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Filtered Search Results
Medchemexpress LLC Carboxyamidotriazole Orotate | 187739-60-2 | 99.7% | 580.76 | 5 MG
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Carboxyamidotriazole Orotate is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. It functions as a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. This product demonstrates anti-tumor, anti-inflammatory, and antiangiogenic effects.
- Functions as a cytostatic inhibitor of nonvoltage-operated calcium channels.
- Inhibits calcium channel-mediated signaling pathways.
- Exhibits anti-tumor effects.
- Exhibits anti-inflammatory effects.
- Exhibits antiangiogenic effects.
- Inhibits cell proliferation of LAMA84R and K562R cell lines.
- Reduces phosphorylation of CrkL.
- Shows dose-dependent inhibition of total and phosphorylated Bcr-Abl levels.
- Displays antitumor activity on CML xenografts.
- Increased survival in animal models.
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Research Products International Corp Hygromycin B, Powder Form, 1 Gram
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Hygromycin B is a broad-spectrum antibiotic derived from Streptomyces hygroscopicus, effective against bacteria, yeast, and higher eukaryotes. It is widely used in molecular biology, genetic engineering, and cell culture as a selective agent. Hygromycin B targets protein synthesis, and cells transformed with a hygromycin resistance gene—encoding hygromycin phosphotransferase—can survive treatment. This enables selection and maintenance of genetically modified cells. It is also used to prevent bacterial and fungal contamination in cultures, supporting the purity of cell lines in research applications.
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Medchemexpress LLC Hygromycin A | 6379-56-2 | 511.48 | 25 MG
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Hygromycin A is a *Borrelia burgdorferi*-selective antibiotic that is also a spirochete-specific antibacterial. It contributes to gut health and is utilized in Lyme disease research. In vivo, Hygromycin A selectively eliminates *Borrelia burgdorferi* and positively influences gut microbiota composition, promoting eubiosis.
- Selective antibiotic for *Borrelia burgdorferi*
- Spirochete-specific antibacterial
- Contributes to gut health
- Used for Lyme disease research
- Promotes eubiosis by impacting gut microbiota
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Medchemexpress LLC Lexithromycin (erythromycin A 9-methoxime) | 53066-26-5 | 97.6% | 762.97 g/mol | C38H70N2O13 | 100 MG
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Lexithromycin is an erythromycin A derivative with antibacterial activity, provided as a research-grade reference compound for laboratory and analytical applications. It is offered as a solid or as a prepared solution and has a reported purity of 97.57%.
- Antibacterial erythromycin A derivative.
- Reported purity 97.57%.
- Available as a solid and as a 10 mM solution in DMSO.
- Formula C38H70N2O13 and molecular weight 762.97 g/mol.
- Intended for research and analytical use; not for human or veterinary use.
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Medchemexpress LLC PF-4191834 100mg | 1029317-21-2 | 100 MG
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PF-4191834 is an orally active, non-iron-chelating, non-redox inhibitor of 5-lipoxygenase (5-LOX) with reported IC50 = 229 nM and high selectivity versus 12-LOX and 15-LOX. It is used in enzyme, cell-based, and in vivo inflammation models for research on 5-LOX-mediated pathways.
- Orally active 5-LOX inhibitor (IC50 = 229 nM).
- Approximately 300-fold selectivity over 12-LOX and 15-LOX.
- High purity (99.77%).
- Available as solid; common package 100 MG.
- Molecular weight 393.5 g/mol; formula C22H23N3O2S.
- Recommended storage: powder at -20°C for long-term stability.
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eMolecules 1261289-04-6 | Medchem Express | O-304 | 5mg | 446260236 | HY-112233 | 380.24 | C16H11Cl2N3O2S
Medchem Express | 23-cGAMP | 1mg | 788477971 | HY-100564 | 1441190-66-4 | 674.417 | C20H24N10O13P2
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eMolecules 2407433-00-3 | Medchem Express | T025 | 5mg | 482204018 | HY-112296 | 382.431 | C21H18N8
1-Hydroxy-2,1-benzoxaborolane | Ambeed | 5735-41-1 | MFCD01075677 | 133.940 | C7H7BO2 | 98.000 | OB1OCc2ccccc12 | 1g | 531648017
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Medchemexpress LLC Oct3/4-inducer-1 | 1016535-83-3 | 98.12% | 241.26 | 50 MG
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Oct3/4-inducer-1 (compound 2) is a potent Oct3/4 inducer. It promotes the expression and stabilization of Oct3/4 and enhances its transcriptional activity in diverse human somatic cells.
