General Cell Lines and Cell Cultures
Eurofins Discoverx PrecisION hASIC3 Recombinant Stable Cell Line, 2 vials. (CYL3055)
The PrecisION hASIC3 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying ASIC3 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses ASIC3 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Eurofins Discoverx PrecisION hnAChR α7/ric3 Recombinant Stable Cell Line, 2 vials. (CYL3097)
The PrecisION hnAChR α7/ric3 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying nAChR α7/ric3 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses nAChR α7/ric3 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Eurofins Discoverx ChemiScreen SST3 Somatostatin Receptor Stable Cell Line, 2 vials. (HTS171C)
The ChemiScreen SST3 Somatostatin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. somatostatin) based activation of SSTR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses SSTR3 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of SSTR3, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay GLP-2 Receptor Frozen Cells, 2 Vials of Cells. (HTS164RTA)
The Ready-to-Assay GLP-2 Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. GLP-2) based activation of GLP2R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GLP2R alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of GLP2R, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen OXGR1 α-Ketoglutarate Receptor Stable Cell Line, 2 vials. (HTS191C)
The ChemiScreen OXGR1 α-Ketoglutarate Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. α-ketoglutarate) based activation of OXGR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses OXGR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of OXGR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay GPR103/Peptide P518 Receptor Frozen Cells, 2 Vials of Cells. (HTS189RTA)
The Ready-to-Assay GPR103/Peptide P518 Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. QRFP neuropeptides) based activation of QRFPR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses QRFPR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of QRFPR, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Pfizer Pneumococcal; polysaccharide powder; Type 66 (35B) 10mg
Purified pneumococcal polysaccharide type 35B is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 35B can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
ATCC Staphylococcus epidermidis
Staphylococcus epidermidis strain 597 is a drug-resistant bacterium that was isolated in 1997 from the blood of a 70-year-old male neurology patient with bacteremia.
ATCC Trichophyton equinum
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC U-CHCF359B; Chordoma; Human (Homo sapiens)
U-CHCF359B (ATCC CRL-3517) is a cell line established from clival tumor material of the chordoma xenograft model CF359.
Eurofins Discoverx ChemiScreen NK3 Tachykinin Receptor Stable Cell Line, 2 vials. (HTS190C)
The ChemiScreen NK3 Tachykinin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. tachykinins) based activation of TACR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TACR3 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of TACR3, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay CALCRL Calcitonin Receptor Frozen Cells, 2 Vials of Cells. (HTS172RTA)
The Ready-to-Assay CALCRL Calcitonin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. parathyroid hormone) based activation of CALCRL GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CALCRL (and modulating protein RAMP1) alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of CALCRL, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.