Hydroxybenzoic Acid Derivatives
4-Fluorobenzoyl Chloride 97.0+%, TCI America™
CAS: 403-43-0 Molecular Formula: C7H4ClFO Molecular Weight (g/mol): 158.556 MDL Number: MFCD00000684 InChI Key: CZKLEJHVLCMVQR-UHFFFAOYSA-N Synonym: benzoyl chloride, 4-fluoro,p-fluorobenzoyl chloride,benzoyl chloride, p-fluoro,p-fluorobenzoic acid chloride,4-fluorobenzoylchloride,fluorobenzoyl 4-chloride,4-fluorobenzoic acid chloride,p-fluorobenzoylchloride,p-fluorobenzoyl choride,4-flurobenzoyl chloride PubChem CID: 67879 IUPAC Name: 4-fluorobenzoyl chloride SMILES: C1=CC(=CC=C1C(=O)Cl)F
2,4,6-Trichlorobenzoic Acid 98.0+%, TCI America™
CAS: 50-43-1 Molecular Formula: C7H3Cl3O2 Molecular Weight (g/mol): 225.449 MDL Number: MFCD00060699 InChI Key: RAFFVQBMVYYTQS-UHFFFAOYSA-N Synonym: benzoic acid, 2,4,6-trichloro,unii-0bwg1hx6ck,2,4,6-trichlorobenzoicacid,2,4,6-trichloro-benzoic acid,0bwg1hx6ck,2,4,6-trichlorbenzoes,pubchem18496,acmc-209kme,2,4,6-trichlorobbenzoicacid,ksc270e7f PubChem CID: 5764 IUPAC Name: 2,4,6-trichlorobenzoic acid SMILES: C1=C(C=C(C(=C1Cl)C(=O)O)Cl)Cl
Methyl 3-Bromo-4-methylbenzoate 98.0+%, TCI America™
CAS: 104901-43-1 Molecular Formula: C9H9BrO2 Molecular Weight (g/mol): 229.073 MDL Number: MFCD00144769 InChI Key: MASRAGFWFYHMFI-UHFFFAOYSA-N Synonym: 3-bromo-4-methylbenzoic acid methyl ester,methyl 3-bromo-p-toluate,methyl3-bromo-4-methylbenzoate,benzoic acid, 3-bromo-4-methyl-, methyl ester,3-bromo-p-toluic acid methyl ester,3-bromo-4-methyl methyl benzoate,3-bromo-4-methyl-benzoic acid methyl ester,pubchem3967,acmc-2098dw,methyl 3-bromo4-methylbenzoate PubChem CID: 7015747 IUPAC Name: methyl 3-bromo-4-methylbenzoate SMILES: CC1=C(C=C(C=C1)C(=O)OC)Br
Methyl 4-Chlorobenzoate 98.0+%, TCI America™
CAS: 1126-46-1 Molecular Formula: C8H7ClO2 Molecular Weight (g/mol): 170.59 MDL Number: MFCD00000621 InChI Key: LXNFVVDCCWUUKC-UHFFFAOYSA-N Synonym: methyl p-chlorobenzoate,4-chlorobenzoic acid methyl ester,benzoic acid, 4-chloro-, methyl ester,unii-m0u80j80va,benzoic acid, p-chloro-, methyl ester,methyl-p-chlorobenzoate,p-chlorobenzoic acid methyl ester,methyl-4-chlorobenzoate,4-chloro-benzoic acid methyl ester,decitabine related compound d PubChem CID: 14307 IUPAC Name: methyl 4-chlorobenzoate SMILES: COC(=O)C1=CC=C(Cl)C=C1
Methyl 4-Bromo-3-methylbenzoate 97.0+%, TCI America™
CAS: 148547-19-7 Molecular Formula: C9H9BrO2 Molecular Weight (g/mol): 229.073 MDL Number: MFCD00673014 InChI Key: GTZTYNPAPQKIIR-UHFFFAOYSA-N Synonym: 4-bromo-3-methylbenzoic acid methyl ester,methyl4-bromo-3-methylbenzoate,methyl 4-bromo-m-toluate,4-bromo-3-methyl-benzoic acid methyl ester,methyl 4-bromo-3-methyl-benzoate,4-bromo-m-toluic acid methyl ester,benzoic acid, 4-bromo-3-methyl-, methyl ester,2-bromo-5-methoxycarbonyl toluene,3-methyl-4-bromobenzoic acid methyl ester,pubchem3970 PubChem CID: 3294148 IUPAC Name: methyl 4-bromo-3-methylbenzoate SMILES: CC1=C(C=CC(=C1)C(=O)OC)Br
