Sera
Cayman Chemical DeoxypodophylotoxIn 100mg
A flavolignan with diverse biological activities; inhibits tubulin polymerization in a cell-free assay at 50 nM; inhibits COX-2 and 5-LO in isolated mouse bone marrow-derived mast cells stimulated with KL, IL-10, and LPS (IC50s = 1.89 and 0.37 µM, respectively); reduces viral yield in the supernatant of HSV-1- or HSV-2-infected MRC-5 cells at 0.02 UG/ml; inhibits aggregation of rabbit platelets induced by PAF, collagen, or arachidonic acid; induces mortality in P. rapae fifth instar larvae (LC50 = 0.02 g/L); reduces tumor growth in a CT26 murine colon cancer model at 70 UG/kg
Cayman Chemical LysophosphatIdylcholIn 50mg
A mixture of lysophosphatidylcholines isolated from egg; a major phospholipid component of oxidized low-density lipoprotein (ox-LDL), and it accumulates in animal models of atherosclerosis; pro-inflammatory; released from apoptosis cells in vitro and and acts as a chemoattractant for monocytes; induces demyelination of axons in vivo in rats (2 µl, 1%)
Cayman Chemical NonoIc AcId 100mg
A medium-chain saturated fatty acid; a volatile compound that has been found in raw and roasted pecans; inhibits mycelial growth and spore germination in the plant pathogenic fungi M. roreri and C. perniciosa in a concentration-dependent manner; has herbicidal activity against a variety of species, including crabgrass; has been used as an internal standard for the quantification of free fatty acids in olive mill waste waters
Cayman Chemical ClothInIdIn 50mg
A neonicotinoid insecticide and an active metabolite of thiamethoxam; binds to nAChRs (IC50 = 0.6 nM for housefly head membranes); activates non-desensitizing nAChRs in cockroach neurons in vitro (IC50 = 1,520 nM); induces mortality in adult M. persicae (LC95 = 1.28 mg/L), as well as H. virescens and S. frugiperda second instar larvae at 8 mg/L in a leaf-dip bioassay; increases the number of premature births in rabbits at >25 mg/kg; reduces the length and weight of fathead minnows when administered in tank water at 20 mg/L
Cayman Chemical Betamethason DIpropIonAT 100mg
A synthetic corticosteroid and prodrug from of betamethasone; binds to the glucocorticoid receptor (IC50 = 5.25 nM); decreases the number of circulating eosinophils in dogs; reduces croton oil-induced exudate formation in a granuloma pouch assay in rats
Bio IVT Human AB Serum, Off-the-Clot, Heat Inactivated, 20 mL, 50 mL, 100 mL
Human AB Serum, Off-the-Clot, Heat Inactivated, 20 mL, 50 mL, 100 mL
Cayman Chemical Montelukast 50mg
A CysLT1 receptor antagonist (IC50 = 4.9 nM in HEK293 cell membranes expressing the human receptor); selective for CysLT1 over CysLT2 receptors (IC50 = >10,000 nM in COS-7 cell membranes expressing the human receptor); inhibits LTD4-induced bronchoconstriction in anesthetized guinea pigs (ED50 = 69 nmol/kg, p.o.); inhibits ovalbumin-induced airway hyperresponsiveness and increases in the number of total cells and eosinophils in BALF in a mouse model of allergic asthma at 3 and 10 mg/kg
Cayman Chemical TrIacetylphloroglucInol 100mg
A bridging ligand; has been used in the synthesis of various compounds
Cayman Chemical PhysostIgmInsalIcylate 50mg
An alkaloid and cholinergic agent; inhibits AChE (IC50 = 0.67 nM); inhibits ChE and increases vagal stimulation-induced ACh output in isolated chicken heart at 10 µM; induces decentralized lower eyelid contractions and increases blood pressure in anesthetized rats at 200 and 400 UG/kg
Cayman Chemical Sulpho Nonate 100mg
Sulpho NONOate produces nitrous oxide but no NO at physiological pH. Therefore, this compound may be used as a negative control in experiments using other NO donors of the NONOate class.{875,5437}
Cayman Chemical Oxyresveratrol 50mg
A resveratrol analog; scavenges H2O2 and NO (IC50 = 45.3 μM) and DPPH (IC50 = 28.9 μM); reduces brain infarct volume and reduces cytochrome c release and caspase-3 activation in an in vivo model of stroke at 10 mg/kg; inhibits tyrosinase activity (IC50s = 1.2 and 52.7 μM in mushroom and mouse melanoma B-16 cells, respectively)
Cayman Chemical 4-O-Methylresveratrol 50mg
A stilbene with diverse biological activities; inhibits growth of A549, SKOV3, SK-MEL-2, XF498, and HCT15 cancer cells (IC50s = 3.8, 5.7, 3.2, 5.6, and 6.7 UG/ml, respectively); inhibits arachidonic acid- or collagen-induced rabbit platelet aggregation from 0.05-0.2 mM; scavenges free radicals in a TEAC assay; suppresses RANKL-induced osteoclastic differentiation of murine BMDMs; reduces LPS-induced bone loss in mice at 50 mg/kg
Cayman Chemical PropIverInhydrochlorIde 100mg
A muscarinic acetylcholine receptor antagonist; binds to M1 and M2 mAChRs in rat bladder and submaxillary gland, respectively (Kis = 0.3 and 0.19 µM, respectively); inhibits carbachol-induced contraction of bladder strips isolated from patients with normal bladder activity and detrusor overactivity associated with benign prostatic hyperplasia (pA2s = 7.7 and 7.6, respectively)
Cayman Chemical Lnnamvr 50mg
An inhibitor of influenza neuraminidases and an active metabolite of laninamivir octanoate; inhibits the neuraminidases from influenza A H1N1, H2N2, and H3N2 strains (mean IC50s = 2.49, 11.4, and 16.7 nM, respectively) and influenza B Victoria and Yamagata strains (mean IC50s = 18.9 nM for both); increases survival in a mouse model of lethal influenza H1N1 infection when administered intranasally at 69 UG/kg