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Filtered Search Results
AdipoGen Geldanamycin
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Chemical. CAS 30562-34-6. Formula C29H40N2O9. MW 560.6. Isolated from Streptomyces hygroscopicus. Antibiotic. Potent antitumor compound. pp60src tyrosine kinase inhibitor. Inhibits c-mycgene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds specifically to heat shock protein 90 HSP90 and to its endoplasmic reticulum homolog GP96 GRP94. Destabilizes several oncogene and proto-oncogene products. Potent nuclear hormone receptor family inhibitor.
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Biotium LYSOVIEW 680 1000X DMSO 50UL
LYSOVIEW 680 1000X DMSO 50UL
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Medchemexpress LLC (R)-6-chloro-N-(4-fluoro-2-(methylsulfonyl)phenyl)-7-hydroxy-4-oxo-4H-chromene-2-carboxamide | 2438637-65-9 | 99.8% | 435.81 g/mol | C19H11ClFNO6S | 5 MG
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PGAM1-IN-1 is a small-molecule inhibitor of phosphoglycerate mutase 1 (PGAM1) with an enzymatic IC50 of 6.4 μM and demonstrated cellular activity (H1299 proliferation IC50 14.1 ± 1.9 μM). Supplied as a high-purity research reagent, the compound has molecular formula C19H11ClFNO6S and molecular weight 435.81 g/mol. For research use only.
- Inhibits phosphoglycerate mutase 1 with an IC50 of 6.4 μM.
- Shows H1299 cell proliferation inhibition (IC50 14.1 ± 1.9 μM).
- High purity (>99.8%).
- Available as solid and as a 10 mM solution in DMSO.
- Molecular formula C19H11ClFNO6S; molecular weight 435.81 g/mol.
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Cayman Chemical 3-O- 5-BromonthrnIloyl-2 700ug
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A dATP derivative
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Cayman Chemical 8 6AmInohexylthIogunosIn 700ug
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An aminohexylthiol-substituted derivative of GTP; has been used in the synthesis of biotinylated derivatives of GTP
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Sigma Aldrich Fine Chemicals Biosciences Moxifloxacin hydrochloride United States Pharmacopeia (USP) Reference Standard | 186826-86-8 | MFCD00949117 | 200MG
Moxifloxacin hydrochloride United States Pharmacopeia (USP) Reference Standard | Mol Wt: 437.89 | 186826-86-8 | MFCD00949117 | 200MG
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Medchemexpress LLC Ponatinib hydrochloride (AP24534 hydrochloride) | 1114544-31-8 | 99.76% | 569.02 | 500 MG
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Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride salt of ponatinib. It is an orally active multi-targeted kinase inhibitor with IC50 values of 0.37 nM for Abl, 1.1 nM for PDGFRα, 1.5 nM for VEGFR2, 2.2 nM for FGFR1, and 5.4 nM for Src.
- Orally active multi-targeted kinase inhibitor.
- Inhibits Abl with an IC50 of 0.37 nM.
- Targets PDGFRα with an IC50 of 1.1 nM.
- Inhibits VEGFR2 with an IC50 of 1.5 nM.
- Targets FGFR1 with an IC50 of 2.2 nM.
- Inhibits Src with an IC50 of 5.4 nM.
- Reduced viability, migration, and function of human endothelial cells in vitro.
- Protects mice from lethal influenza infection by inhibiting cytokine storm in vivo.
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Medchemexpress LLC Ponatinib hydrochloride (AP24534 hydrochloride) | 1114544-31-8 | 99.8% | 569.02 | 100 U
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Ponatinib hydrochloride is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively. It is for research use only and not sold to patients.
- Orally active multi-targeted kinase inhibitor
- IC50s: 0.37 nM for Abl, 1.1 nM for PDGFRα, 1.5 nM for VEGFR2, 2.2 nM for FGFR1, and 5.4 nM for Src
- Reduces viability, migration, and function of human endothelial cells in vitro
- Protects mice from lethal influenza infection by inhibiting cytokine storm in vivo
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Research Products International Corp RPI Cefuroxime, Sodium Salt, 20 Grams
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Cefuroxime Sodium Salt is a second-generation cephalosporin antibiotic. Cefuroxime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This interference disrupts the final stages of peptidoglycan synthesis in the bacterial cell wall, leading to structural instability and eventual cell lysis.
Cefuroxime is effective against a wide spectrum of bacteria, both Gram-positive and Gram-negative. In microbiology and research settings, it is sometimes used as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic. Additionally, Its inclusion allows for the specific growth of bacteria lacking resistance to cefuroxime.
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Sigma Aldrich Fine Chemicals Biosciences Streptozocin >=75% alpha-anomer basis, >=98% (HPLC), powder | 18883-66-4 | MFCD00006607 | 500MG
Streptozocin >=75% alpha-anomer basis, >=98% (HPLC), powder | Purity: >=75% alpha-anomer basis; >=98% (HPLC) | Mol Wt: 265.22 | 18883-66-4 | MFCD00006607 | 500MG
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Medchemexpress LLC Rifampicin (Standard) | 13292-46-1 | 95.5% | 100 MG
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Rifampicin (Standard) is the analytical standard of Rifampicin, intended for research and analytical applications. It is a potent, broad-spectrum antibiotic effective against bacterial pathogens. Rifampicin also exhibits anti-influenza virus and anti-orthopoxvirus activities.
- Analytical standard grade for assay reference
- Used in qualitative, quantitative, and methodological research experiments involving HPLC, GC, and MS
- Potent and broad-spectrum antibiotic against bacterial pathogens
- Exhibits anti-influenza virus activities
- Shows anti-orthopoxvirus activity
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Sigma Aldrich Fine Chemicals Biosciences Cyclophosphamide monohydrate bulk package | 6055-19-2 | MFCD00149395 | 10G
Cyclophosphamide monohydrate bulk package | Purity: 97.0-103.0% (HPLC) | Mol Wt: 279.1 | 6055-19-2 | MFCD00149395 | 10G
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Sigma Aldrich Fine Chemicals Biosciences Ceftiofur sodium trihydrate United States Pharmacopeia (USP) Reference Standard | 104010-37-9 (anhydrous) | 100MG
Ceftiofur sodium trihydrate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 599.59 | 104010-37-9 (anhydrous) | 100MG
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Sigma Aldrich Fine Chemicals Biosciences Triamterene >=99% | 396-01-0 | MFCD00006708 | 10G
Triamterene >=99% | Purity: >=99% | Mol Wt: 253.26 | 396-01-0 | MFCD00006708 | 10G
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Medchemexpress LLC Pptn hydrochloride | 1992047-65-0 | 99.89% | 511.96 | 10 MG
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PPTN hydrochloride is a potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. It shows no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. It also exhibits anti-inflammatory and anti-immune activity.
- Potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist
- Exhibits no agonist or antagonist effect at P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors
- Inhibits UDP-glucose-promoted chemotaxis in differentiated HL-60 human promyelocytic leukemia cells with IC50s of ~1 nM (in the presence of 10 μM UDP-glucose) and ~4 nM (in the presence of 100 μM)
- Significantly decreases the ratios of p-ERK1/2 to ERK1/2 and p-p38 to p38 at 10 μM
- Anti-inflammatory activity
- Anti-immune activity
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