Rabbit Secondary Antibodies
ABclonal Technology PE Rabbit anti-Human CD74 mAb
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which when bound to the encoded protein initiates survival pathways and cell proliferation This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta) Multiple alternatively spliced transcript variants encoding different isoforms have been identified
American Research Products Inc Rabbit cross linked C telopept
Rabbit cross linked C-telopeptide of type II collagen (CTX-II) ELISA Kit from CUSABIO Detection Range 0 625 ng/mL-40 ng/mL Sensitivity 0 156 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Cell Signaling Technology COL1A1 E3I2I Rabbit mAb BSA and Azide Free 100 ug
COL1A1 E3I2I Rabbit mAb BSA and Azide Free 100 ug
ABclonal Technology EXOC3 Rabbit mAb
The protein encoded by this gene is a component of the exocyst complex a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane Though best characterized in yeast the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes At least eight components of the exocyst complex including this protein are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery The complex is also essential for the biogenesis of epithelial cell surface polarity
Cayman Chemical IgG2cmouse RabbIt MoncLN 100ug
Immunogen: Mouse IgG2c • Host: Rabbit • Species Reactivity: (+) Mouse • Cross Reactivity: (-) Human, rat IgG; (-) Mouse IgG1, IgG2a, IgG2b, IgG3, IgA, IgE, IgM • Applications: ELISA, WB (non-reducing conditions)
ABclonal Technology ITPR3 Rabbit mAb
This gene encodes a receptor for inositol 1 4 5-trisphosphate a second messenger that mediates the release of intracellular calcium The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus Knockout studies in mice suggest that type 2 and type 3 inositol 1 4 5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth
ABclonal Technology SIRT7 Rabbit mAb
This gene encodes a member of the sirtuin family of proteins homologs to the yeast Sir2 protein Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes The functions of human sirtuins have not yet been determined however yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity The protein encoded by this gene is included in class IV of the sirtuin family
ABclonal Technology ATP5G1 Rabbit mAb
This gene encodes a subunit of mitochondrial ATP synthase Mitochondrial ATP synthase catalyzes ATP synthesis utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation ATP synthase is composed of two linked multi-subunit complexes the soluble catalytic core F1 and the membrane-spanning component Fo comprising the proton channel The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha beta gamma delta and epsilon) assembled with a stoichiometry of 3 alpha 3 beta and a single representative of the other 3 The proton channel seems to have nine subunits (a b c d e f g F6 and 8) This gene is one of three genes that encode subunit c of the proton channel Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein Alternatively spliced transcript variants encoding the same protein have been identified
ABclonal Technology DLX3 Rabbit mAb
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll) a gene expressed in the head and limbs of the developing fruit fly The Distal-less (Dlx) family of genes comprises at least 6 different members DLX1-DLX6 Trichodentoosseous syndrome (TDO) an autosomal dominant condition has been correlated with DLX3 gene mutation This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17 Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism
ABclonal Technology PE Rabbit anti-Mouse CD40 mAb
Predicted to enable antigen binding activity protein domain specific binding activity and ubiquitin protein ligase binding activity Involved in B cell mediated immunity CD40 signaling pathway and cellular calcium ion homeostasis Acts upstream of or within several processes including defense response to other organism positive regulation of B cell activation and positive regulation of interleukin-12 production Located in external side of plasma membrane and intracellular membrane-bounded organelle Part of CD40 receptor complex Is expressed in several structures including alimentary system brain hemolymphoid system gland liver and biliary system and reproductive system Human ortholog(s) of this gene implicated in several diseases including Kawasaki disease autoimmune disease (multiple) end stage renal disease hyperimmunoglobulin syndrome (multiple) and non-Hodgkin lymphoma (multiple) Orthologous to human CD40 (CD40 molecule)
ABclonal Technology Nup107 Rabbit mAb
This gene encodes a member of the nucleoporin family The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC) All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized
ABclonal Technology UFM1 Rabbit mAb
UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1 MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M MIM 603173) (Komatsu et al 2004 [PubMed 15071506])
ABclonal Technology TOM70 Rabbit mAb
This gene encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex This protein is involved in the import of mitochondrial precursor proteins The protein interacts with the SARS-CoV and SARS-Cov-2 ORF9b proteins