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MW 212.33 g/mol, Purity >97%. Alpha, beta unsaturated fatty acid. Diffusible signal factor (DSF) in extracellular microbial and fungal communication systems. Cell-cell communication signal involved in the synchronization of virulence gene expression and biofilm dispersal of the pathogen Xanthomonas campestris pv. campestris (Xcc).
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CD40 protein is a TNFSF5/CD40LG receptor that transduces signals through TRAF6 and MAP3K8-mediated pathways activates ERK in macrophages and B cells and induces immunoglobulin secretion CD40 exists as monomers and homodimers and interacts with TRAF proteins (TRAF1 TRAF2 TRAF3 TRAF5 and TRAF6) CD40 Protein Human (HEK293 Fc) is the recombinant human-derived CD40 protein expressed by HEK293 with C-hFc labeled tag
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IFN-lambda 1 (IL-29) is a member of the Type-III interferon family IFN-lambda 1 signals through a heterodimeric receptor complex comprising IFN receptor 1 (IFNLR1) and IL-10 receptor subunit- (IL-10RB) When IFN-lambda 1 binds with the receptor complex Jak1 and Tyk2 will be activated and leads to subsequent tyrosine phosphorylation of the IFN- R1 and activation of STAT1 and STAT2[1] IFN-lambda 1 modulates immunity in infections and autoimmune diseases[2] IFN-lambda 1/IL-29 Protein Human (HEK293 His) is a recombinant human IFN-lambda 1 (G20-T200) with C-terminal 10 His tag which is produced in HEK293
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RSPO1/R-spondin-1 is a secreted glycoprotein RSPO1/R-spondin-1 binds to LGR4/5/6 receptors and ZNRF3/E3 ubiquitin ligases inhibits Wnt receptor degradation stabilizes -catenin and promotes its nuclear translocation and activates target gene transcription RSPO1/R-spondin-1 Human promotes intestinal organoid survival induces pancreatic -cell proliferation to improve diabetes enhances osteogenic differentiation of mesenchymal stem cells to treat osteoporosis and inhibits bone erosion in arthritis models RSPO1/R-spondin-1 Protein Human (HEK293 His) is a recombinant RSPO1/R-spondin-1 protein expressed by HEK293 with a C-His tag
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MME proteins exhibit thermolysin-like specificity and primarily degrade polypeptides of up to 30 amino acids Crucially it plays a key role in cleaving the Gly-Phe bond to degrade opioid peptides including Met-enkephalin and Leu-enkephalin MME Protein Human (HEK293) is the recombinant human-derived MME protein expressed by HEK293 with tag free
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MMP-8 also known as matrix metalloproteinase-8 or collagenase-2 is recognized for its enzymatic abilities particularly its ability to break down fibrillar types I II and III collagen This enzymatic activity suggests that MMP-8 plays an important role in the remodeling and turnover of collagen-rich tissues such as connective tissue cartilage and bone MMP-8 Protein Human (HEK293 His) is the recombinant human-derived MMP-8 protein expressed by HEK293 with C-10 His labeled tag
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The CD6 protein is a cell adhesion molecule that mediates cell-cell contacts and regulates T cell responses through interaction with ALCAM/CD166 It functions as a costimulatory molecule promoting T cell activation proliferation and contributing to the formation of immune synapses CD6 Protein Human (HEK293 Fc) is the recombinant human-derived CD6 protein expressed by HEK293 with C-hFc labeled tag
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Epidermal growth factor (EGf) is synthesized in Henle loop and the distal convoluted tubule in the kidney. It is also produced in salivary glands and duodenum.
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BDNf is a member of the neurotrophin family of growth factors that includes NGf NT-3 and NT-4. All neurotrophins have six conserved cysteine residues and share a 55% sequence identity at the amino acid level. BDNf has been shown to enhance the survival and differentiation of several classes of neurons in vitro including neural crest and placode-derived sensory neurons dopaminergic neurons in the substantia nigra basal forebrain cholinergic neurons hippocampal neurons and retinal ganglial cells.1 BDNf is expressed within peripheral ganglia and is not restricted to neuronal target fields raising the possibility that BDNf has paracrine or even autocrine actions on neurons as well as non-neuronal cells.The active form of BDNf recombinant human protein (27 kDa) is a dimer formed by two identical 119 amino acid subunits held together by strong hydrophobic interactions
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Recombinant human hepatocyte growth factor (HGf) is produced from the 728 amino acid residue variant of the human pre-pro-HGf protein 6 and expressed in a mouse myeloma cell line NSO.The HGf gene is mapped to human chromosome 7q21.1. The encoded protein is a mesenchymal-fibroblast derived cytokine.
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