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Instruments designed to measure and/or control the flow of test liquids and gases. Products include process flow computers, flow measurement controllers, and process flowmeters and may be able to record flow data digitally.
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ARS-853 is a selective covalent KRAS(G12C) inhibitor that inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation ARS-853 also induces apoptosis
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Wall style Quick release female DISS flowmeter, can hook right to male DISS i.e. ‘H’ tank regulator. Dial flowmeter 1-15 LPM. Outlet end is a male DISS fitting.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ARS-853 is a selective covalent KRAS(G12C) inhibitor that inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation ARS-853 also induces apoptosis
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ARS-1630 is a novel inhibitor of mutant K-ras G12C, derived from patent WO 2015054572 A1. It is characterized as a less active enantiomer of ARS-1620. This compound targets mutant K-ras G12C, which is considered potentially druggable through allele-specific covalent targeting of Cys-12 near an inducible allosteric switch II pocket. This approach relies on the active cycling of KRAS G12C between its active-GTP and inactive-GDP conformations, as the accessibility of the switch II pocket is limited to the GDP-bound state.
Specifically inhibits mutant K-ras G12C.
It is a less active enantiomer of ARS-1620.
Molecular weight: 430.84.
Chemical formula: C21H17ClF2N4O2.
Appears as a white to yellow solid.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ARS-1323 is a potent KRAS G12C inhibitor. It specifically binds to the cysteine residue on the mutant K-Ras protein, locking it in the GDP-bound conformation and effectively blocking K-Ras activation and downstream signaling pathways. This compound is valuable for investigating signal transduction mechanisms and growth characteristics of tumor cells driven by K-Ras G12C.
KRAS G12C inhibitor
Specifically binds to the cysteine residue on the mutant K-Ras protein
Blocks K-Ras activation and downstream signaling pathways
Useful for investigating signal transduction mechanisms
Useful for studying growth characteristics of K-Ras G12C driven tumor cells
Supplied as a white to off-white solid
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ARS-1323 is a KRAS G12C inhibitor that specifically binds to the cysteine residue on the mutant K-Ras protein. This action locks K-Ras in its GDP-bound conformation, blocking activation and downstream signaling pathways. It is suitable for investigating signal transduction mechanisms and growth characteristics in tumor cells driven by K-Ras G12C.
Inhibits KRAS G12C
Blocks K-Ras activation and downstream signaling
Investigates signal transduction mechanisms and growth characteristics
Reduces uptake of [18F]PFPMD by KRAS G12C-mutant H358 NSCLC cells
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
This full range of direct-reading flowmeters provide a robust solution for your laboratory that eliminates the need for reading conversions. Valved flowmeters have a valve mounted at the inlet (bottom) of the flowmeter. This arrangement is typically used for positive pressure applications for liquids and gases. The valve can be reconfigured to mount at the outlet (top), often for vacuum applications.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ARS-1630 is a novel inhibitor of mutant K-ras G12C, whose properties are derived from patent WO 2015054572 A1. It is a less active enantiomer of ARS-1620 and is supplied as a white to yellow solid.
Inhibits mutant K-ras G12C
Less active enantiomer of ARS-1620
Available in solid form
White to yellow appearance
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Aluminum is economical and good for general use with noncorrosive gases and liquids. Brass is economical and good for use with water. Stainless steel withstands higher temperature and pressure and features excellent chemical compatibility. Valved meters have valves mounted at the bottom/inlet, typically used for positive pressure with liquids and gases. The valve can be reconfigured to mount at the top/outlet, often for vacuum applications. All correlated flowmeters come with data sheets for water and air at standard temperature and pressure (STP).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More