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Filtered Search Results
Medchemexpress LLC Bromo-PEG2-alcohol | 57641-66-4 | 99.0% | C4H9BrO2 | 10 G
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Bromo-PEG2-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed to exploit the intracellular ubiquitin-proteasome system, selectively degrading target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Molecular weight: 169.02
- Chemical formula: C4H9BrO2
- CAS number: 57641-66-4
- Purity: 98.98%
- Appearance: Liquid
- Color: Colorless to light yellow
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Medchemexpress LLC Benzyl acetate | 140-11-4 | 1 ML
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Benzyl acetate is an aromatic ester characterized by its jasmine scent. Found naturally in plants, this compound is widely utilized as a base fragrance ingredient in perfumes, cosmetics, and soap fragrances, and is a significant variety in the synthetic fragrance industry.
- Aromatic ester with a jasmine scent
- Found in plants
- Used as a base fragrance ingredient in perfumes, cosmetics, and soap fragrances
- Significant variety in the synthetic fragrance industry
- Purity of 99.94%
- Molecular weight of 150.18
- Chemical formula C9H10O2
- Appears as a liquid
- Colorless to light yellow
- Soluble in DMSO at 125 mg/mL
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Medchemexpress LLC 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- | 957205-14-0 | 98.0% | C10H21BrO5 | 1 G
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Bromo-PEG5-alcohol is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs work by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs utilize the ubiquitin-proteasome system
- Selectively degrades target proteins
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Aobchem AOBCHEM
5001000419 N- 3 5-DIMETHYLBENZYL -4-METHY
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Medchemexpress LLC 1-Benzyl-I3C | 60941-76-6 | 237.30 | 1 MG
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1-Benzyl-I3C is a NEDD4-1 inhibitor that exhibits significant anticancer activity. It directly inhibits the ubiquitination activity of NEDD4-1 with an IC50 of 12.3μM, which is significantly better than its precursor compound I3C (IC50 of 284μM). 1-Benzyl-I3C and its analogs have shown good effects in inhibiting the proliferation of human melanoma cells. In vitro ubiquitination experiments and thermal stability analysis indicate that 1-Benzyl-I3C binds to the catalytic HECT domain of NEDD4-1.
- Nedd4-1 inhibitor
- Significant anticancer activity
- Inhibits proliferation of human melanoma cells
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Aobchem AOBCHEM
5001003255 4- BENZYLOXY -5-FORMYL-2-METHO
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Medchemexpress LLC M-PEG24-alcohol | 2376450-73-4 | 99.7% | C49H100O25 | 250 MG
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m-PEG24-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins by utilizing two ligands connected by this linker: one for an E3 ubiquitin ligase and the other for the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates targeted protein degradation
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Medchemexpress LLC N-Boc-PEG5-alcohol | 1404111-67-6 | 97.0% | C15H31NO7 | 250 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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N-Boc-PEG5-alcohol is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Medchemexpress LLC Amino-PEG12-alcohol | 250MG
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Amino-PEG12-alcohol | 250MG
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Medchemexpress LLC Amino-PEG9-alcohol | 15332-95-3 | 98.0% | C18H39NO9 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Amino-PEG9-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by containing two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes the ubiquitin-proteasome system
- Facilitates selective degradation of target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem AOBCHEM
5001003086 2- 3-METHYLBENZYL PHENOL 1G
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Aobchem AOBCHEM
5001003085 2- BENZYLOXY -4-BROMO-1-CHLORO
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Aobchem AOBCHEM
5001003044 3- BENZYLOXY -2-BROMO-6-FLUOR
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Aobchem AOBCHEM
5001003161 3- BENZYLOXY -2-BROMO-6-FLUOR
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Aobchem AOBCHEM
5001000451 3- BENZYLOXY -2-BROMO-6-FLUOR
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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