Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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2,026 – 2,040 of 7,041 results

2,026

Medchemexpress LLC Ruxolitinib (S enantiomer) | 941685-37-6 | MFCD13184797 | 99.9% | 306.37 | C17H18N6 | 10 MG

Ruxolitinib (S enantiomer) is the single S enantiomer of ruxolitinib, an orally active and potent Janus kinase (JAK) inhibitor used in preclinical research to probe JAK-dependent signaling and related disease models. It has demonstrated in vitro suppression of interferon-β-induced gene expression and in vivo activity in myeloproliferative neoplasm models.

Orally active, potent JAK inhibitor.
Suitable for in vitro and in vivo preclinical studies.
Chemical formula C17H18N6, molecular weight 306.37.
CAS number 941685-37-6.
Reported purity 99.9%.
Available as solid and solution formats, including 10 mg solid and 10 mM in DMSO.

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2,027

Medchemexpress LLC 2-[[2,6-dichloro-4-(3,5-dimethyl-4-isoxazolyl)phenyl]amino]-benzoic acid | 2243736-35-6 | MFCD32669807 | >98.0% | C18H14Cl2N2O3 | 10MG

FB23 is a potent, selective small-molecule inhibitor of the fat mass and obesity-associated (FTO) mRNA N6-methyladenosine (m6A) demethylase. It binds directly to FTO and inhibits its demethylase activity (IC50 ~60 nM), and has been used in cellular studies to probe FTO function and effects on leukemia cell proliferation.

Potent FTO inhibition (IC50 ~60 nM).
Selective for FTO over related demethylases.
Direct binding to the target demonstrated.
Suitable for cellular assays probing m6A regulation and proliferation effects.
Supplied as a solid with high purity (>98%).

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2,028

AdipoGen FK-506,Chemical. CAS: 109581-93-3

FK-506, AdipoGen Life Sciences. Chemical. CAS: 109581-93-3. Formula: C44H69NO12 . H2O. MW: 804.0 . 18.0. Isolated from Streptomyces FCZ0311. Potent immunosuppressant (as cyclosporin A and rapamycin). Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Forms a complex with FK-506 binding protein 12 (FKBP12). Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B (PP2B; calcineurin), leading to disruption of T cell activation. Prevents rejection of transplanted organs. Anti-inflammatory compound in the treatment of several inflammatory skin diseases (e.g. atopic dermatitis) and with potential anti-rheumatic activity (rheumatoid arthritis). Neuroprotective. Regulates nitric oxide neurotoxicity. Neurotransmitter. Ca2+ release compound. NF-kappaB suppressor by induction of unfolded protein response (UPR). Anti-cancer compound. Apoptosis inducer.

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2,029

Medchemexpress LLC HY-101189 5mg Medchemexpress, JNJ-39758979 CAS:1046447-90-8 Purity:>98%

Medchemexpress, HY-101189 5mg JNJ-39758979 CAS:1046447-90-8 JNJ-39758979 is a selective, high-affinity histamine H 4 receptor antagonist with a K i of 12.5 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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2,030

eMolecules Amd 3100 octahydrochloride | 155148-31-5 | MFCD04974488 | 1g

Combi-Blocks, Inc. | Amd 3100 octahydrochloride | 1g | 586078722 | QV-3465 | 95.000 | 155148-31-5 | MFCD04974488 | 794.460 | C28H62Cl8N8

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
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2,031

Medchemexpress LLC HY-11005 5mg Medchemexpress, BX-912 CAS:702674-56-4 Purity:>98%

Medchemexpress, HY-11005 5mg BX-912 CAS:702674-56-4 BX-912 is a direct, selective, and ATP-competitive PDK1 inhibitor (IC50=26 nM). BX-912 blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines in culture or induces apoptosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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2,032

eMolecules 162359-55-9 | 2-Amino-2-(4-octylphenethyl)propane-1,3-diol | Combi-Blocks | MFCD14705150 | 307.478 | C19H33NO2 | 97.000 | CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1 | 1g | 485191502

2-Amino-2-(4-octylphenethyl)propane-1,3-diol | Combi-Blocks | 162359-55-9 | MFCD14705150 | 307.478 | C19H33NO2 | 97.000 | CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1 | 1g | 485191502

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2,033

Apexbio Technology LLC CCT007093 176957-55-4 10mg

CCT007093 (CAS 176957-55-4) is a small-molecule inhibitor targeting PPM1D a protein phosphatase involved in cellular stress response pathways It is a thienylidene cyclopentanone derivative that exhibits inhibitory activity against PPM1D with an IC50 of 8 4 M in vitro using recombinant phosphorylated p38 as a substrate In cellular assays CCT007093 selectively reduces viability in MCF-7 cells compared to HeLa cells decreasing cell viability by 40% after two days The compound induces cell death in a p38 kinase-dependent manner and increases p38 phosphorylation an effect reversible by the p38 inhibitor SB203580 CCT007093 is used in research on PPM1D function and in studies of stress signaling and targeted cell death

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2,034

Medchemexpress LLC HY-10373 5mg , Trimetrexate CAS:52128-35-5 Purity:>98%

HY-10373 5mg Trimetrexate CAS: 52128-35-5 Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer[4][5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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2,035

Medchemexpress LLC Duocarmycin analog | 372954-15-9 | 95.9% | 611.09 g·mol⁻¹ | C34H31ClN4O5 | 1 MG

Duocarmycin analog is a synthetic analog of duocarmycin used as a DNA alkylator and as an antibody-drug conjugate (ADC) payload for research applications. Supplied as a solid powder, it is intended for laboratory research use only and not for human or clinical use.

