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Filtered Search Results
Medchemexpress LLC HY-119940 10mg Medchemexpress, MC180295 CAS:2237942-08-2 Purity:>98%
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Medchemexpress, HY-119940 10mg MC180295 CAS:2237942-08-2 MC180295 ((rel)-MC180295) is a potent and selective CDK9-Cyclin T1 inhibitor, with an IC50 of 5 nM, at least 22-fold more selective for CDK9 over other CDKs. MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Fingolimod (FTY720 free base) | 162359-55-9 | MFCD09262100 | 99.97% | 308.4 | 50 MG
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Fingolimod (FTY720 free base) is a brain-penetrant sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also acts as a PAK1 activator and an immunosuppressant. It is for research use only.
- Brain-penetrant sphingosine 1-phosphate (S1P) antagonist
- IC50 of 0.033 nM in K562 and NK cells
- PAK1 activator
- Immunosuppressant
- For research use only
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Medchemexpress LLC Bimatoprost | 155206-00-1 | 99.9% | 100 MG
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Bimatoprost is a prostaglandin analog that reduces intraocular pressure by regulating scleral and trabecular outflow. It is used in the study of open-angle glaucoma, ocular hypertension, and other forms of glaucoma. Topical application of bimatoprost can induce fat atrophy and cause a deepening of the eyelid sulcus. In vitro studies show that Bimatoprost dose-dependently upregulates the mRNA levels of cellular matrix metalloproteinases MMP1 and MMP14 in human trabecular meshwork (TM), iris fibroblasts (SF), and ciliary muscle (CM) cells.
- Reduces intraocular pressure
- Regulates scleral and trabecular outflow
- Suitable for study of open-angle glaucoma and ocular hypertension
- Upregulates mRNA of cellular matrix metalloproteinases MMP1 and MMP14 in TM, SF, and CM cells
- IOP response dependent on FP receptor expression
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Sigma Aldrich Fine Chemicals Biosciences Triclocarban Related Compound A United States Pharmacopeia (USP) Reference Standard | 1219-99-4 | 15MG
Triclocarban Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 281.14 | 1219-99-4 | 15MG
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Medchemexpress LLC HY-18791 5mg Medchemexpress, c-Fms-IN-1 CAS:885703-64-0 Purity:>98%
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Medchemexpress, HY-18791 5mg c-Fms-IN-1 CAS:885703-64-0 c-Fms-IN-1 is a FMS kinase inhibitor with an IC 50 of 0.0008 μM [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100574A 10mg Medchemexpress, Cl-amidine (hydrochloride) CAS:1373232-26-8 Purity:>98%
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Medchemexpress, HY-100574A 10mg Cl-amidine (hydrochloride) CAS:1373232-26-8 Cl-amidine (hydrochloride) is a peptidylarginine deminase (PAD) inhibitor, with an IC 50 5.9 μM for PAD4. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 91832-40-5 | AstaTech | CEFDINIR | 1g | 200609677 | 44027 | 97 | 395.41 | C14H13N5O5S2
AstaTech | CEFDINIR | 1g | 200609677 | 44027 | 97.000 | 91832-40-5 | 395.410 | C14H13N5O5S2
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Medchemexpress LLC Oligomycin A | 579-13-5 | 99.91% | 791.06 | 100 MG
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Oligomycin A (MCH 32), produced by Streptomyces, functions as a mitochondrial F0F1-ATPase inhibitor with a Ki of 1 μM. It also demonstrates anti-fungal activity. For research use only; not sold to patients.
- Acts as a mitochondrial F0F1-ATPase inhibitor (Ki: 1 μM).
- Exhibits anti-fungal activity.
- Shows cytotoxic effects on NCI-60 cell lines with a GI50 of 10 nM.
- Inhibits the activity of Triton X-100-solubilized ATPase with a Ki of 0.1 μM.
- Inhibits the ability of spermatozoa to achieve feasible in vitro capacitation (IVC) at 2.4 μM.
- Suppresses progesterone-induced in vitro acrosome exocytosis (IVAE) and associated O2 consumption and ATP levels.
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Medchemexpress LLC 8-Cyclopentyl-1,3-dipropylxanthine | 102146-07-6 | MFCD00055117 | ≥98.0% | 304.39 g/mol | C16H24N4O2 | 100 MG
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DPCPX (PD 116948) is a xanthine-derived research compound that functions as a potent and selective adenosine A1 receptor antagonist. It is used in pharmacology and neuroscience research to block A1 receptor-mediated signaling in vitro and in vivo, supporting receptor binding, electrophysiology, and behavioral studies.
- Potent and selective adenosine A1 receptor antagonist (Ki ≈ 0.46 nM).
- Xanthine-derived compound for pharmacology and neuroscience research.
- Suitable for receptor binding, electrophysiology, and behavioral assays.
- Molecular formula C16H24N4O2; molecular weight 304.39 g/mol.
- Typically soluble in DMSO for assay preparation.
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Medchemexpress LLC Isavuconazole-d4 | 1346598-58-0 | 99.9% | C22H13D4F2N5OS | 1 MG
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Isavuconazole-d4 (BAL-4815-d4) is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000739252 AZITHROMYCIN IMPURIT 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000723905 CLARITHROMYCIN IMPUR 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000723953 ERYTHROMYCIN B 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000723956 AZITHROMYCIN IMPURIT 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000738048 KANAMYCIN DISULFATE 1KG
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