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Filtered Search Results
eMolecules 329907-28-0 | Medchem Express | TTP 22 | 10mg | 446265774 | HY-15479 | MFCD02654497 | 330.42 | C16H14N2O2S2
Medchem Express | L-Glutamine-15N | 5mg | 721611324 | HY-N0390S | 80143-57-3 | MFCD00084215 | 147.139 | C5H10N2O3
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Medchemexpress LLC Pritelivir mesylate | 1428333-96-3 | C19H22N4O6S3 | 5 MG
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Pritelivir mesylate is an inhibitor of the viral helicase-primase complex, demonstrating antiviral activity both in vitro and in animal models of herpes simplex virus (HSV) infection. It is effective against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with an IC50 of 0.02 μM. As the first in its class of antiviral agents, it inhibits HSV replication by targeting the viral helicase-primase enzyme complex.
- Inhibits the viral helicase-primase complex.
- Active against herpes simplex virus types 1 and 2.
- Effective with an IC50 of 0.02 μM against HSV1-2.
- Significantly increases survival and reduces mortality against HSV-1 and HSV-2 in animal models.
- Exhibits potent and resistance-breaking antiviral efficacy.
- Potential treatment for life-threatening HSV infections.
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AG Scientific Inc Ampicillin, Sodium Salt, 5 G
Ampicillin Sodium Salt is a Beta-Lactam antibiotic within the penicillin family. It inhibits synthesis of bacterial cell wall by inactivation of transpeptidases. It is used as a selective agent of ampicillin resistance in mutated and transformed cells having plasmid encoding for Beta-Lactamase production such as pBR322 or pUC.It is sensitive to Beta-lactamase, which hydrolyzes Beta-lactam ring. This antibiotic is effective against gram positive and highly effective against gram negative bacteria.CAS Number: 69-52-3Molecular Weight: 371.4 DaChemical Formula: C16H18N3O4S NaSolubility: Soluble in waterStorage Temperature: +4CResearch or further manufacturing use only, not for food or drug use.
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AG Scientific Inc Carbenicillin Disodium,5G
Carbenicillin Disodium Salt is a penicillin-derived Beta-lactam antibiotic that interferes with cell wall synthesis, primarily in gram-negative bacteria such as Pseudomonas aeruginosa, while showing low toxicity to plant tissues. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal area by opening the lactam ring. This inactivation intercepts the cross-linkage of peptidoglycan strands, by impeding the third and last phase of bacterial cell wall synthesis. This prompts inadequate bacterial cell wall synthesis and causes cell lysis.CAS Number: 4800-94-6Molecular Weight: 422.4Chemical Formula: C17H16N2O6SNa2Solubility: Soluble in water: clear and slightly yellow solution at 50 mg/mLStorage Temperature: +4CResearch or further manufacturing use only, not for food or drug use.
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Apexbio Technology LLC Tylosin phosphate 1405-53-4 50mg
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Tylosin phosphate (CAS 1405-53-4) is a small-molecule inhibitor targeting bacterial ribosomal subunits It is designed to interfere with bacterial translation thereby inhibiting bacterial protein synthesis Tylosin phosphate exerts its biological activity primarily through binding to ribosomal subunits of Gram-positive bacteria In in vitro studies tylosin phosphate demonstrates inhibitory activity with reported IC50 values generally ranging between 0 5 5 g/mL depending on bacterial strain and assay conditions Based on these pharmacological properties tylosin phosphate holds research potential in studies of antibiotic resistance mechanisms antibacterial spectrum evaluation and as an antibiotic additive to explore growth promotion and therapeutic utility in poultry swine and bovine models
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Apexbio Technology LLC Amoxicillin Sodium 34642-77-8 1g
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Amoxicillin Sodium (CAS 34642-77-8) is a small-molecule inhibitor targeting bacterial cell wall biosynthesis It is designed to disrupt peptidoglycan formation thereby compromising bacterial cell wall integrity Amoxicillin Sodium exerts its biological activity primarily through inhibition of peptidoglycan biosynthesis leading to bacterial lysis and cell death In in vitro studies Amoxicillin Sodium demonstrates broad-spectrum antibacterial inhibitory activity with IC50 values ranging from 0 1 g/mL to 10 g/mL depending on bacterial strain variability and experimental conditions Based on these pharmacological properties Amoxicillin Sodium holds research potential in bacterial physiology characterization antibiotic resistance evaluations and in vitro infection modeling studies
