Antibiotics
Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.
Quantity
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- (1)
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- (1)
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- (145)
- (7)
- (13)
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- (1)
- (28)
- (188)
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- (1)
- (23)
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- (23)
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- (30)
- (1)
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- (24)
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- (1)
Physical Form
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Type
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- (17)
- (1)
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- (7)
- (1)
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- (5)
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- (1)
- (2)
- (1)
- (9)
- (3)
- (2)
- (2)
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- (12)
- (2)
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- (2)
- (7)
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- (2)
- (1)
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- (2)
- (1)
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- (2)
- (1)
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- (1)
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- (2)
- (2)
- (1)
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- (7)
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- (2)
- (3)
- (1)
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- (2)
- (2)
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- (3)
- (2)
- (2)
- (3)
- (2)
- (1)
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- (2)
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- (2)
- (1)
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- (4)
- (4)
- (2)
- (1)
- (3)
- (2)
- (1)
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- (9)
- (2)
- (1)
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- (7)
- (1)
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- (1)
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- (2)
- (1)
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- (16)
- (1)
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- (2)
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- (11)
- (1)
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- (3)
- (2)
- (1)
- (4)
- (1)
- (11)
- (7)
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- (1)
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- (1)
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- (1)
Molecular Weight (g/mol)
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- (1)
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Color
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- (1)
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- (3)
- (398)
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- (34)
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5,236
MEDCHEMEXPRESS LLC -JQ-1-ALDEHYDE 50 mg
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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-JQ-1-ALDEHYDE 50MG
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5,237
MEDCHEMEXPRESS LLC BIPERIDEN 50 mg
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BIPERIDEN 50MG
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5,238
MEDCHEMEXPRESS LLC ERYTHROMYCIN OXIME 25 mg
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ERYTHROMYCIN OXIME 25MG
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5,239
MEDCHEMEXPRESS LLC 15-KETO BIMATOPROST- 1 mg
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15-KETO BIMATOPROST- 1MG
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5,240
MEDCHEMEXPRESS LLC 2 5 -DIDEOXYADENOSI 50 mg
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2 5 -DIDEOXYADENOSI 50MG
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5,241
MEDCHEMEXPRESS LLC THIAMPHENICOL GLYCIN 10MM 1ML
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THIAMPHENICOL GLYCIN 10MM 1ML
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5,242
MEDCHEMEXPRESS LLC CARMUSTINE 500 mg
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CARMUSTINE 500MG
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5,243
MEDCHEMEXPRESS LLC Streptozotocin | 18883-66-4 | MFCD00006709 | ≥98% | 265.22 | 5 G
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Streptozotocin (STZ) is an antibiotic commonly used in experimental animal models to induce diabetes. It enters B cells via the glucose transporter (GLUT2) and causes DNA alkylation, leading to the apoptosis of β cells. This compound is suitable for constructing models of both type 1 and type 2 diabetes.
- Induces cytotoxicity, oxidative stress, and mitochondrial dysfunction in HepG2 cells.
- Specifically transported by GLUT2 in GLUT2-expressing cells.
- Highly water-soluble and often dissolved in cold acidic citric acid buffer (pH 4.0-4.7).
- Distributes widely throughout the body, including crossing the blood-brain barrier and placenta.
- Undergoes chemical modification in the liver, converting into an active form that causes DNA methylation and damages pancreatic β-cells.
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5,244
MEDCHEMEXPRESS LLC TBI-223 | 2071265-08-0 | 99.7% | 365.36 g/mol | 100 MG
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TBI-223 is an orally active oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb). TBI-223 exhibits an IC50 of 68 μg/mL for inhibiting mitochondrial protein synthesis (MPS) in HepG2 cells. TBI-223 is effective in three mouse models (bloodstream infection, skin infection, and bone infection) of methicillin-resistant staphylococcus aureus infection. TBI-223 can be used for the study of tuberculosis.
- Orally active oxazolidinone antibiotic
- Antimicrobial
- Active against Mycobacterium tuberculosis (Mtb)
- Exhibits an IC50 of 68 μg/mL for inhibiting mitochondrial protein synthesis (MPS) in HepG2 cells
- Effective in three mouse models of methicillin-resistant staphylococcus aureus infection
- Can be used for the study of tuberculosis
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5,245
MEDCHEMEXPRESS LLC AG-636 | 1623416-31-8 | 98.1% | 343.38 | 50 MG
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AG-636 is a potent, reversible, selective, and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. It demonstrates strong anticancer effects.
- Exhibits significant growth-inhibitory activity in cancer cell lines.
- Results in robust tumor growth inhibition in xenograft lymphoma tumor models.
- Suitable for laboratory research applications.
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5,246
MEDCHEMEXPRESS LLC GSK4112 (SR6452) | 1216744-19-2 | 99.9% | C18H21ClN2O4S | 100 MG
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GSK4112, also known as SR6452, is identified as a Rev-erbα agonist with an EC50 value of 0.4 μM. It serves as a valuable chemical tool for investigating the role of Rev-erbα in various biological processes, including transcriptional repression, the regulation of circadian rhythms, and metabolic pathways.
- Interacts with Rev-erbα with an EC50 of 0.4 μM.
- Represses the expression of bmal1 and target genes associated with gluconeogenesis, recruits HDAC3, and modulates Rev-erbα's effect on hepatic gene expression oscillation.
- Reduces glucose output in murine hepatocytes.
- Attenuates Fas-induced hepatic damage in male C57BL/6 mice.
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5,247
MEDCHEMEXPRESS LLC Isavuconazole-d4 | 1346598-58-0 | 99.9% | C22H13D4F2N5OS | 1 MG
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Isavuconazole-d4 (BAL-4815-d4) is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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5,248
MEDCHEMEXPRESS LLC STING agonist-7 | 2767442-46-4 | 97.22% | C17H12N4O4 | 100 MG
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STING agonist-7 is a non-nucleotide STING agonist that selectively binds to mouse STING, but not human STING. This compound poorly penetrates cell membranes. It is intended for research use only.
- Selectively binds to mouse STING
- Does not bind to human STING
- Poorly penetrates cell membranes
- Active in biochemical assays
- Inactive in cellular reporter assays
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5,249
MEDCHEMEXPRESS LLC NRX-1532 | 3083833-54-6 | 98.01% | C16H11F3N4O2 | 100 MG
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NRX-1532 is a small molecule that enhances the interaction between β-catenin and β-TrCP.
- Small molecule enhancer of β-catenin:β-TrCP interaction.
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5,250
MEDCHEMEXPRESS LLC Vu0155041 | 1093757-42-6 | 99.10% | C14H15Cl2NO3 | 50 MG
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VU0155041 is a potent, selective positive allosteric modulator (PAM) of mGluR4, with EC50s of 798 nM and 693 nM for human and rat mGluR4, respectively. VU0155041 has potential for the research of Parkinson's disease (PD).
- Potent and selective positive allosteric modulator (PAM) of mGluR4
- EC50s of 798 nM for human mGluR4
- EC50s of 693 nM for rat mGluR4
- Potential for Parkinson's disease research
- Does not affect NMDA receptor currents in striatal medium spiny neurons at 10 μM in vitro
- Reverses catalepsy induced by dopamine D2 receptor antagonist Haloperidol in rats
- Reverses Reserpine-induced akinesia in rats
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