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Filtered Search Results
Apexbio Technology LLC RITA (NSC 652287) 213261-59-7 5mg
RITA (NSC 652287 CAS 213261-59-7) is a synthetic thiophene-furan derivative identified for its potent antiproliferative activity particularly in renal carcinoma models Its precise molecular target remains unclear but pronounced differential cytotoxicity has been observed across tumor cell lines In vitro RITA exhibits an IC50 of 2 nM in A-498 and 20 nM in TK-10 cells with notable sensitivity compared to other lines (GI50 60 nM) In vivo subcutaneous administration in nude mice bearing A-498 xenografts resulted in complete tumor regression without detectable toxicity RITA is widely used for mechanistic studies of selective cytotoxicity and tumor biology
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Medchemexpress LLC HY-15968 50mg Medchemexpress, Entospletinib CAS:1229208-44-9 Purity:>98%
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Medchemexpress, HY-15968 50mg Entospletinib CAS:1229208-44-9 Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with an IC50 of 7.7 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 2319747-14-1 | Medchem Express | LDC4297 (hydrochloride) | 5mg | 746319286 | HY-12653A | 468.99 | C23H29ClN8O
Ambeed | 6-Bromo-2-methylquinazolin-4(3H)-one | 1g | 552590617 | A151777 | 5426-59-5 | MFCD09996877 | 239.072 | C9H7BrN2O
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Medchemexpress LLC Vortioxetine (Standard) | 508233-74-7 | MFCD22380814 | C18H22N2S | 100 MG
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Vortioxetine (Lu AA 21004) is a multimodal serotonergic agent with antagonistic properties at 5-HT3A and 5-HT7 receptors, partial agonist properties at 5-HT1B receptors, and agonistic properties at 5-HT1A receptors. It also acts as a potent inhibitor of the serotonin transporter (SERT). This product is intended for research and analytical applications, and does not cause cognitive or psychomotor impairment.
- Antagonist of 5-HT3A and 5-HT7 receptors
- Inhibitor of serotonin transporter (SERT)
- Agonist of 5-HT1A receptors
- Partial agonist of 5-HT1B receptors
- Increases cell proliferation and survival
- Stimulates maturation of immature granule cells
- Intended for research and analytical applications
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Medchemexpress LLC HY-11102 10mg Medchemexpress, RO4929097 CAS:847925-91-1 Purity:>98%
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Medchemexpress, HY-11102 10mg RO4929097 CAS:847925-91-1 RO4929097 (RG-4733) is a γ secretase inhibitor with IC50 of 4 nM, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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ILEX LIFE SCIENCES LLC AMPHOTERICIN B 250UG/ML 50ML
PAN-Biotech Amphotericin B for cell culture (Fungizone generic), 250 ug/ml (50 ml). DESCRIPTION: PAN-Biotech Amphotericin B (250 ug/ml) is a generic version of Fungizone that is used in cell culture applications. Amphotericin B is an antifungal agent produced by Streptomyces sp.. Amphotericin B increases fungal plasma membrane permeability by binding to sterols, thereby protecting cell cultures from contamination by yeast and multicellular fungi. APPLICATION: Amphotericin B is often used as an antifungal, anti-yeast and anti-mold agent to prevent fungal contamination of cell cultures. The commonly recommended working concentration ranges from 0.25-2.5 ug/mL (1-10 mL/L). LIQUID/POWDER: Liquid. STERILE: Yes. STORAGE TEMP.: -20°C. MANUFACTURER: PAN-Biotech GmbH. COUNTRY OF ORIGIN: Germany. USAGE: This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures.
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eMolecules 1425043-73-7 | Medchem Express | IPI-3063 | 2mg | 446260058 | HY-111510 | 455.522 | C25H25N7O2
Medchem Express | Demethoxyencecalin | 50mg | 518571246 | HY-77173 | 19013-07-1 | MFCD06200746 | 202.253 | C13H14O2
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Medchemexpress LLC Thalidomide-PEG2-C2-NH2 (TFA) | 2097509-36-7 | 99.1% | 100 MG
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Thalidomide-PEG2-C2-NH2 (TFA) is a high-purity chemical compound, identified as an E3 ligase ligand-linker conjugate. It is designed for laboratory research purposes and exhibits chemical stability under recommended storage conditions.
- High purity of 99.1% (HPLC)
- Stable under recommended storage conditions
- E3 ligase ligand-linker conjugate
- Suitable for laboratory research
- Recommended storage at -20°C under nitrogen
- For solutions, store at -80°C for 6 months or -20°C for 1 month under nitrogen
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Alkali Scientific Spectinomycin Sulfate, 5 G
Spectinomycin Sulfate, 5g, is an antibiotic used for the treatment of bacterial infections, especially those caused by Neisseria gonorrhoeae. It is particularly important in cases where other antibiotics, like penicillin, are ineffective due to resistance. The 5g quantity is suitable for both clinical applications and laboratory research, providing a small yet effective dose for testing bacterial growth inhibition and resistance mechanisms. Spectinomycin acts by interfering with bacterial protein synthesis, and its use is critical in research focused on cell function, protein synthesis, and antimicrobial resistance. This 5g form is widely utilized in microbiology and clinical diagnostic applications.
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Alkali Scientific Rapamycin, 1 Mg
Rapamycin (1mg) is a laboratory reagent primarily used as a cell growth inhibitor in biological research. It works by binding to the mTOR (mechanistic target of rapamycin) protein, inhibiting its activity and thus preventing cell division and growth. This makes it an essential tool in cancer research, immunology, and the study of cell signaling pathways. Rapamycin has also been shown to have immunosuppressive properties, making it useful in transplant medicine to prevent organ rejection. In research, it is used to explore pathways related to aging, metabolism, and diseases associated with uncontrolled cell growth, such as cancer.
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Medchemexpress LLC HY-19791 1mg Medchemexpress, N-Acetyl-Calicheamicin CAS:108212-76-6 Purity:>98%
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Medchemexpress, HY-19791 1mg N-Acetyl-Calicheamicin CAS:108212-76-6 0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Supply Solutions Roche - Hygromycin B; from Streptomyces hygroscopicus; pkg of 20mL (1 g)
Roche - Hygromycin B; from Streptomyces hygroscopicus; pkg of 20mL (1 g)
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Medchemexpress LLC HY-100233 5mg Medchemexpress, IQ-1S (free acid) CAS:23146-22-7 Purity:>98%
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Medchemexpress, HY-100233 5mg IQ-1S (free acid) CAS:23146-22-7 IQ-1S free acid is a prospective inhibitor of NF-κB /activating protein 1 ( AP-1 ) activity with an IC 50 of 2.3±0.41 μM. IQ-1S free acid has binding affinity (K d values) in the nanomolar range for all three JNK s with K d s of 100 nM, 240 nM, and 360 nM for JNK3 , JNK1 , and JNK2 , respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Research Products International Corp Piperacillin, Sodium Salt, 1 Gram
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Piperacillin Sodium Salt is a broad-spectrum β-lactam antibiotic. Piperacillin belongs to the class of extended-spectrum penicillins and inhibits bacterial cell wall synthesis. It achieves this by binding to penicillin-binding proteins (PBPs), enzymes involved in the final stages of peptidoglycan synthesis in the bacterial cell wall. This interference results in structural instability and eventual cell lysis.
Piperacillin Sodium Salt may be used for studying antibiotic susceptibility patterns or as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic.
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Medchemexpress LLC Darutoside | 59219-65-7 | 5 MG
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Darutoside is an orally effective diterpene compound with significant anti-inflammatory, analgesic, wound healing promotion, and immunomodulatory activities. It reduces edema and pain by inhibiting COX-2 expression and inflammatory cell migration, and regulates macrophage polarization towards the M2 type by inhibiting the NF-κB pathway, which alleviates inflammation and promotes wound healing. Additionally, it significantly alleviates acute gouty arthritis through multi-target regulation of metabolic networks.
- Inhibits COX-2 expression
- Inhibits NF-κB pathway
- Regulates macrophage polarization towards the M2 type
- Reduces edema and pain
- Promotes wound healing
- Alleviates acute gouty arthritis
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