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Filtered Search Results
Medchemexpress LLC Streptomycin sulfate | 3810-74-0 | MFCD00037023 | 98.4% | 1 ML
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Streptomycin sulfate is an aminoglycoside antibiotic that inhibits protein synthesis. It is intended for research use only.
- Inhibits protein synthesis.
- Available as a 10 mM in 1 mL solution for immediate use.
- High purity of 98.4%.
- Referenced in numerous scientific publications.
- Active against various bacterial strains.
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Medchemexpress LLC HY-15260A 100mg , XL413 (hydrochloride) CAS:1169562-71-3 Purity:98%
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Medchemexpress, HY-15260A 100mg XL413 (hydrochloride) CAS:1169562-71-3 Formula:C14H13Cl2N3O2 IC50: 3.4 nM (Cdc7), 42 nM (PIM1), 215 nM (CK2) EC50: 118 nM (pMCM) Purity:98% XL413 hydrochloride is a potent, selective and ATP competitive inhibitor of Cdc7 , with an IC 50 of 3.4 nM, and also shows potent effect with IC 50 s of 215, 42 nM on CK2, PIM1, respectively, and an EC 50 of 118 nM on pMCM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Erythromycin lactobionate | 3847-29-8 | MFCD00868832 | 100 MG
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Erythromycin lactobionate is a macrolide antibiotic produced by actinomycete *Streptomyces erythreus* with a broad spectrum of antimicrobial activity. It binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin lactobionate also exhibits antitumor and neuroprotective effects in different fields of research.
- Inhibits RNA-dependent protein synthesis
- Exhibits antitumor effects
- Provides neuroprotective benefits
- Inhibits growth of *P. falciparum*
- Shows antioxidant properties
- Reduces inflammation by suppressing 4-HNE and 8-OHdG, and reducing Iba-1 and TNF-a expression
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Medchemexpress LLC HY-19535A 5mg Medchemexpress, Nemiralisib CAS:1254036-71-9 Purity:>98%
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Medchemexpress, HY-19535A 5mg Nemiralisib CAS:1254036-71-9 Nemiralisib (GSK2269557 free base) is a potent and highly selective PI3Kδ inhibitor with a pKi of 9.9. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-17620 5mg Medchemexpress, Sacubitrilat CAS:149709-44-4 Purity:>98%
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Medchemexpress, HY-17620 5mg Sacubitrilat CAS:149709-44-4 Sacubitrilat is an active neprilysin (NEP) inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Dirithromycin | 62013-04-1 | 98.0% | 1 ML
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Dirithromycin is a potent, orally active, semi-synthetic macrolide antibiotic derived from Erythromycin. It demonstrates activity against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis. This product is intended for research use only.
- Semi-synthetic macrolide antibiotic
- Derived from Erythromycin
- Active against gram-positive bacteria
- Effective against *Legionella spp.*, *Helicobacter pylori*, and *Chlamydia trachomatis*
- Demonstrates potent *in vitro* activity against *Legionella* and *Helicobacter pylori*
- Effective in experimental infections caused by *S. aureus*, *S. pyogenes*, and *S. pneumoniae*
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Medchemexpress LLC Hygromycin B | 31282-04-9 | >99.9% | 10 G
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Hygromycin B, also known as Hygrovetine, is an aminoglycoside antibiotic effective against both prokaryotic and eukaryotic cells. It functions by strongly inhibiting 70S and 80S ribosomes, thereby preventing protein synthesis through ribosomal translocation. Synthesized by *Streptomyces hygroscopicus*, it is widely used in research applications, including resistance selection in transgenic models.
- Active against prokaryotic and eukaryotic cells
- Inhibits protein synthesis by blocking 70S and 80S ribosomes
- Prevents ribosomal translocation
- Used in resistance selection experiments
- Applicable in cell proliferation/viability assays
- Suitable for Western blot and immunofluorescence analyses
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Medchemexpress LLC Isoniazid-d4 | 774596-24-6 | 99.9% | 5 MG
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Isoniazid-d4 is the deuterium-labeled Isoniazid. Isoniazid (INH) is a proagent that requires activation by the bacterial catalase-peroxidase enzyme KatG. It is bactericidal to rapidly dividing mycobacteria and exhibits anti-tuberculostatic activity.
