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Cayman Chemical 3-AcetylpyrIdIn NAD 50mg
A NAD analog; used to study the mechanisms of oxidative phosphorylation
Cayman Chemical sorentn 50mg
A flavonoid with diverse biological activities; induces apoptosis in and reduces cell viability of PATU-8988 and PANC-1 pancreatic cancer cells; reduces expression of COX-2, IL-6, 5-LO, and TNF-α in RAW 264.7 cells; reduces carrageenan-induced paw edema and air pouch blood vessel swelling in mice at 20 mg/kg; increases stomach levels of SOD and GSH and reduces ulcer area in a rat model of indomethacin-induced gastric ulcers
Cayman Chemical Galantamine 50mg
An alkaloid with AChE inhibitory and nAChR potentiating activities; selectively inhibits AChE over BChE (IC50s = 636 and 8,404 nM, respectively); potentiates ACh-induced currents in HEK293 cells expressing human α4β2 subunit-containing nAChRs at 0.5 µM; decreases escape latency and path length in the Morris water maze in the APP23 transgenic mouse model of Alzheimer’s disease at 1.3 mg/kg per day
Cayman Chemical 14-nhydrodIgItoxIgenIn 50mg
A cardenolide; reduces the activity of guinea pig heart Na+/K+-ATPase by 15% at 10 µM
Cayman Chemical RosIglItazon 100mg
A PPARγ agonist; activates PPARγ1 and PPARγ2 in reporter assays (EC50s = 30 and 100 nM, respectively); selectively activates chimeras containing the LBDs of PPARγ over PPARα and PPARδ in a cell-based reporter assay at 10 mM; an inhibitor of ACSL4 (IC50 = 0.5 µM), inhibits RSL3-induced ferroptosis in Pfa1 cells and Pparg KO cells, and increases survival in a Gpx4 KO mouse model of ferroptosis at 0.0125 mg/ml in the drinking water; decreases HbA1c and fasting blood glucose levels in a rat model of type 2 diabetes induced by STZ and a high-carbohydrate and high-fat diet at 4 mg/kg
Cayman Chemical 4mthylaPyrroldInobutIoph 50mg
A synthetic cathinone with psychoactive properties which has recently been identified in party pills and powders; intended for forensic and research applications
Cayman Chemical Fluorometholon 50mg
A synthetic glucocorticoid that binds to glucocorticoid receptors (IC50 = 1.5 nM; Kd = 2.8 nM); decreases survival of cultured corneal epithelial cells and inhibits their migration in a scratch assay following 12 hours of treatment (0.01%)
Cayman Chemical on-4059hydrochlorIde 50mg
A BTK inhibitor (IC50 = 2.2 nM); selective for BTK over LCK, LYN, and Fyn at 1 µM; inhibits B cell proliferation and activation in vitro and reduces tumor growth in a TMD8 mouse xenograft model
Cayman Chemical GInkgonlIc AcId 100mg
An anacardic acid with diverse biological activities; inhibits GPDH (IC50 = 3 μg/ml); inhibits PI3Kδ (IC50 = 2.49 μM) and IgE-mediated RBL-2H3 mast cell degranulation in vitro (IC50 = 2.4 μM); reduces S. mutans biofilm formation (MBIC50 = 4 μg/ml)
Sigma Aldrich Fine Chemicals Biosciences Human Serum CRP ERMR certi1EA
Certified for C-reactive protein (CRP) in human serum. ERM-DA474IfCC cert ERM-DA474IfCC reportERM-DA474IfCC origin
Cayman Chemical EIcosapentaeNIc ACD mthyl 50mg
An esterified form of EPA; has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils
Cayman Chemical Cndesartn 100mg
An AT1 receptor antagonist (Kis = 0.17, 0.12, and 0.12 nM for human AT1, rat AT1A, and rat AT1B recombinant receptors, respectively); selective for AT1 over AT2 receptors (Ki = 26,500 nM for the recombinant human AT2 receptor); inhibits angiotensin II-induced contraction of isolated rabbit aortic strips and increases in blood pressure in rats (ID50 = 0.033 mg/kg, i.v.)
Cayman Chemical DehydroascorbIc AcId 100mg
An oxidized form of ascorbic acid; inhibits hydrogen peroxide-induced cell death in murine astrocytes by approximately 74 and 83% at 0.5 and 1 mM, respectively; increases GPX and glutathione reductase activity and inhibits ROS production in hydrogen peroxide-treated astrocytes at 1 mM; increases cerebral blood flow and reduces infarct volume and mortality in a mouse model of cerebral ischemia-reperfusion injury induced by transient MCAO when administered prior to ischemia at 40 and 250 mg/kg; reduces infarct volume in a permanent MCAO mouse model when administered pre- or post-ischemia at 250 and 500 mg/kg, respectively
Cayman Chemical Arnba euchroma Shkalkn 50mg
A naphthoquinone and racemic mixture of alkannin and shikonin