Phosphoenolpyruvate carboxykinase 2 (PCK2) is an enzyme crucial for glucose metabolism, catalyzing the rate-limiting step in converting oxaloacetate (OAA) to phosphoenolpyruvate (PEP). This metabolic pathway is vital for glucose synthesis from lactate and other citric acid cycle precursors. PCK2's activity supports gluconeogenesis, maintaining glucose homeostasis during fasting or high energy demand. By converting OAA to PEP, PCK2 facilitates glucose generation, essential for providing energy to tissues like the brain and red blood cells, thus highlighting its importance in cellular energy balance.
- Supplied as a 0.22 μm filtered solution
- Endotoxin level less than 1 EU/μg
- Stable for 1 year at -80°C, 3 months at -20°C after opening
- Ships with dry ice
- Purity 94.3% by reducing SDS-PAGE