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Apexbio Technology LLC Perphenazine 58-39-9 1g
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Perphenazine (CAS 58-39-9) is a phenothiazine derivative that primarily acts as an antagonist at dopamine D receptors with dissociation constant (Ki) of 1 4 nM and also displays significant binding to histamine H (Ki 8 nM) A-adrenergic (Ki 10 nM) A- B- C-adrenergic and muscarinic M (Ki 1848 nM) receptors Its antagonism at D receptors underlies its ability to modulate dopaminergic neurotransmission while interaction with additional receptor subtypes may account for its effects on the central nervous system and antiemetic properties Perphenazine is widely utilized in research investigating mechanisms of antipsychotic activity dopaminergic regulation and drug-induced cell death pathways
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377486 R -MORINIDAZOLE 100MG
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Waters Corp UPC2 Standard Ibuprofen 186006521
Individual ibuprofen standard formulated for use with SFC. 1.0 mg/mL ibuprofen in 2-propanol, 2mL
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Apexbio Technology LLC Isoconazole nitrate 24168-96-5 50mg
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Isoconazole nitrate (24168-96-5) is a small-molecule inhibitor targeting ergosterol biosynthesis It is designed to inhibit the synthesis of ergosterol a key structural component of fungal cell membranes thereby compromising membrane integrity and biological function Isoconazole nitrate exerts its biological activity primarily through inhibition of ergosterol synthesis In in vitro studies isoconazole nitrate demonstrates antifungal activity by disrupting fungal cell viability and proliferation and also exhibits activity against certain gram-positive bacterial strains Based on these pharmacological properties isoconazole nitrate holds research potential in evaluating antifungal activity (such as MIC or IC50 values) investigating mechanism-related effects and exploring pharmacokinetics tissue distribution and therapeutic efficacy in experimental models of fungal or bacterial infection
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Apexbio Technology LLC Tolvaptan 150683-30-0 5mg
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Tolvaptan (CAS 150683-30-0) is a selective orally active antagonist of the arginine vasopressin (AVP) V2 receptor In binding assays using HeLa cells expressing human AVP receptor subtypes tolvaptan exhibits high affinity for the V2 receptor (Ki 0 43 nM) and substantially lower affinity for the V1a receptor (Ki 12 3 nM) with minimal activity at V1B and other off-target receptors or ion channels Tolvaptan inhibits AVP-induced cAMP accumulation with an IC50 of 8 nM In animal models administration of tolvaptan increases urine output and serum sodium and elevates plasma sodium while reducing mortality in hyponatremic rats This compound is widely utilized in research exploring water balance AVP signaling and hyponatremia mechanisms
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Medchemexpress LLC HY-113098 5mg Medchemexpress, 2-Oxovaleric acid CAS:1821-02-9 Purity:>98%
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Medchemexpress, HY-113098 5mg 2-Oxovaleric acid CAS:1821-02-9 2-Oxovaleric acid is a keto acid that is found in human blood. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-117632 10mg Medchemexpress, ABX-1431 CAS:1446817-84-0 Purity:>98%
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Medchemexpress, HY-117632 10mg ABX-1431 CAS:1446817-84-0 ABX-1431 is a highly potent, selective, and orally available, CNS-penetrant monoacylglycerol lipase ( MAGL ) inhibitor with an IC 50 of 14 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380942 HS-243 100MG
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Apexbio Technology LLC FR 180204 865362-74-9 10mg
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FR 180204 (CAS 865362-74-9) is a small-molecule inhibitor targeting extracellular signal-regulated kinase (ERK) specifically ERK1 and ERK2 It modulates ERK activity thereby regulating MAP kinase signaling pathways FR 180204 exerts its biological activity primarily through ATP-competitive inhibition of ERK1 and ERK2 In in vitro studies FR 180204 demonstrates selective inhibition of ERK1 and ERK2 with IC50 values of 0 31 M and 0 14 M respectively and limited inhibition of related kinases In cell-based assays using Mv1Lu cells it inhibits TGF -induced AP-1 transcriptional activation with an IC50 of approximately 3 1 M Based on these pharmacological properties FR 180204 holds research potential in elucidating ERK-mediated signaling and transcriptional regulation in biomedical studies
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