technology pJNK1/2/3-T183/Y185/T221/Y223
The protein encoded by this gene is a member of the MAP kinase family MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development This kinase is activated by various cell stimuli and targets specific transcription factors and thus mediates immediate-early gene expression in response to cell stimuli The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis This kinase is also involved in UV radiation induced apoptosis which is thought to be related to cytochrom c-mediated cell death pathway Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation apoptosis and differentiation Several alternatively spliced transcript variants encoding distinct isoforms have been reported [provided by RefSeq Apr 2016]
Medchemexpress LLC Discoidin domain-containing receptor 2, rat | >95.0% | 5 UG
DDR2 is a recombinant rat-derived discoidin domain receptor 2 protein expressed in HEK293 cells with a C-terminal His tag. It is a receptor tyrosine kinase involved in tissue remodeling and extracellular matrix signaling, supplied for research applications such as biochemical assays, signaling studies, and antibody validation.
- Expressed in HEK293 cells.
- Derived from rat sequence.
- C-terminal His tag for detection and purification.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Available in small research quantities suitable for assay development.
- Suitable for biochemical assays, signaling studies, and antibody validation.
Miltenyi Biotec, Inc. SARS-CoV-2 Furin Cleavage Site Control-Biotin
SARS-CoV-2 antigen for investigation of virus-specific immune responses.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
ABclonal Technology Phospho-MEK1-T292 Rabbit pAb
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.