Apoptosis Reagents and Kits
Biotium Oxazole Yellow, 1 mM in DMSO
Oxazole yellow, also know as YO-PRO-1, is a green-fluorescent, cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain. The dye is nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima at 491/509 nm when bound to nucleic acids. Oxazole yellow is also used to identify apoptotic cells. Early apoptotic cells become permeant to oxazole yellow, but remain impermeant to propidiumiodide, a dead cell stain. Properties: Orange solution; Ex/Em= 491/509 nm (with DNA); Store at -20°C and protect from light; C24H29I2N3O, MW: 629.32; [152068-09-2].
Abcam Human OAS1 knockout A549 cell lysate.
Human OAS1 knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human KRT13 knockout A-431 cell lysate.
Human KRT13 knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human GHR (Growth Hormone Receptor) Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human GHR (Growth Hormone Receptor) Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human GHR (Growth Hormone Receptor).
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Annexin V-Biotin/PI Apoptosis Kit 200 assays
Annexin V is a Ca2 dependent phospholipid-binding protein that specifically binds to phosphatidylserine (PS) Normally PS resides on the inner surface of the cell membrane s phospholipid bilayer During early stages of apoptosis it translocates from the inner leaflet to the outer surface thus exposing itself to the extracellular environment Biotin labeled Annexin V can be detected through binding with fluorescently labeled streptavidin (such as fluorescein-conjugated streptavidin or PE-conjugated streptavidin) The occurrence of apoptosis can then be identified using flow cytometry or fluorescence microscopy within only 10 to 20 minutes PI (propidium iodide) binds specifically to double-stranded DNA producing a red fluorescence signal PI cannot penetrate the intact cell membrane but late apoptotic and dead cells staining their nuclei Simultaneous staining with Annexin V-Biotin and PI permits differentiation among cells at various stages of apoptosis and dead cells
Abcam ISCK03, SCF/c-Kit inhibitor, 5MG
MW 355.5 Da, Purity >99%. Cell-permeable, selective SCF/c-Kit inhibitor (IC₅₀ < 2.5 μM). Blocks SCF-induced c-kit and Erk phosphorylation without affecting HGF-induced Erk phosphorylation. Shows antiangiogenic effects. Abolishes melanin production in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Sartorius CELL PLAYER96WELL KINETIC CASP
ONE VIAL (20 UL) OF 5 MM MIX AND READ REAGENT IN DMSO SUFFICIENT FOR 100-200 LIVE-CELL APOPTOSIS TESTS IN 96-WELL FORMAT
Abcam Human Plcb1 (Phospholipase C beta 1) knockout HeLa cell lysate.
Human Plcb1 (Phospholipase C beta 1) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Fc hGrancalcin h rec
Recombinant protein. Human Grancalcin aa 1-217 is fused at the N-terminus to the Fc portion of human IgG1. Source HEK 293 cells. Lyophilized. Contains PBS. Grancalcin is a member of a new family of proteins named penta-EF-hand PEF, which contains five repetitive EF hand motifs. PEF proteins form a unique group including calpain, sorcin, grancalcin, ALG-2 apoptosis-linked gene-2 protein and peflin. The penta-EF hand members are Ca2-binding proteins implicated in regulating cell migration, apoptosis and the mobilization of immune cells. Senescent cells accumulate in the bone marrow and secrete factors, termed senescence-associated secretory phenotype SASP, that can promote skeletal aging. Recently, senescent neutrophils and macrophages in the bone marrow were shown to be critical cell types during skeletal aging releasing Grancalcin GCA to promote such aging.
ABclonal Technology Caspase-1 Rabbit pAb
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
Abcam Human HSP90AA1 (Hsp90 alpha) knockout HEK-293T cell lysate.
Human HSP90AA1 (Hsp90 alpha) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human HNRNPA1 knockout HEK-293T cell lysate.
Human HNRNPA1 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human STK4 (Serine/threonine-protein kinase 4/MST-1) knockout HeLa cell lysate.
Human STK4 (Serine/threonine-protein kinase 4/MST-1) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human FOXO3 (FOXO3A) knockout HEK-293 cell lysate.
Human FOXO3 (FOXO3A) knockout HEK-293 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement