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Filtered Search Results
Invivogen Bafilomycin A1 V-ATPase inhibitor 10UG
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Bafilomycin A1 V-ATPase inhibitor 10UG
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eMolecules 154992-24-2 | 4-(3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile | MFCD00925776 | 100mg
Ambeed | 5-Methoxy-1H-pyrazole | 250mg | 600831594 | A158654 | 215610-30-3 | MFCD28011352 | 98.105 | C4H6N2O
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Apexbio Technology LLC Spectinomycin dihydrochloride 21736-83-4 5g
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Spectinomycin dihydrochloride is an aminocyclitol antibiotic derived from Streptomyces spectabilis exerting antibacterial activity by selectively binding to the bacterial 30S ribosomal subunit and disrupting protein synthesis initiation and elongation steps Due to its defined mechanism impacting gram-negative and certain gram-positive bacteria spectinomycin dihydrochloride is commonly utilized in microbiology and cell biology studies for selective inhibition assays bacterial resistance investigations and functional analysis of ribosomal function Experimental studies typically report inhibitory effects against sensitive bacterial strains with IC50 values ranging approximately from 5 to 20 g/mL depending on bacterial species and experimental methodologies It is suitable for research applications involving bacterial cultures protein translation assays and antibiotic resistance profiling
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STEMCELL Technologies Doxorubicin (Hydrochloride), Size: 25 mg
Doxorubicin is an anthracycline antibiotic that intercalates DNA and inhibits DNA topoisomerase II (Burridge et al.; Lorenzo et al.). Doxorubicin exhibits cardiotoxic effects that involve generating reactive oxygen species, inhibiting DNA topoisomerase II, and releasing calcium in the sarcoplasmic reticulum (Burridge et al.). This product is supplied as the hydrochloride salt of the molecule.CANCER RESEARCH· Induces apoptosis in human endothelial cells (Lorenzo et al.).
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STEMCELL Technologies Bleomycin (Sulfate), Size: 5 mg
Bleomycin is a glycopeptide-derived antibiotic, isolated from the bacterium Streptomyces verticillus, that creates DNA strand scission and exhibits antitumor activity against squamous cell carcinomas and malignant lymphomas (Galm et al.). Bleomycin induces lung injury leading to acute inflammatory response and pulmonary fibrosis (Kulkarni et al.). This product is supplied as the sulfate salt of the molecule.CANCER RESEARCH· Induces single- and double-strand DNA breaks in tumor cells (Hecht).DISEASE MODELING· Induces lung fibrosis in mice (Kulkarni et al.).
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Medchemexpress LLC Anisomycin | 22862-76-6 | MFCD00077650 | 265.31 | C14H19NO4 | 10 MG
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Anisomycin is a bacterial antibiotic and potent research reagent that inhibits peptidyl transferase activity of the 80S ribosome, blocking protein synthesis and activating stress-activated kinases (JNK). It is used in cell and biochemical assays to study translation inhibition, stress signaling, apoptosis, and effects on DNA/RNA synthesis. Recommended storage varies for powder and solution forms.
- Potent protein synthesis inhibitor.
- Activates JNK and stress signaling pathways.
- Applicable to cell and biochemical assays for translation studies.
- Documented CAS number for unambiguous identification.
- Stable under recommended storage conditions for powder and solvent solutions.
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Research Products International Corp Blasticidin S Hydrochloride Powder, 50 Milligrams
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Blasticidin S hydrochloride powder is a commonly used antibiotic in the life science marketplace. It is primarily employed as a selective agent in cell culture systems and molecular biology applications.
Blasticidin S is derived from Streptomyces griseochromogenes and is effective against a wide range of organisms, including bacteria, yeast, fungi, and certain higher eukaryotic cells. It works by inhibiting protein synthesis in cells, specifically targeting the 80S ribosome and interfering with the peptidyl transferase activity.
In the life science marketplace, Blasticidin S hydrochloride powder is frequently used in cell culture research and genetic engineering. It is added to growth media to select for cells that have successfully incorporated a Blasticidin S resistance gene, typically as part of a recombinant DNA construct or plasmid vector.
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Sigma Aldrich Fine Chemicals Biosciences Streptozocin ≥75% α-anomer basis, powder | 18883-66-4 | MFCD00006607 | 50mg
Streptozocin ≥75% α-anomer basis, powder | Purity: 98% | Mol Wt: 265.22 | 18883-66-4 | MFCD00006607 | 50mg
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Sigma Aldrich Fine Chemicals Biosciences D-(+)-Turanose >=98% | 547-25-1 | MFCD00006606 | 1G
D-(+)-Turanose >=98% | Purity: >=98% | Mol Wt: 342.3 | 547-25-1 | MFCD00006606 | 1G
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Research Products International Corp Trimethoprim, 5 Grams
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Trimethoprim is a bacteriostatic antibiotic that inhibits bacterial dihydrofolate reductase, an enzyme involved in the synthesis of tetrahydrofolic acid. This acid is crucial for the production of nucleic acids (DNA and RNA) in bacteria. By blocking this enzyme, trimethoprim disrupts the folate synthesis pathway, leading to the inhibition of bacterial growth.
Trimethoprim is frequently used as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic. Its presence in the culture medium allows for the specific isolation of bacteria that lack resistance to trimethoprim.
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STEMCELL Technologies Mifepristone, Size: 1 g
Mifepristone is a progesterone and glucocorticoid receptor antagonist (Ki = 0.64 and 0.1 nM, respectively; Attardi et al.; Song et al.; von Geldern et al.). It has been reported that Mifepristone is used in the treatment of leiomyomata, endometriosis, breast cancer, and meningioma (Mahajan et al.).CANCER RESEARCH· Inhibits the expressions of cyclin-dependent kinase 1 (CDK1) and cyclin-dependent kinase 2 (CDK2), leading to cell cycle arrest and apoptosis in endometrial epithelial cells and stromal cells in adenomyosis (Che et al.).· Induces cell cycle arrest and apoptosis in antiestrogen-resistant breast cancer cells in vitro (Gaddy et al.).
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STEMCELL Technologies Doxorubicin (Hydrochloride), Size: 5 mg
Doxorubicin is an anthracycline antibiotic that intercalates DNA and inhibits DNA topoisomerase II (Burridge et al.; Lorenzo et al.). Doxorubicin exhibits cardiotoxic effects that involve generating reactive oxygen species, inhibiting DNA topoisomerase II, and releasing calcium in the sarcoplasmic reticulum (Burridge et al.). This product is supplied as the hydrochloride salt of the molecule.CANCER RESEARCH· Induces apoptosis in human endothelial cells (Lorenzo et al.).
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ALADDIN SCIENTIFIC CORPORATION Ampicillin Na, 25g
Ampicillin is reported as slightly soluble in water practically insoluble in alcohol chloroform ether and fixed oils but soluble in dilute acids or bases The solution should not be autoclaved a stock solution should be sterilized through filtration and stored frozen where it will be stable for months Used to select for ampicillin resistance in mutated and transformed cells
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Gold Biotechnology Inc Penicillin G Sodium Salt, USP Grade 50 g
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Penicillin G is a β-lactam antibiotic produced by the Penicillium fungus. It has shown efficacy against a variety of Streptococcus species as well as non-penicillinase producing Staphylococcus species.
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Medchemexpress LLC RU.521 10MG
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RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation | CAS 2262452-06-0 | SMILES O=C1OC(C2=C(O)N(C3=NC4=CC=C(Cl)C(Cl)=C4N3)N=C2C)C5=C1C=CC=C5
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