Acts as a DNA alkylator and ADC cytotoxin.
Available sizes: 1 mg, 5 mg, 10 mg.
Purity: 95.9%.
Cas number: 372954-15-9.
Molecular formula: C34H31ClN4O5; molecular weight: 611.09 g·mol⁻¹.
Storage: powder -20°C (up to 3 years); in solvent -80°C for 6 months, -20°C for 1 month.
Appearance: off-white to light yellow solid.

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2,036

Medchemexpress LLC MC-Val-Cit-PAB-duocarmycin chloride | 2055896-98-3 | 99.0% | 1055.05 | C54H65Cl2N9O9 | 10 MG

MC-Val-Cit-PAB-duocarmycin chloride is an antibody-drug conjugate (ADC) agent-linker conjugate that links a valine-citrulline cleavable linker and para-aminobenzyl (PAB) spacer to a duocarmycin payload for use in ADC research. It is supplied as a solid, high-purity compound intended for evaluating linker-payload performance and cytotoxic activity in preclinical studies.

Cleavable valine-citrulline linker with para-aminobenzyl spacer.
Duocarmycin payload that binds the DNA minor groove and alkylates DNA.
High purity (99.0%) solid suitable for research applications.
Supplied as a 10 MG quantity.
Store at -80°C, protect from light; unstable in solution.

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2,037

Medchemexpress LLC Azithromycin hydrate | 117772-70-0 | 785.02 | 5 MG

Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.

Useful for bacterial infections.
Augments rhinovirus-induced IFNβ expression.
Specifically reduces MMP-9 mRNA and protein levels.
No effect on bronchoalveolar lavage inflammatory parameters in mouse model of asthma exacerbation.
Augments expression of interferon-stimulated genes and pattern recognition receptor MDA5.

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2,038

Research Products International Corp Nalidixic Acid, 25 Grams

Nalidixic Acid Sodium Salt is a chemical compound that is used for its antimicrobial properties and has various applications in microbiology, and pharmaceutical research. Nalidixic Acid Sodium Salt is employed as a reference standard and selective agent in microbiological culture media. It inhibits the growth of susceptible bacteria, making it a valuable tool for studying bacterial susceptibility and resistance patterns.

Researchers use it to assess the effectiveness of antibiotics against different bacterial strains, contributing to our understanding of microbial biology and antibiotic resistance.

WARNING! This product can expose you to Nalidixic acid, a chemical which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

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2,039

Medchemexpress LLC 4-amino-N-[3-methyl-1-[(6-methyl-2-pyridinyl)methyl]indazol-4-yl]thienopyrimidine-7-carboxamide | 1527517-50-5 | 98.6% | 429.5 g/mol | C22H19N7OS | 25MG

c-Fms-IN-10 is a thieno[3,2-d]pyrimidine-derived small-molecule inhibitor of the receptor tyrosine kinase c-Fms (colony-stimulating factor-1 receptor, CSF-1R). It exhibits potent inhibitory activity against CSF-1R (reported IC50 = 2 nM), has demonstrated anti-tumor activity in preclinical studies, and is supplied as a high-purity solid or as a 10 mM solution in DMSO for biochemical and cellular research applications.

Molecular formula: C22H19N7OS.
Molecular weight: 429.5 g/mol.
Purity: 98.6% (as listed).
Reported potency: CSF-1R IC50 = 2 nM.
Available as powder and as a 10 mM solution in DMSO.
Intended for research use only; not for human or clinical use.

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2,040

Medchemexpress LLC Xanomeline | 131986-45-3 | MFCD00867179 | 99.95% | 281.42 g·mol⁻¹ | C14H23N3OS | 10 MG

Xanomeline is a selective muscarinic M1/M4 receptor agonist used as a research reagent in neuroscience to investigate cholinergic signaling and neuropsychiatric disorders. It is provided as a high-purity chemical for laboratory use; consult the product data sheet and safety data sheet for handling, storage, and experimental guidance.

Selective muscarinic M1/M4 receptor agonist.
High purity suitable for analytical and biological research.
Available in multiple small-scale quantities for laboratory use.
Supplied with a product data sheet and a safety data sheet.
Used to study cholinergic signaling and neuropsychiatric disease models.
Compatible with in vitro and in vivo experimental protocols.

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Antibiotics

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Medchemexpress LLC Ruxolitinib (S enantiomer) | 941685-37-6 | MFCD13184797 | 99.9% | 306.37 | C17H18N6 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-[[2,6-dichloro-4-(3,5-dimethyl-4-isoxazolyl)phenyl]amino]-benzoic acid | 2243736-35-6 | MFCD32669807 | >98.0% | C18H14Cl2N2O3 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-101189 5mg Medchemexpress, JNJ-39758979 CAS:1046447-90-8 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-11005 5mg Medchemexpress, BX-912 CAS:702674-56-4 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-10373 5mg , Trimetrexate CAS:52128-35-5 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Duocarmycin analog | 372954-15-9 | 95.9% | 611.09 g·mol⁻¹ | C34H31ClN4O5 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MC-Val-Cit-PAB-duocarmycin chloride | 2055896-98-3 | 99.0% | 1055.05 | C54H65Cl2N9O9 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azithromycin hydrate | 117772-70-0 | 785.02 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Nalidixic Acid, 25 Grams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4-amino-N-[3-methyl-1-[(6-methyl-2-pyridinyl)methyl]indazol-4-yl]thienopyrimidine-7-carboxamide | 1527517-50-5 | 98.6% | 429.5 g/mol | C22H19N7OS | 25MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Xanomeline | 131986-45-3 | MFCD00867179 | 99.95% | 281.42 g·mol⁻¹ | C14H23N3OS | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More