Human Sera
Cayman Chemical UTPsodIum salt 100mg
An anticancer agent decreases the viability of LN-229 glioblastoma cells (IC50 1.17 UM) crosses the blood-brain barrier in a temozolomide-resistant orthotopic PDX mouse model of glioblastoma
Cayman Chemical Valeroyl SalIcylate 100mg
An ionizable cationic lipid (pKa 6.4) has been used in the generation of LNPs for the delivery of mRNA in vitro and in vivo LNPs containing E12CA1A3 and encapsulating an mRNA reporter induce luciferase reporter expression in mouse BMDCs and mice LNPs containing E12CA1A3 are cleared more rapidly from the liver than LNPs containing DLin-MC3-DMA in mice
Cayman Chemical Butenoyl PAF 50mg
An internal standard for the quantification of phosmet by GC- or LC-MS
Cayman Chemical PCMPAhydrochlorIde 50mg
An antibiotic active against a variety of bacteria including S. aureus B. anthracis B. subtilis E. coli and P. aerUGinosa (MICs 100 6.25 100 50 and 25 UG/ml respectively)
Cayman Chemical TIplaxtInIn 50mg
A derivative of thalidomide inhibits the proliferation of EA.hy926 endothelial cells (IC50 200 UM) an intermediate in the synthesis of a PROTAC c-MET degrader with antiproliferative activity in c-MET-sensitive cancer cells an intermediate in the synthesis of a thalidomide derivative that reduces clinical scores in a mouse model of EAE
Cayman Chemical ParthenolIde 50mg
An internal standard for the quantification of thiacloprid by GC- or LC-MS
Cayman Chemical TroglItazon 100mg
An inhibitor of Wnt signaling inhibits CHIR99021-induced Wnt signaling in a reporter assay using BEAS-2B cells at 100 nM induces differentiation of and decreases CHIR99021-induced hyperproliferation of and nuclear phosphorylation ofBcatenin in isolated mouse ABSCs at 1 UM
Cayman Chemical Serum Iron asy KIt 192Wel
An antibiotic active against S. aureus methicillin-resistant S. aureus (MRSA) and B. subtilis (MICs 2 4 and 2 UG/ml respectively) without inducing cytotoxicity in HepG2 HSkMC or IMR-90 cells at 10 UM active against 40 antibiotic-resistant clinical isolates (median MICs 2-16 UG/ml) decreases MRSA viral titers in the skin in a neutropenic mouse wound infection model when applied topically at 1 (w/w) reduces MRSA viral titers in the thigh in a neutropenic mouse thigh infection model at 80 mg/kg i.p.
Cayman Chemical 2MethoxymethcathInonhydro 50mg
A fluorogenic substrate for chymotrypsin and chymotrypsin-like proteases AMC is released upon enzymatic cleavage by proteases and its fluorescence can be used to quantify protease activity ex/em 340-360/440-460 nm respectively
Cayman Chemical 4FluoromethamphetamInhydr 50mg
A peptide MC1R agonist selectively induces cAMP production in HEK293 cells expressing recombinant human MC1R over those expressing recombinant human MC3R MC4R or MC5R (EC50s 3 902 915 and >1000 nM respectively)
Cayman Chemical DETA Nonate 100mg
An inhibitor of Wnt signaling inhibits CHIR99021-induced Wnt signaling in a reporter assay using BEAS-2B cells at 100 nM induces differentiation of and decreases CHIR99021-induced hyperproliferation of and nuclear phosphorylation ofBcatenin in isolated mouse ABSCs at 1 UM
Cayman Chemical ArachIdonyl 2CLOroethylam 50mg
An analytical reference standard that is structurally similar to known phytocannabinoids intended for research and forensic applications