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Filtered Search Results
Medchemexpress LLC BiP inducer X | 101714-41-4 | 99.6% | 209.22 | 100 MG
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BiP inducer X | 101714-41-4 | 99.6% | 209.22 | 100 MG
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Sigma Aldrich Fine Chemicals Biosciences Amphotericin B from Strept1G
Chemical structure polyene
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U.S. Pharmacopeia Vancomycin Hydrochloride, 1404-93-9, MFCD03613611, 500mg
Molecular formula C66H75Cl2N9O24 . HCl, Molecular weight 1485.71 g/mol, Synonyms: Vancomycin, monohydrochloride
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Apexbio Technology LLC Neomycin sulfate(Synonyms: Neomycin sulphate, Fradiomycin sulfate, Neomycin trisulfate salt hydrate, Neosulf), 10g, CAS: 1405-10-3.
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Neomycin sulfate (CAS 1405-10-3) is an aminoglycoside antibiotic that interacts with nucleic acid structures and ion channels influencing several biological processes It inhibits hammerhead ribozyme cleavage reactions by preferentially stabilizing the ribozyme-substrate ground-state complex thereby impeding catalytic turnover In HIV-1 research neomycin disrupts the interaction between Tat protein and the viral RNA TAR element via an allosteric noncompetitive mechanism Additionally neomycin binds specifically to DNA triplex structures particularly stabilizing TAT triplets It also demonstrates voltage- and concentration-dependent blockage of ryanodine receptor channels mainly from the luminal side These properties make neomycin sulfate valuable for mechanistic studies involving RNA/DNA structure interactions and channel functions
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Medchemexpress LLC Pptn hydrochloride | 1992047-65-0 | 99.89% | 511.96 | 10 MG
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PPTN hydrochloride is a potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. It shows no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. It also exhibits anti-inflammatory and anti-immune activity.
- Potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist
- Exhibits no agonist or antagonist effect at P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors
- Inhibits UDP-glucose-promoted chemotaxis in differentiated HL-60 human promyelocytic leukemia cells with IC50s of ~1 nM (in the presence of 10 μM UDP-glucose) and ~4 nM (in the presence of 100 μM)
- Significantly decreases the ratios of p-ERK1/2 to ERK1/2 and p-p38 to p38 at 10 μM
- Anti-inflammatory activity
- Anti-immune activity
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Medchemexpress LLC (3S,4S)-PF-06459988 | 1858291-14-1 | 98.97% | 431.88 | 50 MG
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(3S, 4S)-PF-06459988 is the S enantiomer of PF-06459988 with less activity. PF-06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). It exhibits excellent selectivity against EGFR wild-type, possessing a minimally reactive electrophile that reduces the propensity of off-target labeling.
- Potent irreversible inhibitor of T790M mutant EGFR.
- Excellent selectivity against EGFR wild-type.
- Minimally reactive electrophile to reduce off-target labeling.
- For research use only.
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Medchemexpress LLC Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-16-methyl-, (16β)- | 1247-42-3 | 99.6% | 50 MG
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Meprednisone is a glucocorticoid and a methylated derivative of Prednisone. It modulates glucocorticoid receptors and is orally active.
- Modulates glucocorticoid receptors
- Orally active
- Suitable for inflammation/immunology research
- Appears as a white to off-white solid
- High purity of 99.6%
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Research Products International Corp Carbenicillin, Disodium Salt, 25 Grams
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Carbenicillin, Disodium Salt is a semi-synthetic penicillin antibiotic effective against Gram-positive and Gram-negative bacteria. It is commonly used in molecular biology, genetic engineering, microbiology, and cell culture as a selective agent in plasmid-based cloning. It inhibits bacterial cell wall synthesis, allowing selection of cells expressing Carbenicillin resistance genes. This antibiotic prevents bacterial contamination in cell cultures and supports isolation and maintenance of resistant strains. Key features include broad-spectrum activity and stability in aqueous solutions.
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Research Products International Corp Chloramphenicol, 100 Grams
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Chloramphenicol is a phenicol-class antibiotic effective against a broad range of Gram-positive and Gram-negative bacteria. Commonly used in microbiology, cell culture, molecular biology, and genetic engineering, it serves as a selective agent by inhibiting bacterial protein synthesis via the 50S ribosomal subunit. It allows the growth of cells carrying the Chloramphenicol resistance gene while inhibiting non-transformed cells. It is used to maintain plasmids and vectors with the resistance gene and supports studies on gene expression and protein synthesis.
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Research Products International Corp Chloramphenicol, 25 Grams
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Chloramphenicol is a phenicol-class antibiotic effective against a broad range of Gram-positive and Gram-negative bacteria. Commonly used in microbiology, cell culture, molecular biology, and genetic engineering, it serves as a selective agent by inhibiting bacterial protein synthesis via the 50S ribosomal subunit. It allows the growth of cells carrying the Chloramphenicol resistance gene while inhibiting non-transformed cells. It is used to maintain plasmids and vectors with the resistance gene and supports studies on gene expression and protein synthesis.
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Research Products International Corp Carbenicillin, Disodium Salt, 5 Grams
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Carbenicillin, Disodium Salt is a semi-synthetic penicillin antibiotic effective against Gram-positive and Gram-negative bacteria. It is commonly used in molecular biology, genetic engineering, microbiology, and cell culture as a selective agent in plasmid-based cloning. It inhibits bacterial cell wall synthesis, allowing selection of cells expressing Carbenicillin resistance genes. This antibiotic prevents bacterial contamination in cell cultures and supports isolation and maintenance of resistant strains. Key features include broad-spectrum activity and stability in aqueous solutions.
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Medchemexpress LLC Wyc-210 | 2131803-93-3 | 99.2% | 340.40 | 50 MG
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WYC-210 is a retinoid compound that is a derivative of Tazarotene and exhibits lower anticancer activity. This compound functions as a click chemistry reagent, featuring an Alkyne group that enables it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) when combined with molecules containing Azide groups.
- Retinoid compound: a derivative of Tazarotene.
- Lower anticancer activity: demonstrates reduced activity compared to its parent compound.
- Click chemistry reagent: contains an Alkyne group.
- CuAAc compatibility: capable of undergoing copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules.
- Inhibits cell growth: at a concentration of 10 μM over 5 days, it inhibits the cell growth of B16-F1 TRC cells by 18.1%.
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Medchemexpress LLC Darutoside | 59219-65-7 | 5 MG
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Darutoside is an orally effective diterpene compound with significant anti-inflammatory, analgesic, wound healing promotion, and immunomodulatory activities. It reduces edema and pain by inhibiting COX-2 expression and inflammatory cell migration, and regulates macrophage polarization towards the M2 type by inhibiting the NF-κB pathway, which alleviates inflammation and promotes wound healing. Additionally, it significantly alleviates acute gouty arthritis through multi-target regulation of metabolic networks.
- Inhibits COX-2 expression
- Inhibits NF-κB pathway
- Regulates macrophage polarization towards the M2 type
- Reduces edema and pain
- Promotes wound healing
- Alleviates acute gouty arthritis
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Medchemexpress LLC HY-76948 5mg Medchemexpress, 5-R-Rivaroxaban CAS:865479-71-6 Purity:>98%
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Medchemexpress, HY-76948 5mg 5-R-Rivaroxaban CAS:865479-71-6 5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Josamycin >=90% (HPLC) | 16846-24-5 | MFCD00211043 | 50MG
Josamycin >=90% (HPLC) | Purity: >=90% (HPLC) | Mol Wt: 827.99 | 16846-24-5 | MFCD00211043 | 50MG
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