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Bioassays, kits, and reagents used to analyze various properties of living cell samples. Products include apoptosis assays, signal transduction assays, and cell growth and differentiation assays.
LanthaScreen™ TR-FRET ER alpha Competitive Binding Kit provides a sensitive and robust method for high-throughput screening (HTS) of ligands for estrogen receptor (ER) alpha.
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The Glutamine/Glutamate-Glo Assay is a bioluminescent assay for rapid, selective and sensitive detection of glutamine and glutamate in biological samples. The assay is based on the conversion of glutamine to glutamate by Glutaminase enzyme.
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A bioluminescent assay for rapid and sensitive measurement of glucose from a variety of sample types. The assay is suitable for detecting altered glucose consumption due to changes in glycolysis or glucose production during gluconeogenesis.
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The GSH/GSSG-Glo™ Assay is a luminescence-based system for the detection and quantification of total glutathione (GSH +GSSG), GSSG and GSH/GSSG ratios in cultured cells.
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The Caspase-Glo 1 Inflammasome Assay is a homogeneous, bioluminescent method to selectively measure the activity of caspase-1, a member of the cysteine aspartic acid-specific protease (caspase) family and an essential component of the inflammasome.
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The Viral ToxGlo™ Assay is a simple, quantifiable method of determining viral-induced cytopathic effects (CPE) in host cells caused by lytic virions. The assay measures cellular ATP as a surrogate measure of host cell viability.
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pHAb Amine Reactive Dye exhibits very low fluorescence at pH > 7 and much higher fluorescence as the pH of the solution becomes acidic. pHAb Dyes are designed specifically for antibody labeling.
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Perform fast add-and-read assays directly on cells with the no-wash Immunoassay for HMGB1 Detection. Detects human or mouse HMGB1 using luminescent detection with just a plate-reading luminometer.
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The P450-Glo CYP3A4 Assay System provides a homogeneous, luminescent method for measuring CYP3A4 activity and the screening system contains a complete set of reagents for performing the assay.
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The T Cell Activation Bioassays are bioluminescent cell-based assays that overcome the limitations of existing assays and can be used for the discovery and development of novel biologics such as bispecific antibodies and CAR-T cell therapies.
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Homogeneous, colorimetric cell viability assay; requires mixing of MTS and PMS components prior to assay, then a 1- to 4-hour incubation. Standalone MTS powder for applications where optimization of assay for specific cell types or conditions is desired.
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