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Indole-3-butyric acid (IBA)Synonym: 4-(3-Indolyl)butanoic acidSynthetic AuxinPlant tissue culture testedAppearance: white to light tan powderMelting Point: 124.0-125.5 °CSoluble in ethanol or 1N NaOH
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The OHpak LB-806 is a high-performance, polymer-based packed column designed for aqueous Size Exclusion Chromatography (SEC) and Gel Filtration Chromatography (GFC). This robust column excels in applications utilizing light scattering detectors, thanks to its controlled low bleeding. It is compatible with versatile eluents, including N,N-Dimethylformamide (DMF) for polar polymers and meets USP-NF L38 and L39 requirements for regulated methods.
Aqueous SEC/GFC analysis for water-soluble macromolecules.
MALS compatibility with low column bleeding for sensitive detectors.
Can utilize DMF as an eluent for polar polymer analysis.
Fulfills USP-NF L38 and L39 requirements.
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Intrinsic Factor from Porcine Gastric Mucosa (0 1 mg) consists of the natural binder and transporter of Vitamin B12 purified from the porcine gastric mucosa This product has been used as a molecular tool in Vitamin B12 detection This is supplied as a solution For in vitro research use only
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Use granulocyte-macrophage colony-stimulating factor (GM-CSF) to induce the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils eosinophils and macrophages (Barreda et al. Dev Comp Immunol 2004). Recombinant human GM-CSF also promotes the production of myeloid cells of the granulocytic and monocytic lineages in vivo. It has been tested for mobilization of hematopoietic progenitor cells and for treating chemotherapy-induced neutropenia in patients. In combination with other cytokines such as stem cell factor IL-3 erythropoietin and thrombopoietin GM-CSF also stimulates erythroid and megakaryocyte progenitor cells (Barreda et al.). Human recombinant GM-CSF from STEMCELL comes lyophilized with ≥ 95% purity EC50 200 pg/mL endotoxin levels verified 1.0 EU/μg protein. Alternative names Colony-stimulating factor 2 CSF-2 MGI-1GM Pluripoitin-alpha. Visit STE
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Epidermal growth factor (EGF) is characterized by high-affinity binding to various EGF receptors (EGFRs) and the production of mitogenic responses (Carpenter Cohen). EGF promotes EGFR dimerization resulting in activation of downstream pathways including PI3K ERK1/2 JAK/STAT -catenin and calcium signaling. EGF is secreted by the gut-associated salivary and Brunner’s glands is found in a variety of body fluids and stimulates cell proliferation and differentiation in rodent and neonatal human intestine (Wright et al.). Central nervous system stem cells also proliferate in response to the EGF stimulus (Reynolds Weiss). This product is animal component-free.
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PromoCell Renal Epithelial Cell Growth Medium 2 is an optimized low-serum (5% V/V) medium that additionally contains Epinephrine. The combination of low serum and selected growth factors ensures successful growth in vitro making the Renal Epithelial Cell Growth Medium 2 the first choice for PromoCell Renal Epithelial Cells.Although all PromoCell media are optimized for use with primary human cells, we have received feedback from customers that this particular medium can also be used for porcine and mouse renal epithelial cells.| Media supplement | Final supplement concentration|| Fetal Calf Serum | 0.05 ml / ml || Epidermal Growth Factor (recombinant human) | 10 ng / ml || Insulin (recombinant human) | 5 μg / ml || Hydrocortisone | 36 ng / ml || Epinephrine | 0.5 μg / ml || Triiodo-L-thyronine | 4 pg / ml || Transferrin (recombinant human) | 5 μg / ml |
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Tgfb1 (transforming growth factor-1 human) is a 25kDa peptide encoded by the gene mapped to human chromosome 19q13.2. TGf-1 polypeptide is produced as a precursor with hydrophobic signal sequence pro-region and mature peptide. Cleavage of the precursor at tetrabasic cleavage site results in monomers of carboxy-terminal 112 amino acids. The biologically active form of Tgfb1 exists as a disulphide-linked homodimer. In mammals three isoforms of TGf- has been identified TGf-1 TGf-2 and TGf-3.
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Recombinant human RAB1B protein expressed in HEK293 cells and produced as an Fc fusion. Supplied as a purified research-grade protein in microgram quantities for use in biochemical assays, binding studies, and antibody validation. Store and handle according to the supplier datasheet.
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Epidermal growth factor receptor (EGfR) belongs to a family of cell surface receptors called receptor tyrosine kinases (RTKs) and is also the most studied member of this family. It is made up of an ectodomain (ECD) which contains four subdomains called DI-DIV a transmembrane region and a cytoplasmic tyrosine kinase domain (TKD). Binding of the ligand induces conformational changes in the ECD which leads to the dimerization of EGfR. This results in the activation of the TKD and the subsequent signal transduction. This receptor has a molecular weight of A¼178kDa.
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