Guinea Pig Whole Blood
Cayman Chemical trnsVaccenIc ACD methyl S
An esterified form of trans-vaccenic acid; has been used as a standard for the identification and quantification of fatty acids in Uruguayan Colonia cheese by GC-MS
Cayman Chemical 7 12DIketolIthocholIc ACD
A bile acid; increased in the plasma of patients with cholestasis
Cayman Chemical LInoelaIdIc ACD methyl STR
An esterified form of linoelaidic acid; has been found in H. sabdariffa essential oil as well as biodiesel produced from sea mango seed oil
Cayman Chemical TaurochenodeoxycholIc ACD
A taurine-conjugated form of CDCA; serum levels increase approximately 5-fold in within two hours and begin to decrease within four hours during an oral lipid tolerance test in humans; serum levels are increased in patients with liver cirrhosis and may serve as a marker of disease progression
Cayman Chemical DocosahexaenoIc ACD Alkyn
An ω-alkyne derivative of docosahexaenoic acid; can be joined with azide-containing molecules using click chemistry; can be used track fatty acid metabolism in cells via click chemistry linkage to fluorophores
Cayman Chemical 3AmInopropylphosphonIc ACD
A partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding assay); induces relaxation in unstimulated isolated guinea pig ileum longitudinal muscle; completely inhibits GABA- and baclofen-induced inhibition of vagally stimulated bronchospasms in guinea pigs (5 mg/kg); reverses the antitussive effect of baclofen in cats (3 mg/kg)
Cayman Chemical JWH 203 NpentnoIc ACD meta
An internal standard for the quantification of JWH 203 N-pentanoic acid metabolite by GC- or LC-MS
Cayman Chemical DocosahexaenoIc ACD ethyl50UG
An internal standard for the quantification of docosahexaenoic acid ethyl ester by GC- or LC-MS
Cayman Chemical Linolenic ACD 1g
γ-Linolenic acid is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. γ-Linolenic acid produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.{2361}
Cayman Chemical GlycochenodeoxycholIc ACD
A glycine-conjugated form of chenodeoxycholic acid; reduces formation of cholic acid in primary human hepatocytes at 100 µM; reduces the number LC3 puncta and is cytotoxic to L-02 hepatocytes at 50, 75, and 100 µM; induces apoptosis in isolated rat hepatocytes at 50 µM; fecal levels are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet
Cayman Chemical GlycochenodeoxycholIc ACD
A glycine-conjugated form of chenodeoxycholic acid; reduces formation of cholic acid in primary human hepatocytes at 100 µM; reduces the number LC3 puncta and is cytotoxic to L-02 hepatocytes at 50, 75, and 100 µM; induces apoptosis in isolated rat hepatocytes at 50 µM; fecal levels are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet
Cayman Chemical 3AmInopropylphosphonIc ACD
A partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding assay); induces relaxation in unstimulated isolated guinea pig ileum longitudinal muscle; completely inhibits GABA- and baclofen-induced inhibition of vagally stimulated bronchospasms in guinea pigs (5 mg/kg); reverses the antitussive effect of baclofen in cats (3 mg/kg)