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PS10 is a small-molecule, ATP-competitive pan-pyruvate dehydrogenase kinase (PDK) inhibitor used in research to probe metabolic pathways and cardiac metabolism. It has been reported to improve glucose tolerance and stimulate myocardial carbohydrate oxidation in diet-induced obesity models.
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Bromo-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Can be used in the synthesis of PROTACs
Contains two different ligands connected by a linker
One ligand for an E3 ubiquitin ligase
Other ligand for the target protein
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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Benzyl 2-bromoethyl ether is a biochemical reagent suitable for life science research as a biological material or organic compound. It can also be used in the synthesis of other active compounds.
Biochemical reagent
Used in life science research
Can be used for synthesizing active compounds
Drug intermediate
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2-Heptyl-4-quinolone is an intermediate in the synthesis of the Pseudomonas quinolone signal (PQS). It controls swarming by positively regulating phenazine production and induces the production of phenazine-1-carboxylic acid (PCA). This product is intended for research use only.
Controls swarming by positively regulating phenazine production
Induces the production of phenazine-1-carboxylic acid (PCA)
Appears as a solid
Light yellow to yellow color
Molecular weight: 243.34
Formula: C16H21NO
Classified as an alkaloid, specifically a quinoline alkaloid
Initially sourced from microorganisms, Pseudomonas aeruginosa
Storage (solid): Room temperature, protect from light
Storage (in solvent): -80°C for 1 year, -20°C for 6 months
Solubility (in vitro): 50 mg/mL in DMSO (205.47 mM); requires ultrasonication
Exhibits antiproliferative activity with an IC50 value of 35 μM in A2780 cell line
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THP-PEG1-alcohol is a THP-protected PEG-based linker with a primary alcohol functional group, intended for use in the synthesis of PROTACs and other linker-containing small molecules. The reagent provides a short, flexible spacer and a THP-protected hydroxyl handle that can be selectively deprotected in multistep synthetic sequences, facilitating modular assembly of bifunctional compounds.
Short PEG spacer suitable for compact linker design.
(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-cycloheptylacetic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications - CAS: 2304413-61-2 - MDL: No data - InChIKey: UGMXHKLJUFZORO-QFIPXVFZSA-N - Molecular Weight: 393.483 - Molecular Formula: C24H27NO4 - Purity: ≥95% - Container Type: 60 mL HDPE - Pack Size: 10 g - Net Weight: 10 g - Gross Weight: 25 g - Commodity Code: 29242970 - Country Of Origin: China - IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-cycloheptylacetic acid - SMILES: O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@@H](C4CCCCCC4)C(O)=O
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(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-cycloheptylacetic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications - CAS: 2349413-71-2 - MDL: No data - InChIKey: UGMXHKLJUFZORO-JOCHJYFZSA-N - Molecular Weight: 393.483 - Molecular Formula: C24H27NO4 - Purity: ≥95% - Container Type: 60 mL HDPE - Pack Size: 10 g - Net Weight: 10 g - Gross Weight: 25 g - Commodity Code: 29242970 - Country Of Origin: China - IUPAC: (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-cycloheptylacetic acid - SMILES: O=C([C@@H](C1CCCCCC1)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)O
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3-Chlorogentisyl alcohol is a small-molecule inhibitor of E. coli β-glucuronidase with reported antiproliferative activity. It is provided as a high-purity solid for biochemical and enzyme inhibition research.
Potent E. coli β-glucuronidase inhibitor (IC50 0.74 μM; Ki 0.58 μM).
Molecular formula C7H7ClO3; molecular weight 174.58 g/mol.
Purity 99.7%.
Available as solid quantities (including 10 mg) and as a 10 mM solution in DMSO.
Appearance off-white to light yellow solid.
Storage: powder -20°C; in solvent -80°C for 6 months, -20°C for 1 month.
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N-((Benzyloxy)carbonyl)-N-methyl-L-valine is a laboratory chemical used for the manufacture of substances. It is stable under recommended storage conditions and is intended for research use only. This product should be handled by suitably qualified and experienced scientists in appropriately equipped and authorized facilities.
Stable under recommended storage conditions
For research use only
Should be handled by qualified experienced scientists in appropriate facilities
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N-Pentanoyl 2-benzyltryptamine is a research compound that acts as a potent and selective antagonist of the MT2 melatonin receptor. It is used in receptor pharmacology to study MT2-mediated signaling and antagonist potency.
Potent MT2 antagonist (human MT2 pKi = 8.03).
High selectivity versus MT1 and mel1c receptors (~89-fold and ~229-fold).
High purity (99.0%).
Molecular formula C22H26N2O and molecular weight 334.45 g/mol.
Supplied in small-mass quantities suitable for in vitro research (5 mg-100 mg).
Useful for antagonist profiling and receptor signaling studies.
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2-(Benzyloxy)-1-ethanamine is an organic reagent supplied for research use as a liquid. It is used as an intermediate or building block in organic and medicinal chemistry, and for derivatization in life-science research. Analytical documentation is provided to support quality and safe handling.
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