Signal Transduction Reagents and Kits
Promega ADP-Glo™ Kinase Assay + ALK6 Kinase Enzyme System
ALK6 (also known as BMPR1B) is a member of the transmembrane serine/threonine kinase that is the member of the bone morphogenetic protein (BMP) receptor, which is closely related to the activin receptors, ACVR1 and ACVR2.
Promega ADP-Glo™ Kinase Assay + PIM2 Kinase Enzyme System
Recombinant full-length human PIM2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PIM2 is a serine threonine kinase that is present in all tissues.
Promega SRC Kinase Enzyme System, 1mg
Recombinant full-length human SRC was expressed in E. coli cells using an N-terminal GST tag. SRC was originally identified as a transforming protein of the Rous sarcoma virus that had enzymatic ability to phosphorylate tyrosine in protein substrates.
Promega EPHA1 Kinase Enzyme System, 1mg
Recombinant mouse EPHA1 (amino acids 569-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EPHA1 is a member of the Eph family of receptor tyrosine kinases that have been implicated in mediating developmental events.
Promega ADP-Glo™ Kinase Assay + RSK1 Kinase Enzyme System
Recombinant full-length human RSK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. RSK1 is a member of the RSK (ribosomal S6 kinase) family that consists of growth factor-regulated serine/threonine kinases.
Promega ABL1 Kinase Enzyme System, 1mg
Recombinant human ABL1 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase implicated in processes of cell differentiation, cell division and others.
Promega NUAK2 Kinase Enzyme System, 1mg
Recombinant full-length human NUAK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. NUAK2 or SNF1/AMP kinase-related kinase (SNARK) is a member of the NUAK family of SNF1-like kinase 2.
Promega ADP-Glo™ Kinase Assay + RIPK2 Kinase Enzyme System
RIPK2 (RIP2; RICK) is a death domain-containing protein kinase encoding a predicted 540-amino acid protein that contains an N-terminal serine/threonine kinase catalytic domain and a C-terminal caspase activation and recruitment domain.
Promega ADP-Glo™ Kinase Assay + ALK2 Kinase Enzyme System
ALK2 is a receptor serine/threonine kinase that is member of the ALK family and is upstream of signaling pathway involving the SMAD proteins especially SMAD1/5/8.
Promega ADP-Glo™ Kinase Assay + CDK6/CyclinD3 Kinase Enzyme System
Recombinant full-length human CDK6 and CyclinD3 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal His tag on both proteins.
Promega BMX Kinase Enzyme System, 10microg
Recombinant full-length human BMX was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells.
Promega CLK1 Kinase Enzyme System, 10microg
Recombinant human CLK1 (129-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CLK1, also known as STY, is a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases.
Promega PASK Kinase Enzyme System, 1mg
Recombinant human PASK (981-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PASK or PAS domain containing serine/threonine kinase regulates the function of many intracellular signaling pathways involved in stress.
Promega ADP-Glo™ Kinase Assay + PKCε Kinase Enzyme System
Recombinant full-length human PKC epsilon was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PKC epsilon is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases.
Promega ADP-Glo™ Kinase Assay + SLK Kinase Enzyme System
Recombinant full-length human SLK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. SLK or LOSK is a Ste20-like protein kinase that associates with microtubule and centrosome.