- Can be utilized as a tracer
- Can serve as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS
- Deuteration has potential to influence pharmacokinetic and metabolic profiles of drugs
- Suitable for research use only
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Medchemexpress LLC Ampicillin | 69-53-4 | 99.9% | 25 G
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Ampicillin is a broad-spectrum beta-lactam antibiotic effective against a variety of gram-positive and gram-negative bacteria. It has shown efficacy in various in vitro and in vivo studies.
- Inhibits the growth of E. coli
- Alleviates symptoms of hemorrhagic enteritis
- Produces high concentrations in bile
- Provides neuroprotection against ischemia-reperfusion brain injury
- Reduces matrix metalloproteinase (MMP) activities
- Increases glutamate transporter 1 (GLT-1) expression
- Reduces medial hippocampal cell death after global forebrain ischemia
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Medchemexpress LLC Spectinomycin dihydrochloride | 21736-83-4 | 99.73% | 25 G
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Spectinomycin dihydrochloride is a broad-spectrum antibiotic that inhibits the growth of various gram-positive and gram-negative organisms. It functions by selectively targeting bacterial ribosomes and interrupting protein synthesis, and acts as a noncompetitive inhibitor of td intron RNA with a Ki value of 7.2 mM.
- Broad-spectrum antibiotic
- Inhibits growth of gram-positive and gram-negative organisms
- Selectively targets bacterial ribosomes
- Interrupts protein synthesis
- Acts as a noncompetitive inhibitor of td intron RNA
- Inhibits polypeptide synthesis
- Blocks translocation of peptidyl-tRNAs
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Medchemexpress LLC Nateglinide-d5 | 1227666-13-8 | 98.0% | 1 MG
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Nateglinide-d5 is a deuterium labeled Nateglinide. Nateglinide, a D-phenylalanine derivative, is an orally active and short-acting insulinotropic agent and a DPP IV inhibitor. It inhibits ATP-sensitive K+ channels in pancreatic β-cells and is used for the treatment of type 2 (non-insulin-dependent) diabetes mellitus.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Medchemexpress LLC Isonicotinic acid hydrazide-d4 | 774596-24-6 | 99.9% | 1 MG
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Isoniazid-d4 is a deuterium-labeled form of Isoniazid, a proagent activated by the bacterial catalase-peroxidase enzyme KatG. It exhibits bactericidal activity against rapidly dividing mycobacteria and possesses anti-tuberculostatic properties.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes for quantitation during drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
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Medchemexpress LLC Neomycin (sulfate) (Standard) | 1405-10-3 | 99.9% | 1 G
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Neomycin sulfate is an aminoglycoside antibiotic that functions by irreversibly binding to the nuclear 30S ribosomal subunit, which blocks bacterial protein synthesis. It is utilized in cancer research and has various biochemical inhibitory actions.
- Acts as a phospholipase C (PLC) inhibitor.
- Inhibits the nuclear translocation of angiogenin and its associated cell proliferation and angiogenesis.
- Can inhibit IP3-mediated Ca2+ release.
- Can inhibit MgATP-dependent Ca2+ uptake.
- Can inhibit electrical excitation-evoked skeletal muscle Ca2+ transients.
- Prolonged exposure can deplete gut microbiota in specific mouse models.
- May cause hearing impairment and kidney damage with prolonged exposure.
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Medchemexpress LLC Erythromycin (thiocyanate) | 7704-67-8 | 96.4% | 1 G
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Erythromycin thiocyanate is a macrolide antibiotic produced by *Streptomyces erythreus*, known for its broad-spectrum antimicrobial activity. It functions by inhibiting bacterial 50S ribosomal subunits, thereby blocking RNA-dependent protein synthesis. This compound also exhibits antitumor and neuroprotective effects.
- Inhibits RNA-dependent protein synthesis
- Broad-spectrum antimicrobial activity
- Antitumor effects
- Neuroprotective effects
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Medchemexpress LLC HY-50769 50mg Medchemexpress, VTP-27999 (TFA) CAS:1013937-63-7 Purity:>98%
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Medchemexpress, HY-50769 50mg VTP-27999 (TFA) CAS:1013937-63-7 VTP-27999 TFA is an alkyl amine Renin inhibitor; VTP-27999 TFA is useful for Hypertension and End-Organ Diseases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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