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Filtered Search Results
Medchemexpress LLC HY-112629 10mg Medchemexpress, PDM2 CAS:688348-25-6 Purity:>98%
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Medchemexpress, HY-112629 10mg PDM2 CAS:688348-25-6 PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Undecanoic acid >=99%, FG | 112-37-8 | MFCD00002730 | 100G
Undecanoic acid >=99%, FG | Purity: >=99% | Mol Wt: 186.29 | 112-37-8 | MFCD00002730 | 100G
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Medchemexpress LLC HY-15510B 5mg Medchemexpress, Tenovin-6 (Hydrochloride) CAS:1011301-29-3 Purity:>98%
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Medchemexpress, HY-15510B 5mg Tenovin-6 (Hydrochloride) CAS:1011301-29-3 Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH)[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Research Products International Corp Amoxicillin Trihydrate, 25 Grams
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Amoxicillin is a broad-spectrum, semi-synthetic penicillin antibiotic that is effective against a wide range of bacteria. The trihydrate form of amoxicillin is a crystalline powder that is often used in laboratory settings.
Amoxicillin inhibits the growth of bacteria by interfering with their cell wall synthesis. It is a versatile antibiotic with low toxicity to mammalian cells, making it a valuable tool in maintaining sterile conditions in cell cultures and studying bacterial physiology.
Researchers use amoxicillin to selectively culture bacteria or to treat bacterial infections in cell cultures.
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Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 2 MG
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Ipatasertib dihydrochloride is a highly selective, ATP-competitive pan-Akt inhibitor targeting Akt1, Akt2, and Akt3 with IC50s of 5, 18, and 8 nM, respectively. This compound demonstrates significant selectivity for Akt1 over PKA (more than 600-fold) and p70S6K (over 100-fold). In broader kinase profiling, it inhibits only PRKG1α, PRKG1β, and p70S6K by more than 70% at 1 μM concentration.
- Highly selective, ATP-competitive pan-Akt inhibitor
- Inhibits Akt1, Akt2, and Akt3 with high potency
- Demonstrates significant selectivity for Akt1 over PKA and p70S6K
- Inhibits PRKG1α, PRKG1β, and p70S6K at 1 μM
- Intended for research use only
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Medchemexpress LLC HY-13441 10mg Medchemexpress, (-)-Blebbistatin CAS:856925-71-8 Purity:>98%
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Medchemexpress, HY-13441 10mg (-)-Blebbistatin CAS:856925-71-8 (-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-13613 10mg Medchemexpress, Dutasteride CAS:164656-23-9 Purity:>98%
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Medchemexpress, HY-13613 10mg Dutasteride CAS:164656-23-9 Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Streptomycin | 57-92-1 | 99.91% | 100 MG
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Streptomycin is a potent antibiotic effective against *M. tuberculosis* for tuberculosis (TB) research and various bacterial infections. It functions by strongly binding to nucleic acids, which interferes with and blocks protein synthesis while allowing continued RNA and DNA synthesis. This compound is also commonly used as an antibiotic in culture media and acts as a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes.
- Effective antibiotic against *M. tuberculosis*.
- Used for tuberculosis (TB) research.
- Bactericidal agent for various bacterial infections.
- Interferes with and blocks protein synthesis.
- Permits continued RNA and DNA synthesis.
- Commonly used antibiotic in culture media.
- Blocks stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes.
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Medchemexpress LLC (E)-N-((Z)-4-benzyl-3-methyl-1,2,4-thiadiazol-5(4H)-ylidene)-N'-phenylbenzimidamide | 324579-65-9 | 99.9% | 384.50 g/mol | C23H20N4S | 10MG
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RNF5 inhibitor inh-02 is a small-molecule inhibitor of the E3 ubiquitin ligase RNF5 (RMA1) that reduces ATG4B ubiquitylation, increases LC3IIB expression and autophagic vacuole number, and rescues F508del-CFTR function in cellular models (reported EC50 ≈ 2.2-2.6 μM). It is supplied as a solid or DMSO solution for research use in cellular assays and mechanistic studies.
- High purity (99.91%).
- Molecular formula C23H20N4S and molecular weight 384.50 g/mol.
- Demonstrated cellular activity rescuing F508del-CFTR (EC50 ≈ 2.2-2.6 μM).
- Soluble in DMSO (~83.33 mg/mL); ultrasonic heating to 60°C recommended for dissolution.
- Available as solid and as prepared DMSO solution formats for convenience.
- Suitable for research into RNF5 biology and cystic fibrosis-related cellular models.
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Medchemexpress LLC HY-B2174 100mg Medchemexpress, Ethacridine (lactate) CAS:1837-57-6 Purity:>98%
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Medchemexpress, HY-B2174 100mg Ethacridine (lactate) CAS:1837-57-6 Ethacridine lactate is a poly(ADP-ribose) glycohydrolase ( PARG ) inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Spiramycin I | 24916-50-5 | 50 MG
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Spiramycin I is a macrolide antibiotic and antiparasitic intended for research use only. It functions by binding to the 50S subunit of the ribosome, which blocks the synthesis of peptide chains.
- Acts as a macrolide antibiotic and antiparasitic
- Exhibits inhibitory activity against Gram-positive bacteria, including B. subtilis, M. luteus, S. aureus, S. epidermidis, and S. pneumoniae with MICs ranging from 0.5-8 μg/mL
- Shows cytotoxicity in cancer cells such as HeLa, KB, MCF-7, HepG2, and U87, with IC50 values between 30.51 and 34.41 μM
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Medchemexpress LLC Bemnifosbuvir | 1998705-64-8 | 99.0% | 581.53 | 50 MG
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Bemnifosbuvir (AT-511) is a potent and orally active inhibitor of HCV viral replication. It is highly effective in controlling SARS-CoV-2 (COVID-19) infection in vitro with an EC90 of 0.47 μM. Bemnifosbuvir exhibits pangenotypic antiviral activity.
- Highly effective in controlling SARS-CoV-2 (COVID-19) infection in vitro
- Exhibits pangenotypic antiviral activity
- Inhibits HCV genotype 1a (EC50: 12.8 nM)
- Inhibits HCV GT1b (EC50: 12.5 nM)
- Inhibits HCV GT2a (EC50: 9.2 nM)
- Inhibits HCV GT3a (EC50: 10.3 nM)
- Inhibits HCV GT4a (EC50: 14.7 nM)
- Inhibits HCV GT5a (EC50: 28.5 nM)
- Preferentially delivers high levels of AT-9010 to the liver in vivo
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Cayman Chemical AzIthromycIn-13C-d3 500ug
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An internal standard for the quantification of azithromycin by GC- or LC-MS
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Apexbio Technology LLC PD173955 260415-63-2 5mg
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PD173955 (CAS 260415-63-2) is a small-molecule inhibitor targeting Bcr-Abl Src and Yes tyrosine kinases with reported IC50 values of 1 2 nM 300 nM and 175 nM respectively Bcr-Abl is associated with oncogenic transformation while Src and Yes are implicated in tumor cell survival proliferation and invasion In cellular assays PD173955 inhibits KL-dependent proliferation of CML CD34 progenitor cells (IC50 50 nM) and reduces G2-M phase cell populations accompanied by an increase in G1 phase cells In HT29 and Bcr-Abl-dependent cell lines PD173955 suppresses proliferation and Src autophosphorylation This compound is widely used in studies investigating kinase signaling and cell cycle regulation in cancer research
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Medchemexpress LLC 1-cyano-3-(4-cyanophenyl)-2-[(2R)-3,3-dimethylbutan-2-yl]guanidine | 220641-11-2 | MFCD30747839 | 99.6% | 269.34 g/mol | C15H19N5 | 50 MG
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Naminidil is a cyanoguanidine small molecule that acts as an ATP-sensitive potassium (KATP) channel opener. It is provided as a research-grade reagent for in vitro and in vivo pharmacological studies of potassium channel function and cardiovascular mechanisms. The compound has molecular formula C15H19N5, molecular weight 269.34 g/mol, and reported CAS number 220641-11-2.
- Acts as an ATP-sensitive potassium (KATP) channel opener for functional studies.
- High purity (about 99.6%) suitable for research applications.
- Available in multiple pack sizes including 50 mg for flexible dosing.
- Characterized molecular properties (C15H19N5; MW 269.34 g/mol).
- Provided with analytical documentation such as COA and SDS for safety and quality assurance.
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