4-Fluorobenzoyl chloride, 98%
CAS: 403-43-0 Molecular Formula: C7H4ClFO Molecular Weight (g/mol): 158.556 MDL Number: MFCD00000684 InChI Key: CZKLEJHVLCMVQR-UHFFFAOYSA-N Synonym: benzoyl chloride, 4-fluoro,p-fluorobenzoyl chloride,benzoyl chloride, p-fluoro,p-fluorobenzoic acid chloride,4-fluorobenzoylchloride,fluorobenzoyl 4-chloride,4-fluorobenzoic acid chloride,p-fluorobenzoylchloride,p-fluorobenzoyl choride,4-flurobenzoyl chloride PubChem CID: 67879 IUPAC Name: 4-fluorobenzoyl chloride SMILES: C1=CC(=CC=C1C(=O)Cl)F
Methyl 3-bromo-4-methylbenzoate, 99%
CAS: 104901-43-1 Molecular Formula: C9H9BrO2 Molecular Weight (g/mol): 229.073 MDL Number: MFCD00144769 InChI Key: MASRAGFWFYHMFI-UHFFFAOYSA-N Synonym: 3-bromo-4-methylbenzoic acid methyl ester,methyl 3-bromo-p-toluate,methyl3-bromo-4-methylbenzoate,benzoic acid, 3-bromo-4-methyl-, methyl ester,3-bromo-p-toluic acid methyl ester,3-bromo-4-methyl methyl benzoate,3-bromo-4-methyl-benzoic acid methyl ester,pubchem3967,acmc-2098dw,methyl 3-bromo4-methylbenzoate PubChem CID: 7015747 IUPAC Name: methyl 3-bromo-4-methylbenzoate SMILES: CC1=C(C=C(C=C1)C(=O)OC)Br
4-Fluorobenzoyl chloride, 98%
CAS: 403-43-0 Molecular Formula: C7H4ClFO Molecular Weight (g/mol): 158.56 MDL Number: MFCD00000684 InChI Key: CZKLEJHVLCMVQR-UHFFFAOYSA-N Synonym: benzoyl chloride, 4-fluoro,p-fluorobenzoyl chloride,benzoyl chloride, p-fluoro,p-fluorobenzoic acid chloride,4-fluorobenzoylchloride,fluorobenzoyl 4-chloride,4-fluorobenzoic acid chloride,p-fluorobenzoylchloride,p-fluorobenzoyl choride,4-flurobenzoyl chloride PubChem CID: 67879 IUPAC Name: 4-fluorobenzoyl chloride SMILES: C1=CC(=CC=C1C(=O)Cl)F
Salicylic acid, sodium salt, 99+%, Thermo Scientific Chemicals
CAS: 54-21-7 Molecular Formula: C7H5NaO3 Molecular Weight (g/mol): 160.104 MDL Number: MFCD00002440 InChI Key: ABBQHOQBGMUPJH-UHFFFAOYSA-M Synonym: sodium salicylate,sodium 2-hydroxybenzoate,salsonin,clin,enterosalicyl,enterosalil,entrosalyl,glutosalyl,kerasalicyl,magsalyl PubChem CID: 16760658 ChEBI: CHEBI:9180 IUPAC Name: sodium;2-hydroxybenzoate SMILES: C1=CC=C(C(=C1)C(=O)[O-])O.[Na+]
Medchemexpress LLC 4-Hydroxymethylpyrazole | 25222-43-9 | 99.74% | 98.11 | 25 G
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole, resulting from hepatic oxidative metabolism. Its plasma concentration correlates positively with the administered Fomepizole dosage, and it has a relatively short half-life. It inhibits alcohol dehydrogenase (ADH) in humans and monkeys, although its in vivo impact is considered negligible due to a significantly higher inhibition constant than Fomepizole.