- Potent Oct3/4 inducer.
- Promotes expression and stabilization of Oct3/4.
- Enhances transcriptional activity in diverse human somatic cells.
- For research use only.
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eMolecules 1029939-86-3 | Medchem Express | Artefenomel | 5mg | 482204426 | HY-16762 | 469.622 | C28H39NO5
Ambeed | 2-Hydroxycyclopent-2-en-1-one | 100mg | 525085790 | A169331 | 10493-98-8 | MFCD16251523 | 98.101 | C5H6O2
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eMolecules 163768-50-1 | Medchem Express | Auristatin F | 5mg | 446266042 | HY-15583 | MFCD25976745 | 746.003 | C40H67N5O8
AstaTech | 5-AMINO-3-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER | 1g | 268497954 | 71282 | 95.000 | 23286-70-6 | MFCD01210846 | 169.184 | C7H11N3O2
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Medchemexpress LLC 2-Pyrazinemethanol, 5-[(2R)-4-[4,5-dimethyl-6-(phenylmethyl)-3-pyridazinyl]-2-methyl-1-piperazinyl]-a,a-dimethyl- | 1204975-42-7 | 98.92% | 432.56 | 50 MG
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LEQ506 is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively. It inhibits Hedgehog (Hh) signaling in a human cell line (HEPM) and shows a tendency to preferentially inhibit Gli1 rather than Ptch1 mRNA. It is efficacious in decreasing Gli1 mRNA by approximately 70% to 80%.
- Second-generation inhibitor of smoothened (Smo).
- IC50s of 2 nM (human smo) and 4 nM (mouse smo).
- Inhibits Hedgehog (Hh) signaling in a human cell line.
- Efficacious in decreasing Gli1 mRNA by approximately 70% to 80%.
- Shows a tendency to preferentially inhibit Gli1 over Ptch1 mRNA.
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Research Products International Corp Puromycin Dihydrochloride, 25 Milligrams
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Puromycin Dihydrochloride is a potent antibiotic. It is an amino nucleoside antibiotic that mimics the 3'-end of aminoacyl-tRNA. It enters the ribosomal A site during translation, causing premature chain termination and inhibiting protein synthesis. Puromycin is incorporated into growing polypeptide chains, leading to the release of incomplete and nonfunctional peptides.
Widely used as a tool in cell biology to study protein synthesis and investigate translation processes. Its ability to terminate protein synthesis at the ribosome makes it valuable for various applications, including pulse-chase experiments and the analysis of nascent peptides. Puromycin resistance genes are often used as selectable markers in genetic engineering. Cells expressing the resistance gene can survive and proliferate in the presence of Puromycin, allowing for the selection of transfected or transduced cells.
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eMolecules 2253879-65-9 | Medchem Express | BCL6-IN-4 | 5mg | 591912006 | HY-136640 | 503.04 | C25H35ClN6O3
Medchem Express | Trimipramine (maleate) | 100mg | 446273733 | HY-B1213 | 521-78-8 | MFCD00082376 | 410.514 | C24H30N2O4
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Medchemexpress LLC Prostaglandin D2 | 41598-07-6 | MFCD00077857 | ≥98.0% | 352.47 g/mol | C20H32O5 | 5 MG
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Prostaglandin D2 (PGD2) is an endogenous prostaglandin involved in sleep regulation, inflammatory signaling, and mast cell responses. This product is supplied as a research-grade solid in a 5 mg quantity and is intended for biochemical and pharmacological studies. Not for human or veterinary use.
- Endogenous prostaglandin involved in sleep and inflammatory pathways.
- High purity, ≥98.0% by vendor specification.
- Molecular weight 352.47 g/mol and formula C20H32O5.
- Supplied as a 5 mg solid vial for laboratory use.
- Store protected from moisture and light at -20°C or colder for long-term stability.
- Intended for research use only.
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Quality Biological Inc Amphotericin B/Pen/Strep Mix 50ML, (120-096-711EA) QBICF0079
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Amphotericin B 250 ¿g/ml/Penicillin10,000 Units/ml/ Streptomycin 10,000 ¿g/ml, prepared with cell culture grade water, 0.1micron filtered and cytotoxicity tested
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