Goat Secondary Antibodies
Cayman Chemical CreatIn Phosphate 10g
A phosphorylated form of creatine; reduces hydrogen peroxide- and ferrous ion-induced increases in MDA levels in rat heart microsomes at 10 mM; prevents hydrogen peroxide-induced decreases in aortic flow, minute work, and peak aortic pressure in isolated perfused rat hearts at 10 mM; brain levels decrease following mild traumatic brain injury in rats
ABclonal Technology CLIC1 Rabbit pAb
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family, the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
![Biolegend Spark PLUS V450 anti-mouse CD4 [RM4-5] Isotype Rat IgG2a Reactivity Mouse Apps FC Size 25 ug](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Biolegend Spark PLUS V450 anti-mouse CD4 [RM4-5] Isotype Rat IgG2a Reactivity Mouse Apps FC Size 25 ug
Spark PLUS V450 anti-mouse CD4 [RM4-5] Isotype Rat IgG2a Reactivity Mouse Apps FC Size 25 ug
Cayman Chemical ChenodeoxycholIc AcIdodIum 5g
A primary bile acid; an FXR agonist that binds to FXRs in a TR-FRET assay (EC50 = 13 µM) and induces FXR transactivation in a reporter assay; induces transcription of GCL in primary hepatocytes and HepG2 cells from 25-100 µM
Cayman Chemical 3-ButylIdenphthalIde 25g
A plant metabolite with diverse biological activities; induces apoptosis and inhibits migration and EMT in 5637, BFTC-905, T24, and TCCSUP cells at 60 UG/ml; reduces tumor volume in a BFTC-905 mouse xenograft model at 100 and 200 mg/kg; increases life span and reduces spinal motor neuron loss in an SOD1G93A mouse model of ALS at 400 mg/kg; reduces polyQ accumulation and cerebral atrophy, as well as improves motor coordination in a mouse model of SCA3
Cayman Chemical 2-FluoroadenIn 250mg
A heterocyclic building block; has been used in the synthesis of Hsp90 inhibitors that have anticancer activity in vitro; cytotoxic to CEM human leukemia cells (IC50 = 0.15 µM)
Cayman Chemical CholInchlorIde 250g
An essential nutrient with roles in liver, neurological, hematological, and skeletal muscle homeostasis; a precursor in the biosynthesis of membrane phospholipids and to the neurotransmitter acetylcholine; is required for hepatic lipid transport; perinatal administration improves prenatal alcohol exposure-induced cognitive deficits in rats at 18.8 mg/kg; improves motor coordination and behavioral deficits in a mouse model of Rett syndrome at 13 mg/animal per day; improves deficits in recognition memory induced by EArly-life iron deficiency in rats at 5 ppm in the drinking water; deficiences are positively correlated with muscle wasting; dietary administration increases leg and breast muscle protein content in broiler chickens
Cayman Chemical AcesulfamepotasIum salt 100g
A non-caloric sweetener; has been found in wastewater and is considered a pollutant
Cayman Chemical DocosnoIc AcId 5g
A long-chain saturated fatty acid; binds to the DNA binding domain of p53 (Kd = 12 nM) and inhibits the DNA binding activity; inhibits rat DNA polymerase β and human DNA polymerase λ activity at 100 µM; inhibits human DNA topoisomerase I and II relaxation activity at 25 µM; liver levels are reduced in rats fed a high-fat or a high-fat high-cholesterol diet
ABclonal Technology RPL7A Rabbit pAb
Cytoplasmic ribosomes, responsible for protein synthesis, consist of a small 40S subunit and a large 60S subunit, made up of 4 RNA species and approximately 80 proteins. This gene encodes a ribosomal protein in the 60S subunit, belonging to the L7AE family. The protein can interact with nuclear hormone receptors, including the thyroid hormone receptor, inhibiting their DNA binding and transactivation. This gene is part of the surfeit gene cluster, which contains tightly linked genes with no sequence similarity. It is co-transcribed with small nucleolar RNA genes U24, U36a, U36b, and U36c in its introns. The gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein combining ribosomal protein L7a and the receptor tyrosine kinase domain of trk. As typical for ribosomal proteins, multiple processed pseudogenes exist for this gene in the genome.
Cayman Chemical 2 2BIpyrIdIn5 5dIcarbox 1g
A heterocyclic building block; has been used in the synthesis of metal-organic frameworks for water oxidation, organic photocatalysis, and carbon dioxide reduction
Cayman Chemical 1 2 3TrIundecnoyl GlycRol 50mg
A triacylglycerol; dietary administration prevents fasting-induced decreases in plasma glucose, alanine, and insulin levels, as well as the ratio of insulin to glucagon, in rats
Cayman Chemical THUNDRPhosphoAKT pnT30 9600Wel
Sandwich TR-FRET immunoassay for semi-quantitative detection of Phospho-AKT 1/2/3 (T308) in cell lysates
ABclonal Technology 488 anti-Human Galectin 3
This gene encodes a member of the galectin family of carbohydrate binding proteins Members of this protein family have an affinity for beta-galactosides The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands This protein localizes to the extracellular matrix the cytoplasm and the nucleus This protein plays a role in numerous cellular functions including apoptosis innate immunity cell adhesion and T-cell regulation The protein exhibits antimicrobial activity against bacteria and fungi Alternate splicing results in multiple transcript variants
ABclonal Technology Profilin1 Rabbit pAb
This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.