General Cell Lines and Cell Cultures
Genscript Corporation CHO-K1/CD64 Stable Cell Line
Recombinant CHO-K1 cells stably overexpress high affinity human Fc fragment of IgG receptor Ia (Fc RI CD64) on the cell surface containing one alpha chain and two gamma chains The surface expression of CD64 is validated by FACS analysis This stable cell line product is designed for measuring the binding affinity and stability of the Fc region of antibodies Fc fusion proteins or antibody based biologics that bind with CD64 during biologics research and development
ATCC Quantitative Genomic; RNA from Sendai virus; Strain: Cantell
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load.
Eurofins Discoverx ChemiScreen AT1 Angiotesin Receptor Stable Cell Line, 2 vials. (HTS064C)
The ChemiScreen AT1 Angiotensin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. Angiotensin-II) based activation of AGTR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses AGTR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of AGTR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Genscript Corporation CHO-K1/BDCA2 and FcER1G Stable
Recombinant CHO-K1 cells stably overexpress human C-type lectin domain family 4 member C (BDCA2) and Fc epsilon receptor Ig (FcER1G) on the surface The surface expression of BDCA2 is validated by FACS analysis
Biochain Institute Inc Colon Tumor Tissue Array - 64 Different Colon tumors. Plus positive control and negative control, 5 slides/PK
BioChain's tissue arrays or tissue microarrays (TMAs) are a useful tool in biomarker research and drug target validation. It consists of paraffin blocks that are assembled in array fashion to allow multiplex histological analysis. BioChain's TMAs provide a valuable tool for analysis of protein, RNA, or DNA molecules in oncology, both the malignant and metastatic markers. TMAs can also be constructed with tissues from other diseases and species.
Lonza Walkersville Transfection Transfection Kit 1/PK
The P4 Primary Cell 384-well Nucleofector Kit is one of our five kits suited for high-throughput transfection of primary cells when working with the 384-well HT Nucleofector System This kit has been determined to be optimal for transfecting following cell types B cell (mouse) DC (mouse) immat MEF (mouse) The respective cell type-specific Optimized Protocols or recommendations are available under Instructions or in our Lonza Bioscience knowledge database In these Optimized Protocols the best Nucleofection conditions are indicated In addition we share our experience and knowledge for treatment of individual cell types The kit is available in different variants for either 2 x 384 or 10 x 384 reactions
Eurofins Discoverx InCELL Hunter A549 SIK1 Kinase Binding Cell Line, 2 vials. (96-0051C15)
The InCELL Hunter A549 SIK1 Kinase Binding Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with kinases. This cell line enables assessment of compound-engagement-based stabilization of SIK1 via detection of SIK1 levels. This product uses EFC technology. The cell line included overexpresses SIK1 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is denatured by the heat treatment and no EFC signal is produced. When compound engages and heat-stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Phymatotrichopsis omnivora; 513
An ampoule containing viable cells suspended in cryoprotectant.
ATCC Human rhinovirus 1A; Strain: 2060
Human rhinovirus 1A strain 2060 is propagated in H1HeLa cells (ATCC CRL-1958). This strain was isolated from the naso-pharyngeal washings of a patient with mild respiratory illness in Ohio and was deposited by the National Institute of Allergy and Infectious Diseases (NIAID). It has applications in respiratory disease research.
Eurofins Discoverx PathHunter CHO-K1 BAI2 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0546C2)
The PathHunter BAI2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of BAI2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged BAI2 and EA-tagged β-Arrestin-2. Activation of BAI2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Clostridium saccharoperbutylacetonicum; Strain N1-4 (HMT) N
Type strain. Derived from ATCC 13564.