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Cayman Chemical Adrenic Acid, Purity: ≥98%, CAS: 28874-58-0, 100 mg
A naturally occurring PUFA formed through a 2-carbon chain elongation of arachidonic acid; present in the adrenal glands, brain, testis, and kidney
Cayman Chemical 2 3MehylendIoxy PyrovalRo 50mg
A potential psychoactive designer drug structurally related to 3,4-MDPV; intended for forensic purposes
Cayman Chemical SotalolhydrochlorIde 50mg
A β-AR antagonist (IC50s = 8.9 and 5.2 μM for β1- and β2-ARs, respectively) and a class III antiarrhythmic agent; decreases IK in guinea pig ventricular cells and prolongs action potential duration in electrically stimulated isolated guinea pig papillary muscles at 100 μM; decreases heart rate and increases blood pressure and the cardiac FRP in a canine model of PES-induced ventricular tachycardia
Cayman Chemical C4 Ceramide (d18:1/4:0), Purity: ≥95%, CAS: 74713-58-9, 50 mg
A bioactive sphingolipid; inhibits IL-4 production by 16% in PMA-stimulated EL4 T cells at 10 μM; cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively); increases maturation and stability of F508del-CFTR proteins, enhances cAMP-activated chloride secretion, and suppresses secretion of IL-8 in primary epithelial cells isolated from patients with cystic fibrosis
Cayman Chemical Monodansylcadaverine, Purity: ≥95%, CAS: 10121-91-2, 100 mg
A fluorescent marker for autophagic vacuoles; autofluorescent substance incorporated into multilamellar bodies by both an ion trapping mechanism and interaction with membrane lipids; exhibits Stokes shift and increased relative fluorescence in hydrophobic environments; selectively accumulates in PaTu 8902 subcellular fractions containing the lysosomal enzymes acid phosphatase and cathepsin D, but not those containing the rough and smooth endoplasmic reticulum markers TRAM and cytochrome P450, respectively
Cayman Chemical Hexanoyl Glycine, Purity: ≥95%, CAS: 24003-67-6, 50 mg
An acylated amino acid that is used as a urinary biomarker for several indications; increased urinary excretion is indicative of MCAD deficiency; can also be used as a biomarker for exposure to gamma radiation
Cayman Chemical Nortriptyline (hydrochloride), Purity: ≥98%, CAS: 894-71-3, 100 mg
A tricyclic antidepressant that blocks norepinephrine and serotonin transporters (KDs = 4.4 and 18 nM, respectively) more potently than the dopamine transporter (KD = 1.1 µM)
Cayman Chemical Guanethidine (sulfate), Purity: ≥95%, CAS: 645-43-2, 100 mg
A peripherally acting, antihypertensive compound that competes with norepinephrine for transport into presynaptic terminals of adrenergic neurons by the norepinephrine transporter, reducing the release of norepinephrine in response to action potentials
Cayman Chemical MInocyclInhydrochLRIde hy 50mg
A broad-spectrum tetracycline antibiotic; active against E. faecium in vitro (MIC = 16 mg/L); reduces the number of bacteria in the lung in a mouse model of multi-drug resistant A. baumannii-induced pneumonia at 20 mg/kg every 12 hours; reduces spinal cord lesion size and improves hindlimb function post-injury in a mouse model of acute spinal cord injury at an initial dose of 50 mg/kg and subsequent doses of 25 mg/kg per day for 5 days
Cayman Chemical Desmethylene Paroxetine (hydrochloride), Purity: ≥98%, CAS: 1394861-12-1, 50 mg
A major urinary metabolite of the selective serotonin reuptake inhibitor paroxetine; may be used as a control in LC/MS or GC/MS paroxetine testing applications
Cayman Chemical 5-Cyano-2,3-di-(p-tolyl)tetrazolium (chloride), CAS: 90217-02-0, 100 mg
A redox-sensitive tetrazolium salt used primarily to detect metabolic activity in microorganisms; readily taken up by living cells and reduced by respiratory activity to produce a red fluorescent, water-insoluble formazan crystal (absorption maximum at 450 nm)
Cayman Chemical Pinacidil (hydrate), Purity: ≥95%, CAS: 85371-64-8, 100 mg
A potassium channel opener, activating the ATP-modulated potassium channels of guinea pig bladder and heart with Ki values of 104 and 251 nM, respectively; completely relaxes coronary artery rings preconstricted with serotonin (IC50 = 1.26 µM)
Cayman Chemical 4-methoxy-α-Pyrrolidinobutiophenone (hydrochloride), Purity: ≥98%, CAS: 2749897-35-4, 50 mg
A pyrovalerone analog that shares structural features with 4-MeO-α-PVP and 4-MePBP; intended only for forensic and research applications
Cayman Chemical Pinacidil (hydrate), Purity: ≥95%, CAS: 85371-64-8, 50 mg
A potassium channel opener, activating the ATP-modulated potassium channels of guinea pig bladder and heart with Ki values of 104 and 251 nM, respectively; completely relaxes coronary artery rings preconstricted with serotonin (IC50 = 1.26 µM)
Cayman Chemical Bucladesine (sodium salt), Purity: ≥95%, CAS: 16980-89-5, 100 mg
A cell-permeable, cyclic nucleotide derivative that mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor