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Cayman Chemical 4MethyLMbelIferyl2ACTAm 100mg
A fluorogenic substrate for β-hexosaminidases; is cleaved by β-hexosaminidases to release the fluorescent moiety 4-ΜU; ex = 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively; em = 445 to 455 nm, increasing as pH decreases; has been used to quantify β-hexosaminidase activity in serum or leukocytes from patients with GM2 gangliosidoses such as Tay-Sachs disease
Cayman Chemical Mn III ProtprphyrIn I Chl 50mg
A metalloporphyrin; induces mRNA expression of the genes encoding δ-aminolevulinate synthase and HO in chick embryo liver cells at 10 µM; manganese(III) protoporphyrin IX chloride-containing nanobialys have been used in MRI of fibrin clots in vitro; has been used in the synthesis of MnGGH
Cayman Chemical MonbromobImn 50mg
A thiol-reactive fluorogenic probe; used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides
Cayman Chemical DIhomoLInolenIc AcId 100mg
An elongation product of γ-linolenic acid (18:3), rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4); metabolized through the cyclooxygenase pathway to produce 1-series prostaglandins; can reduce atopic dermatitis and atherosclerosis when added to the diet of mice
Cayman Chemical Daclatsvr 50mg
An NS5A inhibitor (Kds = 8 and 210 nM for the NS5A33-202 and NS5A26-202 residues of HCV genotype 1b, respectively); potently inhibits HCV replication in multiple HCV replicon genotypes (EC50s = 9-146 pM) with the highest potency in genotypes 1b and 4a (EC50s = 9 and 12 pM, respectively); disrupts NS5A subcellular localization when used at a concentration of 1 nM; inhibits HCV RNA synthesis and virion assembly and secretion when used at a concentration of 1 nM; inhibits OAT1B1 and OAT1B3 (IC50s = 1.5 and 3.27 µM, respectively)
Cayman Chemical BS-181hydrochlorIde 50mg
A selective Cdk7 inhibitor that blocks the activity of Cdk-activating kinase (IC50 = 21 nM); inhibits the growth of cancer cell lines in vitro and MCF-7 human xenografts in nude mice
Cayman Chemical DapoxetInhydrochlorIde 50mg
An analytical reference standard categorized as an SSRI; intended for research and forensic applications
Cayman Chemical AcetylDLcarnItInchlorIde 100mg
A racemic mixture of acetyl-D-carnitine and acetyl-L-carnitine; increases the oxidation rate of the branched-chain 2-oxo acid 3-methyl-2-butanoate in isolated rat muscle mitochondria in the absence of carnitine at 1 mM; decreases the hind limb vasculature blood flow rate in rats; decreases the levels of palmitic acid and oleic acid in the cerebral cortex during the recovery period in a dog model of insulin-induced hypoglycemic brain injury
Cayman Chemical 6methoxy Naphthalen ACtIc 50mg
6-MNA is a competitive, non-selective COX inhibitor.{1286,1364,1791} The Ki values for ovine COX-1 and -2 are 21 and 19 µM, respectively.{1364} The IC50 values are 70 and 20 µM for human recombinant COX-1 and -2, respectively.{1286}
Cayman Chemical SB-258585hydrochlorIde 50mg
A potent, selective antagonist of the serotonin 5-HT6 receptor (pKi = 8.53); has been used in cells and in animals
Cayman Chemical olyloyethyl phsphorylchol 50mg
Oleyloxyethyl phosphorylcholine is an inhibitor of PLA2 with an IC50 value of 6.2 µM for porcine pancreatic PLA2.{879}
Cayman Chemical 1H 1H 2H 2HPRfluorodecnsu 50mg
A polyfluoroalkyl substance; has been found as a contaminant in sea and river water
Cayman Chemical Z3Dodecenyl E2butenoAT 100mg
A female sex pheromone produced by the sweet potato weevil