- Functions as an endogenous metabolite
- Demonstrates inhibitory effects on alcohol dehydrogenase
- Suitable for research in metabolic diseases and natural products
Medchemexpress LLC 4-hydroxymethylpyrazole | 25222-43-9 | 99.7% | 98.11 | 10 G
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole produced through hepatic oxidative metabolism. It exhibits a plasma concentration positively correlated with the administered dosage of Fomepizole and has a relatively short half-life. It also demonstrates inhibitory effects on alcohol dehydrogenase (ADH) in both humans and monkeys, though its inhibition constant is significantly higher than Fomepizole, making its in vivo impact negligible.
- Primary metabolite of Fomepizole
- Exhibits plasma concentration positively correlated with Fomepizole dosage
- Relatively short half-life
- Demonstrates inhibitory effects on alcohol dehydrogenase (ADH)
- For research use only
Medchemexpress LLC 4-Hydroxymethylpyrazole | 25222-43-9 | 99.7% | 98.11 | 100 G
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole, produced through hepatic oxidative metabolism. It exhibits a plasma concentration positively correlated with the administered dosage of Fomepizole and has a relatively short half-life. This compound demonstrates inhibitory effects on alcohol dehydrogenase (ADH) in humans and monkeys, though its in vivo impact is negligible due to a significantly higher inhibition constant compared to Fomepizole. It is intended for research use only.
- Primary metabolite of Fomepizole
- Produced through hepatic oxidative metabolism
- Exhibits plasma concentration positively correlated with administered dosage
- Relatively short half-life
- Demonstrates inhibitory effects on alcohol dehydrogenase (ADH)
- For research use only
Medchemexpress LLC 4-Hydroxymethylpyrazole | 25222-43-9 | 99.7% | 98.11 | 5 G
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole, produced through hepatic oxidative metabolism. It has a plasma concentration positively correlated with the administered dosage of Fomepizole and a relatively short half-life. It inhibits alcohol dehydrogenase (ADH) in humans and monkeys, but its inhibition constant is significantly higher than Fomepizole's, rendering its in vivo impact negligible.
- Primary metabolite of Fomepizole
- Produced through hepatic oxidative metabolism
- Plasma concentration positively correlated with administered dosage
- Relatively short half-life
- Inhibits alcohol dehydrogenase (ADH) in humans and monkeys
- In vivo impact negligible
Medchemexpress LLC KH-4-43 | 2813310-07-3 | 99.7% | 422.74 | 1 ML
KH-4-43 is an inhibitor of E3 CRL4, inhibiting its core ligase complex and demonstrating anticancer activity. It is suitable for research use only.
- Inhibits E3 CRL4 core ligase complex
- Demonstrates anticancer activity
- Binding Kd to E3 ROC1-CUL4A CTD is 83 nM
- Binding Kd to ROC1-CUL1 CTD is 9.4 μM
Medchemexpress LLC 4-Hydroxymethylpyrazole | 25222-43-9 | MFCD06797673 | 99.7% | 98.11 | 50 G
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole (HY-B0876) and is produced through hepatic oxidative metabolism. It shows a plasma concentration that correlates with the administered dosage of Fomepizole and has a relatively short half-life. While it inhibits alcohol dehydrogenase (ADH) in humans and monkeys, its inhibition constant is significantly higher than that of Fomepizole, making its in vivo impact negligible.
- Primary metabolite of Fomepizole.
- Exhibits plasma concentration positively correlated with dosage.
- Demonstrates inhibitory effects on alcohol dehydrogenase (ADH) in both humans and monkeys.
- For research use only.