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Filtered Search Results
Medchemexpress LLC 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine | 152121-53-4 | MFCD12405019 | 98.6% | 360.34 | C20H13FN4O2 | 500 MG
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PD 169316 is a potent, cell-permeable, and selective p38 MAP kinase inhibitor used as a research reagent and analytical standard for biochemical and cell-based studies. It inhibits p38 MAPK with a reported IC50 of approximately 89 nM and is supplied in multiple pack sizes for laboratory use.
- Potent, selective p38 MAP kinase inhibitor.
- Cell-permeable small molecule suitable for cell-based assays.
- Reported IC50 approximately 89 nM against p38 MAPK.
- High purity, typically 98.6% by HPLC.
- Molecular weight 360.34 g/mol and formula C20H13FN4O2.
- Provided as an analytical standard in multiple pack sizes, including 500 mg.
- Intended for research use only, not for human consumption.
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TOKU-E Salinomycin ReadyMade™ Solution | Salinomycin Sodium | CS 55721-31-8 | 2 mg/ML in water | sterile-filtered | 0.5 ML
Salinomycin ReadyMade™ Solution | Salinomycin Sodium | CS 55721-31-8 | 2 mg/ML in water | sterile-filtered | 0.5 ML
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Medchemexpress LLC Gw274150 phosphate | 438542-15-5 | 98.0% | 50 MG
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GW274150 phosphate is a selective, orally active inhibitor of inducible nitric oxide synthase (iNOS) supplied as the phosphate salt for research use. It is used in pharmacology studies to probe iNOS-mediated pathways and has reported activity (IC50 ≈ 2.19 μM; Kd ≈ 40 nM).
- Selective inhibitor of inducible nitric oxide synthase (iNOS).
- Reported IC50 2.19 μM and Kd 40 nM.
- High purity (~98.0%) with manufacturer-provided COA.
- Molecular weight 317.30 g·mol⁻¹; formula C8H20N3O6PS.
- Available in small research pack sizes, including 50 MG and solution formats.
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AdipoGen Nocodazole,Chemical. CAS: 31430-18-9
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Nocodazole, AdipoGen Life Sciences. Chemical. CAS: 31430-18-9. Formula: C14H11N3O3S. MW: 301.3. Microtubule inhibitor. Antitumor compound. Mitosis inhibitor. Arrests the cell cycle at G2/M phase. Promotes tubulin depolymerization. Induces fragmentation of the Golgi complex. Inhibits the T cell antigen receptor. Stimulates the intrinsic GTPase activity of tubulin. Activates the JNK/SAPK signaling pathway. Apoptosis inducer. Autophagy inhibition through prevention of autophagosome-lysosome fusion.
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Medchemexpress LLC Ne 52-qq57 | 1401728-56-0 | 99.9% | 416.52 g/mol | C24H28N6O | 10 MG
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NE 52-QQ57 is a selective, orally available antagonist of GPR4 with an IC50 of ~70 nM and reported anti-inflammatory activity; supplied as a high-purity research compound for in vitro and in vivo pharmacology studies.
- Selective GPR4 antagonist (IC50 70 nM).
- High purity (99.9%).
- Molecular weight 416.52 g/mol.
- Soluble in DMSO (20 mg/mL).
- Stable storage: powder at -20°C (up to 3 years).
- Demonstrated oral efficacy in animal models.
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Enzo Life Sciences Microcystin-LR, (500µg), CAS Number: 101043-37-2
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Inhibitor of PP1 and PP2A. Heptapeptide ester hepatotoxin. Tumor promoter. Equally potent and selective inhibitor of protein phosphatase 1 (PP1) and 2A (PP2A). PP2B is less sensitive and PP2C is not inhibited up to 4µM. Useful for affinity-purification of PP2A. The product is not cell permeable except in liver cells, which appear to have a functional uptake system. Is absorbed by hepatocytes.7.7. Long Term Storage: -20°C
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Enzo Life Sciences Vinyl-L-NIO (25mg). CAS: 728944-69-2
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Very selective and potent neuronal nitric oxide synthase (nNOS/NOS I) inhibitor. Alternative name: N5-(1-Imino-3-butenyl)-L-ornithine, L-VNIO. Formula: C9H17N3O2 . HCl. MW: 235.7. Purity: ≥95% (TLC). Appearance: Off-white solid to clear film. Solubility: Soluble in water, 100% ethanol (30mg/ml), DMSO (50mg/ml) or dimethyl formamide (50mg/ml). Long Term Storage: +4°C. Handling: Very hygroscopic. Open only in anhydrous atmosphere.
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Bioworld Enrofloxacin, 5 g
Specification:Synonym:1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinolonecarboxylic Acid; CFPQAn antibiotic that acts against gram-positive and -negative bacteriaHeavy metals: <0.002%Typical working concentration: 5- 25μg/ml Appearance: SolidBoiling Point : 560.46 °C at 760 mmHg (Predicted)Density : 1.39 g/cm3 (Predicted)Melting Point: 218.9-221.1 °CRTECS Number: VB1993650
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Quality Biological Inc Penicillin/Streptomycin Mixture, 100 mL
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Penicillin-Streptomycin acts in two ways, penicillin inhibits bacterial cell wall synthesis, while, streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding. ¿ 100X concentration of mixture of penicillin and streptomycin ¿ Applications: This solution contains 10,000 units/mL of penicillin and 10,000 ¿g/mL of streptomycin. ¿ Storage Conditions: -10¿C to -20¿C ¿ Shipping Condition: on dry ice ¿ Sterile Filtered ¿ Product and/or packaging contains recycled/renewable content ¿ Product and/or packaging is recyclable or reduces waste ¿ Product and/or packaging is safer to human and environmental health ¿ UNSPSC: 41122100 ¿ ¿ Max Shelf Life: 24 months
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Cayman Chemical AzIthromycIn 25mg
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A macrolide antibiotic; active against S. pneumoniae, S. aureus, N. gonorrhoeae, M. pneumoniae, H. pylori, C. trachomatis, and H. influenzae in vitro (MIC90s = S. pyogenes, S. pneumoniae, E. faecalis, or H. influenzae infection (ED50s = 0.78, 8.7, 12.7, and 30.3 mg/kg, respectively); decreases plasma levels of IL-6, TNF-α, and IL-1β and increases survival in mouse model of LPS-induced sepsis at 100 mg/kg
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Sigma Aldrich Fine Chemicals Biosciences Erythromycin potency 85025G
Chemical structure macrolide
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Selleck Chemical LLC Tozasertib (VX-680) S1048-250mg
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Tozasertib (VX-680) is a pan-Aurora inhibitor mostly against Aurora A with Kiapp of 0 6 nM in a cell-free assay less potent towards Aurora B/Aurora C and 100-fold more selective for Aurora A than 55 other kinases The only exceptions are Fms-related tyrosine kinase-3 (FLT-3) and BCR-ABL tyrosine kinase which are inhibited by the Tozasertib with both Ki of 30 nM Tozasertib induces apoptosis and autophagy Phase 2
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Research Products International Corp Ampicillin, Sodium Salt, 1 KG
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Ampicillin, Sodium Salt is a semi-synthetic penicillin antibiotic effective against a broad range of Gram-positive and Gram-negative bacteria. Supplied as a powder, it is commonly used in molecular biology, microbiology, and genetic engineering. It serves as a selective agent in plasmid-based cloning and helps prevent bacterial contamination in cell cultures. By inhibiting bacterial cell wall synthesis, it ensures the purity of cultures and enables selection of Ampicillin-resistant strains. Key features include broad-spectrum activity, DNase/RNase-free quality, and good stability in aqueous solution, allowing for flexible handling.
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eMolecules 70356-03-5 | Cefaclor monohydrate | Combi-Blocks, Inc. | MFCD00071999 | 385.820 | C15H16ClN3O5S | 98.000 | O.N[C@@H](C(=O)N[C@H]1[C@H]2SCC(Cl)=C(N2C1=O)C(O)=O)c1ccccc1 | 1g | 586079375
Cefaclor monohydrate | Combi-Blocks, Inc. | 70356-03-5 | MFCD00071999 | 385.820 | C15H16ClN3O5S | 98.000 | O.N[C@@H](C(=O)N[C@H]1[C@H]2SCC(Cl)=C(N2C1=O)C(O)=O)c1ccccc1 | 1g | 586079375
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Medchemexpress LLC Protac-o4i2 | 2785323-62-6 | 99.6% | C29H29ClN6O5S | 100 MG
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PROTAC-O4I2 is a PROTAC (proteolysis-targeting chimera) that targets splicing factor 3B1 (SF3B1). It induces FLAG-SF3B1 degradation with an IC50 value of 0.244 μM in K562 cells and cellular apoptosis in K562 WT cells. It introduces Thalidomide to ubiquitin E3 ligase cereblon (CRBN) which selectively degrades SF3B1 and inhibits tumor growth in cells.
- Degrades and inhibits SF3B1 in K562 cells.
- Exhibits anti-proliferation effects on SF3B1 WT, SF3B1 OE, and SF3B1 K700E cells.
- Induces FLAG-SF3B1 degradation.
- Increases survival by interfering with tumor maintenance and proliferation in a Drosophila intestinal tumor model.
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